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BIOSS INC
Artikel-Nr:
(BOSSBS-8396R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8396R-A647
Lokale Artikelnummer::
BOSSBS-8396R-A647
Beschreibung:
FBXO15, also known as FBX15, is a 434 amino acid protein that contains one C-terminal F-box domain and belongs to the F-box family of proteins. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO15 can directly interact with Skp1 p19 and CUL-1. In addition, FBXO15 is a target of the transcription factor Oct-3/4, however, it does not appear to be essential for early development and fertility.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6059R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6059R-A555
Lokale Artikelnummer::
BOSSBS-6059R-A555
Beschreibung:
Immediate-early protein likely to play a role in cell growth regulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6110R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6110R-CY3
Lokale Artikelnummer::
BOSSBS-6110R-CY3
Beschreibung:
SPARC (secreted protein acidic and rich in cysteine) is a phosphorylated, acidic, glycine-rich glycoprotein that is secreted by endothelial cells and is present in large amounts in the parietal endoderm of mouse embryos and in human placenta. SPARC-like protein 1 (SPARCL1), also known as high endothelial venule protein (Hevin) or MAST9, is a 664 amino acid member of the SPARC family of proteins. Highly expressed in lymph node, heart, lung, brain, skeletal muscle, ovary, colon and small intestine, SPARCL1 is a secreted protein that contains one EF-hand domain, one follistatin-like domain and one Kazal-like domain. SPARCL1 is implicated to play a role in neuronal remodeling and tumor suppression. The gene encoding SPARCL1 maps to chromosome 4q22.1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1697R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1697R-CY5.5
Lokale Artikelnummer::
BOSSBS-1697R-CY5.5
Beschreibung:
Defensins are a group of cyclic peptides containing 29-35 amino acids, which comprise approximately 30% of the total protein content of neutrophil azurophilic granules. Various functions have been reported for the defensins, including antibacterial and antifungal activity and chemotactic activity for monocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6448R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6448R-CY3
Lokale Artikelnummer::
BOSSBS-6448R-CY3
Beschreibung:
EGR3 is a member of the early growth response transcription factor family of C2H2 zinc finger proteins (other members EGR1, EGR2 and EGR4). EGR proteins are immediate early proteins, expression of which is swiftly upregulated in response to a wide range of extracellular stimuli. EGR3 is also thought to be involved in development of muscle spindles, and is upregulated in several regions of the brain in response to stress or injury.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12393R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12393R-A647
Lokale Artikelnummer::
BOSSBS-12393R-A647
Beschreibung:
Bcl-9L is a 1,499 amino acid protein that localizes to the nucleus and contains a specialized C-terminal domain that is important for its overall activity. Expressed in breast tissue, as well as in eye, lung, prostate and various carcinomas, Bcl-9L functions as a transcriptional activator that forms a complex with Parafibromin and β-catenin and is thought promote the transcriptional activity of Parafibromin and enhance the neoplastic transforming activity of β-catenin. Bcl-9L exists as multiple alternatively spliced isoforms and is thought to be involved in tumorigenesis, possibly playing a role in tumor transformation and metastasis. The gene encoding Bcl-9L maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11405R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11405R-A350
Lokale Artikelnummer::
BOSSBS-11405R-A350
Beschreibung:
Relaxin Receptor 3 is a G protein-coupled receptor that binds Relaxin 3 and influences differentiation and maintenance of the nervous system. Relaxin Receptor 3 shares sequence similarity with somatostatin receptors and angiotensin receptors. It mediates central processing of sensory signals in the rat and is thought to be a modulator of stress responses. Relaxin Receptor 3 is present in the brain, with highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, and low level expression in cerebellum. In peripheral tissues there are high levels in adrenal glands and low levels in pancreas, salivery gland, placenta, mammary gland and testis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3176R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3176R
Lokale Artikelnummer::
BOSSBS-3176R
Beschreibung:
Anti-HIST1H1E Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15414R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15414R-A647
Lokale Artikelnummer::
BOSSBS-15414R-A647
Beschreibung:
HAUS3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2549R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2549R
Lokale Artikelnummer::
BOSSBS-2549R
Beschreibung:
Anti-CXCL5 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9477R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9477R-A750
Lokale Artikelnummer::
BOSSBS-9477R-A750
Beschreibung:
May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes. Myomegalin, is a 2346 amino acid protein that contains one NBPF domain and localizes to the nucleus, cytoplasm, centrosome and Golgi apparatus. Expressed at high levels in fetal and adult heart and at lower levels in brain and placenta, myomegalin is thought to function as an anchoring protein that sequesters members of the cAMP-dependent pathway to the Golgi and to centrosomes, thereby mediating cAMP pathway dynamics. Translocations in the gene that encodes myomegalin are associated with myeloproliferative disorders (MBDs), a group of diseases caused by an overproduction of blood cells. Myomegalin exists as twelve isoforms due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9253R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9253R
Lokale Artikelnummer::
BOSSBS-9253R
Beschreibung:
RNF133 contains a RING finger domain, a motif known to be involved in protein-protein and protein-DNA interactions. This gene has no intron. RNF133 may have E3 ubiquitin-protein ligase activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8580R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8580R-CY5
Lokale Artikelnummer::
BOSSBS-8580R-CY5
Beschreibung:
GRAMD3 is a 432 amino acid protein that contains one GRAM domain and is encoded by a gene that maps to human chromosome 5q23.2. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1603R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1603R
Lokale Artikelnummer::
BOSSBS-1603R
Beschreibung:
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11473R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11473R
Lokale Artikelnummer::
BOSSBS-11473R
Beschreibung:
Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway. It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0498R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0498R-CY5.5
Lokale Artikelnummer::
BOSSBS-0498R-CY5.5
Beschreibung:
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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