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BIOSS INC
Artikel-Nr:
(BOSSBS-3907R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3907R-A647
Lokale Artikelnummer::
BOSSBS-3907R-A647
Beschreibung:
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15491R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15491R
Lokale Artikelnummer::
BOSSBS-15491R
Beschreibung:
Anti-HIGD2A Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1158R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1158R-FITC
Lokale Artikelnummer::
BOSSBS-1158R-FITC
Beschreibung:
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 8% of all plasma zinc.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4969R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4969R-CY3
Lokale Artikelnummer::
BOSSBS-4969R-CY3
Beschreibung:
ANXA2R (annexin-2 receptor), also known as AX2R or C5orf39, is a 193 amino acid protein that is widely expressed and may act as an annexin II receptor on marrow stromal cells to induce osteoclast formation. In addition, ANXA2R is highly expressed in lymphocytes and is also found in resting CD4+ and CD8+ T cells. The gene encoding ANXA2R maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6779R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6779R-A488
Lokale Artikelnummer::
BOSSBS-6779R-A488
Beschreibung:
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5395R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5395R-FITC
Lokale Artikelnummer::
BOSSBS-5395R-FITC
Beschreibung:
Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13240R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13240R-A555
Lokale Artikelnummer::
BOSSBS-13240R-A555
Beschreibung:
Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, preventing entry into mitosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3936R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3936R-FITC
Lokale Artikelnummer::
BOSSBS-3936R-FITC
Beschreibung:
Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1289R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1289R-HRP
Lokale Artikelnummer::
BOSSBS-1289R-HRP
Beschreibung:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4033R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4033R-A555
Lokale Artikelnummer::
BOSSBS-4033R-A555
Beschreibung:
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9480R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9480R-CY7
Lokale Artikelnummer::
BOSSBS-9480R-CY7
Beschreibung:
May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2794R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2794R-A488
Lokale Artikelnummer::
BOSSBS-2794R-A488
Beschreibung:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8174R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8174R-FITC
Lokale Artikelnummer::
BOSSBS-8174R-FITC
Beschreibung:
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis.Tissue specificity:Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11323R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11323R-A647
Lokale Artikelnummer::
BOSSBS-11323R-A647
Beschreibung:
Neuroglycan C is a brain-specific chondroitin sulfate proteoglycan (CSPG) implicated in the proliferation of neural stem and progenitor cells. Neuro-glycan C is a single-pass membrane protein that can manifest as a part-time proteoglycan depending on the tissue expressing it. In its proteoglycan form, Neuroglycan C exhibits chondroitin sulfate glycans and functions as a receptor for midkine, a growth factor that binds heparin, to affect cytoskeletal changes. By means of ectodomain shedding, the ectodomain of Neuroglycan C is able to enhance neurite outgrowth from neurons. Neurite growth stimulation is affected by both an EGF-like and an acidic amino acid domain found on the shed ectodomain. Both domains instigate neurite growth, however, these domains exhibit differing functionality as to number of neurites produced and neuron types stimulated.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11600R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11600R-A680
Lokale Artikelnummer::
BOSSBS-11600R-A680
Beschreibung:
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0547R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0547R-A350
Lokale Artikelnummer::
BOSSBS-0547R-A350
Beschreibung:
COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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