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BIOSS INC
Artikel-Nr:
(BOSSBS-5421R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5421R-A555
Lokale Artikelnummer::
BOSSBS-5421R-A555
Beschreibung:
Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5552R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5552R-CY7
Lokale Artikelnummer::
BOSSBS-5552R-CY7
Beschreibung:
Parkinson's Disease, the second most common neurodegenerative disease after Alzheimer's Disease, is characterized by the loss of dopaminergic neurons and the presence of Lewy bodies (comprised of alpha synuclein and parkin inclusions). Autosomal Recessive Juvenile Parkinsonism (AR-JP) is a recently described form of Parkinson's Disease that has been linked to a gene that codes for parkin. Parkin, a 52 kDa protein, has a suggested role in the ubiquitin/proteasome pathway for protein degradation. The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, thus targeting them for degradation by the proteasome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5467R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5467R-CY7
Lokale Artikelnummer::
BOSSBS-5467R-CY7
Beschreibung:
Gamma Catenin is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of gamma Catenin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. It is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5394R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5394R-A555
Lokale Artikelnummer::
BOSSBS-5394R-A555
Beschreibung:
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4550R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4550R-A555
Lokale Artikelnummer::
BOSSBS-4550R-A555
Beschreibung:
Pectinesterase
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5067R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5067R-CY7
Lokale Artikelnummer::
BOSSBS-5067R-CY7
Beschreibung:
Hydroxymethylglutaryl-CoA lyase (HMGCL) is found in fibroblasts, liver and lymphoblasts. It has a role in ketogenesis and leucine catabolism. Defects in HMGCL are the cause of 3-hydroxy-3-methylglutaryl-CoA lyase deficiency (hydroxymethylglutaricaciduria), an autosomal recessive disease which can lead to hypoglycemia and coma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1007R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1007R-A680
Lokale Artikelnummer::
BOSSBS-1007R-A680
Beschreibung:
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1484R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1484R-CY3
Lokale Artikelnummer::
BOSSBS-1484R-CY3
Beschreibung:
catalyses the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0299R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0299R-A750
Lokale Artikelnummer::
BOSSBS-0299R-A750
Beschreibung:
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1205R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1205R-A680
Lokale Artikelnummer::
BOSSBS-1205R-A680
Beschreibung:
Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fibre and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP3, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p9RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca(2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1484R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1484R-A750
Lokale Artikelnummer::
BOSSBS-1484R-A750
Beschreibung:
catalyses the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1025R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1025R-A750
Lokale Artikelnummer::
BOSSBS-1025R-A750
Beschreibung:
Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3637R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3637R-A680
Lokale Artikelnummer::
BOSSBS-3637R-A680
Beschreibung:
TSPAN5 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterised by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15287R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15287R-CY3
Lokale Artikelnummer::
BOSSBS-15287R-CY3
Beschreibung:
C8ORF34.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8273R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8273R-A680
Lokale Artikelnummer::
BOSSBS-8273R-A680
Beschreibung:
The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP7 (GTPase IMAP family member 7), also known as IAN7 (immunity-associated nucleotide 7), is a 300 amino acid protein encoded by a gene that maps to human chromosome 7q36.1. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterised by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2352R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2352R-A750
Lokale Artikelnummer::
BOSSBS-2352R-A750
Beschreibung:
Cytochromes P45 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidises a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,4-cineole 2-exo-monooxygenase.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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