Supplier >
BIOSS INC
Drucken
Sie suchten nach:
92 239 results were found
BIOSS INC
Artikel-Nr:
(BOSSBS-2159R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2159R-CY7
Lokale Artikelnummer::
BOSSBS-2159R-CY7
Beschreibung:
Glypicans are glycosylphosphatidylinositol-anchored heparan sulphate proteoglycans, which are thought to modulate signalling by growth factors, including fibroblast growth factors and Wnts. Expression of glypican-4 has been reported in the mouse brain at embryonic day 7 and later stages.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11604R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11604R-A488
Lokale Artikelnummer::
BOSSBS-11604R-A488
Beschreibung:
Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8113R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8113R-CY7
Lokale Artikelnummer::
BOSSBS-8113R-CY7
Beschreibung:
CCDC127
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5901R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5901R-A680
Lokale Artikelnummer::
BOSSBS-5901R-A680
Beschreibung:
Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3412R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3412R-FITC
Lokale Artikelnummer::
BOSSBS-3412R-FITC
Beschreibung:
The SHC gene encodes for a signaling and transforming protein containing Src homology 2 and 3 (SH2 and SH3) domains. The SHC gene encodes 2 widely expressed overlapping proteins of 46 and 52 kD, both containing a C-terminal SH2 domain. Adjacent to the SH2 region is a glycine and proline rich region. These 2 proteins differ in their N terminals. SHC proteins are involved in mitogenic signal transduction and act by coupling growth factor receptors to the RAS signaling pathway. The protein encoded by the SHC1 gene is thought to act as an adaptor in many signal transduction pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4538R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4538R-CY3
Lokale Artikelnummer::
BOSSBS-4538R-CY3
Beschreibung:
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6384R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6384R
Lokale Artikelnummer::
BOSSBS-6384R
Beschreibung:
C10orf28 is a 792 amino acid protein that exists as three alternatively spliced isoforms. The gene encoding C10orf28 maps to human chromosome 10, which spans nearly 135 million base pairs, makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8261R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8261R-HRP
Lokale Artikelnummer::
BOSSBS-8261R-HRP
Beschreibung:
DHRS13 (dehydrogenase/reductase SDR family member 13), also known as UNQ419/PRO853, is a 377 amino acid secreted protein belonging to the short-chain dehydrogenases/reductases (SDR) family. DHRS13 is presumed to function as an oxidoreductase and is phosphorylated, potentially by ATM or ATR, upon DNA damage. DHRS13 exists as two isoforms produced by alternative splicing events. The gene encoding DHRS13 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Neurofibromatosis, dysregulated Schwann cell growth, Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are associated with chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8070R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8070R-CY5
Lokale Artikelnummer::
BOSSBS-8070R-CY5
Beschreibung:
ADCK4, AarF domain containing kinase 5, is a member of group i collagen (fibrillar forming collagen). The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr). There are 2 named isoforms produced by alternative splicing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3186R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3186R-A555
Lokale Artikelnummer::
BOSSBS-3186R-A555
Beschreibung:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8615R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8615R-A350
Lokale Artikelnummer::
BOSSBS-8615R-A350
Beschreibung:
Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0050R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0050R-CY5.5
Lokale Artikelnummer::
BOSSBS-0050R-CY5.5
Beschreibung:
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0174R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0174R-A647
Lokale Artikelnummer::
BOSSBS-0174R-A647
Beschreibung:
The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0861R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0861R-CY3
Lokale Artikelnummer::
BOSSBS-0861R-CY3
Beschreibung:
2,4-Dichlorophenoxyacetic acid (2,4-D) is a common systemic herbicide used in the control of broadleaf weeds. It is the most widely used herbicide in the world, and the third most commonly used in North America. [1] 2,4-D is also an important synthetic auxin, often used in laboratories for plant research and as a supplement in plant cell culture media such as MS medium. 2,4-D is a synthetic auxin, which is a class of plant growth regulators. It is absorbed through the leaves and is translocated to the meristems of the plant. Uncontrolled, unsustainable growth ensues causing stem curl-over, leaf withering, and eventual plant death. 2,4-D is typically applied as an amine salt, but more potent ester versions exist as well.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13730R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13730R-CY3
Lokale Artikelnummer::
BOSSBS-13730R-CY3
Beschreibung:
Required for zonula adherens biogenesis and maintenance. Acts via its interaction with KIAA1543/Nezha, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9543R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9543R-CY7
Lokale Artikelnummer::
BOSSBS-9543R-CY7
Beschreibung:
Chromosome 7 is about 158 milllion bases long, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The C7orf28 gene product has been provisionally designated C7orf28 pending further characterization.
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
