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2\'-Chlor-5\'-methylbiphenyl-3-carbonsäure
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2\'-Chlor-5\'-methylbiphenyl-3-carbonsäure
Artikel-Nr:
(BOSSBS-2702R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2702R-HRP
Lokale Artikelnummer::
BOSSBS-2702R-HRP
Beschreibung:
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5374R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5374R-A555
Lokale Artikelnummer::
BOSSBS-5374R-A555
Beschreibung:
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis; the function may involve SDCCAG3 and PTPN13 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0185R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0185R-A488
Lokale Artikelnummer::
BOSSBS-0185R-A488
Beschreibung:
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6094R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6094R-HRP
Lokale Artikelnummer::
BOSSBS-6094R-HRP
Beschreibung:
RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2702R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2702R-A350
Lokale Artikelnummer::
BOSSBS-2702R-A350
Beschreibung:
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3148R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3148R-A750
Lokale Artikelnummer::
BOSSBS-3148R-A750
Beschreibung:
Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. GSK3 has been implicated in fundamental cell processes such as cell fate determination, metabolism, transcriptional control and oncogenesis. Two isoforms, alpha (GSK3A; OMIM 606784) and beta, show a high degree of amino acid homology within their catalytic domains. GSK3B is involved in energy metabolism, neuronal cell development and body pattern formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0023M-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0023M-A488
Lokale Artikelnummer::
BOSSBS-0023M-A488
Beschreibung:
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2066R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2066R-FITC
Lokale Artikelnummer::
BOSSBS-2066R-FITC
Beschreibung:
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0023M-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0023M-FITC
Lokale Artikelnummer::
BOSSBS-0023M-FITC
Beschreibung:
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13108R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13108R-A750
Lokale Artikelnummer::
BOSSBS-13108R-A750
Beschreibung:
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8878R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8878R-CY5
Lokale Artikelnummer::
BOSSBS-8878R-CY5
Beschreibung:
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6094R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6094R
Lokale Artikelnummer::
BOSSBS-6094R
Beschreibung:
RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0028R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0028R-CY3
Lokale Artikelnummer::
BOSSBS-0028R-CY3
Beschreibung:
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2809R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2809R-FITC
Lokale Artikelnummer::
BOSSBS-2809R-FITC
Beschreibung:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2891R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2891R-CY5.5
Lokale Artikelnummer::
BOSSBS-2891R-CY5.5
Beschreibung:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4874R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4874R
Lokale Artikelnummer::
BOSSBS-4874R
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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