PROSCI
Artikel-Nr:
(PRSI36-306)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-306
Lokale Artikelnummer::
PRSI36-306
Beschreibung:
GPX1 is an antioxidant enzyme that is down-regulated in cancer cells. Protects the hemoglobin in erythrocytes from oxidative breakdown. Its main role is the prevention of cancer initiation by ROS-mediated DNA damage.
VE:
1 * 100 µG
Artikel-Nr:
(PRSIXP-5290)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5290
Lokale Artikelnummer::
PRSIXP-5290
Beschreibung:
TWEAK is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-157)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-157
Lokale Artikelnummer::
PRSI27-157
Beschreibung:
USP22 is a subunit of the SAGA transcriptional cofactor complex. It deubiquitylates histone H2B and is recruited to specific genes by activators like Myc. USP22 is needed for cell cycle progression. It deubiquitylates histone H2A in addition to H2B. Altered mRNA expression is associated with therapy failure and death in patients multiple types of cancer.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-057)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-057
Lokale Artikelnummer::
PRSI27-057
Beschreibung:
IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x (L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x (L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-747)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-747
Lokale Artikelnummer::
PRSI91-747
Beschreibung:
Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Coupleing activate of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI35-328)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
35-328
Lokale Artikelnummer::
PRSI35-328
Beschreibung:
Anti-Neisseria meningitidis Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 1 mL
Artikel-Nr:
(PRSI62-334)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-334
Lokale Artikelnummer::
PRSI62-334
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI77-109)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-109
Lokale Artikelnummer::
PRSI77-109
Beschreibung:
The 1A8 monoclonal antibody specifically reacts with the 21 to 25 kDa glycophosphatidylinositol-anchored protein known as Ly-6G, expressed by the granulocytes from the bone marrow and periphery neutrophils. Ly-6G and Ly-6C form the Granulocyte Receptor-1 antigen (GR-1). The binding of the 1A8 antibody to the Ly-6G can be blocked by another antibody, RB6-8C5, which also recognizes Ly-6C. While 1A8 is specific for only Ly-6G, RB6-8C5 also binds to Ly-6C.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI7189P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7189P
Lokale Artikelnummer::
PRSI7189P
Beschreibung:
18 amino acids near the center of human VTCN1.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-675)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-675
Lokale Artikelnummer::
PRSI91-675
Beschreibung:
Progonadoliberin-2, also known as Progonadoliberin II and GNRH2, belongs to the gonadotropin-releasing hormone family. GNRH2 is specially expressed in midbrain, at significantly higher levels outside the brain (up to 30-fold). GNRH2 can be cleaved into two chains, gonadoliberin-2 and GnRH-associated peptide 2. gonadoliberin-2 regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. The proproteins produce three transcript variants, but produce the same peptide hormone.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5625P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5625P
Lokale Artikelnummer::
PRSI5625P
Beschreibung:
BCAS1 pepide is used for blocking the activity of BCAS1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3173P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3173P
Lokale Artikelnummer::
PRSI3173P
Beschreibung:
TRIF peptide is used for blocking the activity of the TRIF antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI63-279)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-279
Lokale Artikelnummer::
PRSI63-279
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI6919P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6919P
Lokale Artikelnummer::
PRSI6919P
Beschreibung:
DELE peptide is used for blocking the activity of DELE antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI42-139)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-139
Lokale Artikelnummer::
PRSI42-139
Beschreibung:
Anti-ASAM Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI49-569)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
49-569
Lokale Artikelnummer::
PRSI49-569
Beschreibung:
Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure. For these reasons it is often extremely difficult to generate antibodies with specificities to collagens. The development of type specific antibodies is dependent on NON-DENATURED three-dimensional epitopes. Collagens are extensively purified for immunization from human and bovine placenta and cartilage by limited pepsin digestion and selective salt precipitation. This preparation results in a native conformation of the protein. Antibodies are isolated from rabbit antiserum and are extensively cross-adsorbed by immunoaffinity purification to produce 'type' specific antibodies. Greatly diminished reactivity and selectivity of these antibodies will result if denaturing and reducing conditions of SDS-PAGE and immunoblotting are used.
VE:
1 * 50 µG
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