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COMBI-BLOCKS
Artikel-Nr:
(PRSI24-242)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-242
Lokale Artikelnummer::
PRSI24-242
Beschreibung:
Anti-FAS Recombinant Antibody [Clone: Basiliximab]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI23-242)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-242
Lokale Artikelnummer::
PRSI23-242
Beschreibung:
Anti-ADH7 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI34-119)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
34-119
Lokale Artikelnummer::
PRSI34-119
Beschreibung:
This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI96-326)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-326
Lokale Artikelnummer::
PRSI96-326
Beschreibung:
Folate receptor beta is also known as Folate receptor 2, FBP, FOLR2, BETA-HFR, FBP/PL-1, FR-BETA, FR-P3, and is a member of the folate receptor (FOLR) family. and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. The FOLR2 protein was originally thought to exist only in placenta, but is also detected in spleen, bone marrow, and thymus. FOLR2 is predominantly expressed in placenta, cells of the neutrophilic lineage, and some CD34+ hematopoietic progenitor cells. It is upregulated on myeloid leukemias, head and neck squamous cell carcinomas, and several nonepithelial cancers. It is also upregulated on macrophages and monocytes at chronic inflammatory sites including rheumatoid arthritis synovium and glioblastoma. FOLR2 is a marker for macrophages generated in the presence of M-CSF, but not GM-CSF. Its expression correlates with increased folate uptake ability. Folate conjugates of therapeutic drugs are a potential immunotherapy tool to target tumor-associated macrophages.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI23-451)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-451
Lokale Artikelnummer::
PRSI23-451
Beschreibung:
Anti-SLC9A6 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI63-249)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-249
Lokale Artikelnummer::
PRSI63-249
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI42-034)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-034
Lokale Artikelnummer::
PRSI42-034
Beschreibung:
Anti-TUSC2 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI46-907)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-907
Lokale Artikelnummer::
PRSI46-907
Beschreibung:
Anti-TGFBR3 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-396)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-396
Lokale Artikelnummer::
PRSI27-396
Beschreibung:
FOXF1 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the regulation of pulmonary genes as well as embryonic development.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-129)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-129
Lokale Artikelnummer::
PRSI29-129
Beschreibung:
The function of the Anti-BTBD14B gene has not yet been determined
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-570)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-570
Lokale Artikelnummer::
PRSI28-570
Beschreibung:
C2ta is essential for transcriptional activity of the HLA class II promoter; activation is via the proximal promoter. No DNA binding of in vitro translated CIITA was detected. C2ta may act in a coactivator-like fashion through protein-protein interactions by contacting factors binding to the proximal MHC class II promoter, to elements of the transcription machinery, or both. Alternatively it may activate HLA class II transcription by modifying proteins that bind to the MHC class II promoter
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-887)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-887
Lokale Artikelnummer::
PRSI27-887
Beschreibung:
The protein encoded by BTG2 is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein is involved in the regulation of the G1/S transition of the cell cycle.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-476)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-476
Lokale Artikelnummer::
PRSI27-476
Beschreibung:
SMAD5 undergoes copy number gain and increased expression, rather than loss of expression, and therefore does not act as a tumor-suppressor gene in hepatocellular carcinoma. Up-regulated Smad5 mediates apoptosis of gastric epithelial cells induced by Helicobacter pylori infection.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-807)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-807
Lokale Artikelnummer::
PRSI27-807
Beschreibung:
Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5553)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5553
Lokale Artikelnummer::
PRSI5553
Beschreibung:
PICALM Antibody: PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery. Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia. PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2. Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI4811)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4811
Lokale Artikelnummer::
PRSI4811
Beschreibung:
OTUD5 Antibody: OTUD5 is a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and OTUD5 has been shown to suppress the type I interferon (IFN-I)-dependent innate immune response by cleaving the polyubiquitin chain from TRAF3, an essential type I interferon adaptor protein. Cleavage results in disassociation of TRAF3 from a downstream signaling complex containing TBK1 and the disruption of the IFN-I signaling cascade, indicating that OTUD5 acts as a negative regulator of innate immune responses. It has been suggested that by suppressing IFN-I production, OTUD5 may function to inhibit the emergence of certain autoimmune disorders such as systemic lupus erythematosus. Multiple isoforms of OTUD5 are known to exist.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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