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PROSCI


28 361  results were found

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Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 61-992
Lokale Artikelnummer:: PRSI61-992
Beschreibung:   For WB starting dilution is: 1:1000.
VE:  1 * 400 µl
New Product

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 25-784
Lokale Artikelnummer:: PRSI25-784
Beschreibung:   DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.
VE:  1 * 50 µG
Artikel-Nr: (PRSI27-291)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 27-291
Lokale Artikelnummer:: PRSI27-291
Beschreibung:   ELL was shown to encode a previously uncharacterized elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by polymerase at multiple sites along the DNA. Functionally, ELL resembles Elongin (SIII), a transcription elongation factor regulated by the product of the von Hippel-Lindau (VHL) tumor suppressor gene.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 62-581
Lokale Artikelnummer:: PRSI62-581
Beschreibung:   For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:  1 * 400 µl
New Product

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 92-675
Lokale Artikelnummer:: PRSI92-675
Beschreibung:   Human TNFSF14 Protein, also known as LIGHT, belongs to a member of the tumour necrosis factor (TNF) ligand family. It can bind to NFRSF3/LTBR. It is a ligand for TNFRSF14, which is a member of the tumour necrosis factor receptor superfamily, and it is also known as a herpesvirus entry mediator ligand (HVEML). TNFSF14 encodes a protein with a 37 aa cytoplasmic domain, 21aa transmembrane domain and 182 aa extracellular region. The gene is predominantly expressed in the spleen and also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumour lines. TNFSF14 protein was found to probably function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. Studies have shown that this protein can prevent tumour necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 26-664
Lokale Artikelnummer:: PRSI26-664
Beschreibung:   The exact function of C6orf150 remains unknown.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 26-102
Lokale Artikelnummer:: PRSI26-102
Beschreibung:   The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 6669
Lokale Artikelnummer:: PRSI6669
Beschreibung:   SLAIN1 Antibody: SLAIN1 is a novel stem cell protein that was identified by transciptional profiling of mouse and human embryonic stem cells (ESCs) and is expressed at the stem cell and epiblast stages. Unlike its more widely expressed homolog SLAIN2, SLAIN1 was found to be expressed in the epiblast, nervous system, tailbud and somites of the developing mouse embryo later experiments suggested that SLAIN1 may play a role in the development of the nervous system as well as in the morphogenesis of several embryonic structures.
VE:  1 * 100 µG
Artikel-Nr: (PRSI79-875)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 79-875
Lokale Artikelnummer:: PRSI79-875
Beschreibung:   Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 70-624
Lokale Artikelnummer:: PRSI70-624
Beschreibung:   Anti-PMEPA1 Rabbit Polyclonal Antibody
VE:  1 * 50 µl

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 6889
Lokale Artikelnummer:: PRSI6889
Beschreibung:   ABCA7 Antibody: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. The high expression levels of ABCA7 in peripheral leukocytes, thymus, spleen and bone marrow suggests a role in the immune system lipid homeostasis.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 79-424
Lokale Artikelnummer:: PRSI79-424
Beschreibung:   Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 2335P
Lokale Artikelnummer:: PRSI2335P
Beschreibung:   IKK gamma peptide is used for blocking the activity of IKK gamma antibody.
VE:  1 * 50 µG
Artikel-Nr: (PRSI45-954)

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 45-954
Lokale Artikelnummer:: PRSI45-954
Beschreibung:   Anti-DPF1 Goat Polyclonal Antibody
VE:  1 * 100 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 30-201
Lokale Artikelnummer:: PRSI30-201
Beschreibung:   CDH7 is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures.This gene is a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures. Alternative splicing in the 5' UTR of this gene yields variant transcripts encoding the same protein.
VE:  1 * 50 µG

Lieferant:  ProSci Inc.
Hersteller-Artikelnummer:: 4343
Lokale Artikelnummer:: PRSI4343
Beschreibung:   CDNF Antibody: The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6-OHDA)-induced degeneration of dopaminergic neurons in a rat model of Parkinson's disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinson's disease. At least two isoforms of CDNF are known to exist.
VE:  1 * 100 µG
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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