PROSCI
Artikel-Nr:
(PRSIXP-5734-M)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5734-M
Lokale Artikelnummer::
PRSIXP-5734-M
Beschreibung:
Macrophage Inflammatory Protein 1 alpha and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77% and 70% amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation.
VE:
1 * 500 µG
Artikel-Nr:
(PRSI60-444)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-444
Lokale Artikelnummer::
PRSI60-444
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI42-571)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-571
Lokale Artikelnummer::
PRSI42-571
Beschreibung:
Anti-TTC8 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSIXP-5207BT)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5207BT
Lokale Artikelnummer::
PRSIXP-5207BT
Beschreibung:
Anti-CXCL1 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6049)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6049
Lokale Artikelnummer::
PRSI6049
Beschreibung:
SYNPO Antibody: SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-627)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-627
Lokale Artikelnummer::
PRSI33-627
Beschreibung:
Reacts with human CD61, also called Integrin beta 3 (GPIIIa, vitronectin receptor beta chain). It associates with the alphaV-chain (CD51) to form vitronectin receptor, or with the alphaIIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61). The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI28-377)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-377
Lokale Artikelnummer::
PRSI28-377
Beschreibung:
Located on chromosome 11, the BTBD15 gene encodes a BTB (POZ) domain containing 15 protein with unknown function.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-785)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-785
Lokale Artikelnummer::
PRSI25-785
Beschreibung:
DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-210)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-210
Lokale Artikelnummer::
PRSI26-210
Beschreibung:
LAX1 is a single-pass type III membrane protein. It negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI31-036)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-036
Lokale Artikelnummer::
PRSI31-036
Beschreibung:
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-913)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-913
Lokale Artikelnummer::
PRSI25-913
Beschreibung:
SLC6A15 shows structural characteristics of an Na (+) and Cl (-)-dependent neurotransmitter transporter, including 12 transmembrane (TM) domains, intracellular N and C termini, and large extracellular loops containing multiple N-glycosylation sites.SLC6A15 shows structural characteristics of an Na (+) and Cl (-)-dependent neurotransmitter transporter, including 12 transmembrane (TM) domains, intracellular N and C termini, and large extracellular loops containing multiple N-glycosylation sites (Farmer et al., 2000 [PubMed 11112352]).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5553)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5553
Lokale Artikelnummer::
PRSI5553
Beschreibung:
PICALM Antibody: PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery. Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia. PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2. Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-779)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-779
Lokale Artikelnummer::
PRSI26-779
Beschreibung:
KLC3 is a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-200)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-200
Lokale Artikelnummer::
PRSI26-200
Beschreibung:
TMEM9 belongs to the TMEM9 family. It may be involved in intracellular transport.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-317)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-317
Lokale Artikelnummer::
PRSI92-317
Beschreibung:
CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT), a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-016)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-016
Lokale Artikelnummer::
PRSI96-016
Beschreibung:
Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF acidic is a potent growth factor for fibroblasts and endothelial cells. FGF acidic is involved in wound repair, angiogenesis, and development. FGF acidic is secreted from cells via an endoplasmic reticulum/Golgi independent mechanism. The ability of FGF acidic to bind to heparin sulfate is required for its ability to interact with FGF receptors and induce signaling. There are four distinct FGF receptors and each has multiple splice variants. FGF acidic binds with high affinity to many, but not all, FGFRs. Signaling cascades activated through FGF basic binding to FGFR include the ras-raf-MAPK, PLCγ/PKC, and PI3K/Akt pathways.
VE:
1 * 200 µG
Preis auf Anfrage
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