PROSCI
Artikel-Nr:
(PRSI45-859)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-859
Lokale Artikelnummer::
PRSI45-859
Beschreibung:
Anti-SCGB2A2 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI36-170)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-170
Lokale Artikelnummer::
PRSI36-170
Beschreibung:
VASP (vasodilator-stimulated phosphoprotein) is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. VASP is an actin-associated protein involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping proteins. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments and it plays a role in actin-based mobility of Listeria monocytogenes in host cells. It regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. VASP phosphorylation is used to monitor the effect of so-called antiplatelet drugs that reduce platelet reactivity and are used to prevent stent thrombosis, strokes and heart attacks in patients. Phosphorylation of VASP at Ser157 causes a mobility shift in SDS gel electrophoresis from 46 to 50kDa, which has been used as a convenient marker to monitor cyclic nucleotide-dependent protein kinase activity.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI19-091)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-091
Lokale Artikelnummer::
PRSI19-091
Beschreibung:
Anti-RNF212 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI26-773)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-773
Lokale Artikelnummer::
PRSI26-773
Beschreibung:
The exact function of SAMD14 remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI2157P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2157P
Lokale Artikelnummer::
PRSI2157P
Beschreibung:
DR6 peptide is used for blocking the activity of DR6 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3475)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3475
Lokale Artikelnummer::
PRSI3475
Beschreibung:
Caspase-8 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-8 is an initiator caspase that was identified as a member of the Fas/APO-1 death-inducing signaling complex. The adaptor molecule FADD couples procaspase-8 to the Fas receptor death domain; subsequent oligomerization promotes procaspase-8 autoactivation. FLIP, a catalytically inactive caspase-8-like molecule inhibits these interactions and thus can inhibit apoptosis. This antibody will only detect isoform E of caspase-8.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI7437)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7437
Lokale Artikelnummer::
PRSI7437
Beschreibung:
ESR1 Antibody: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ESR1, also known as ER-alpha and ESR2 (ER-beta), contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ESR1 is a widely expressed nuclear protein and serves as a strong activator of estrogen responsive genes (1,2). Phosphorylation of serines 104 and 106, located in the N-terminal transcription activation function-1 domain (AF-1), plays a large role in regulating ER alpha activity.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-825)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-825
Lokale Artikelnummer::
PRSI29-825
Beschreibung:
FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI24-164)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-164
Lokale Artikelnummer::
PRSI24-164
Beschreibung:
Anti-V5 Epitope Tag Recombinant Antibody [Clone: SV5-P-K]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PRSI92-486)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-486
Lokale Artikelnummer::
PRSI92-486
Beschreibung:
Mouse Programmed cell death 1 ligand 1(Cd274,PD-L1), is a member of the growing B7 family of immune proteins.It involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.B7-H1 has been identified as one of two ligands for programmed death1 (PD1), a member of the CD28 family of immunoreceptors. B7-H1 is constitutively expressed in several organs such as heart, skeletal muscle B7-H1 expression is upregulated in a small fraction of activated T and B cells and a much larger fraction of activated monocytes. The costimulatory function of B7-H1 is critical for enhancing maturation and differentiation of T-cells in lymphoid organs.B7-H1 expression is also induced in dendritic cells and keratinocytes after IFN gamma stimulation. Interaction of B7-H1 with PD1 results in inhibition of TCR-mediated proliferation and cytokine production. The B7-H1:PD1 pathway is involved in the negative regulation of some immune responses and may play an important role in the regulation of peripheral tolerance.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4409P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4409P
Lokale Artikelnummer::
PRSI4409P
Beschreibung:
IPR1 peptide is used for blocking the activity of IPR1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI45-826)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-826
Lokale Artikelnummer::
PRSI45-826
Beschreibung:
Anti-LDHC Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-405)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-405
Lokale Artikelnummer::
PRSI79-405
Beschreibung:
NF-κ-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-κ-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI2511P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2511P
Lokale Artikelnummer::
PRSI2511P
Beschreibung:
NOD2 peptide is used for blocking the activity of NOD2 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI31-315)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-315
Lokale Artikelnummer::
PRSI31-315
Beschreibung:
The exact functions of ZADH2 remain unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI45-003)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-003
Lokale Artikelnummer::
PRSI45-003
Beschreibung:
Anti-ADAM8 Goat Polyclonal Antibody
VE:
1 * 100 µG
Preis auf Anfrage
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