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PROSCI
Artikel-Nr:
(PRSI61-584)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-584
Lokale Artikelnummer::
PRSI61-584
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI5023)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5023
Lokale Artikelnummer::
PRSI5023
Beschreibung:
SPG15 Antibody: Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders. Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration. SPG15 is the second gene known to be responsible for ARHSP-TCC in the Italian population. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15. SPG15 encodes a protein containing a FYVE zinc finger binding domain which is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. SPG15 mRNA is widely distributed in human tissues, as well as in rat embryos, suggesting a possible role for this protein during embryonic development. SPG15 co-localizes partially with endoplasmic reticulum and endosome markers, suggesting a role in intracellular trafficking. Multiple isoforms of SPG15 are known to exist.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-783)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-783
Lokale Artikelnummer::
PRSI29-783
Beschreibung:
The function remains unknown.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI42-627)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-627
Lokale Artikelnummer::
PRSI42-627
Beschreibung:
Anti-GRM2 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI29-995)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-995
Lokale Artikelnummer::
PRSI29-995
Beschreibung:
The function remains unknown.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI31-135)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-135
Lokale Artikelnummer::
PRSI31-135
Beschreibung:
TRHR is a receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI31-321)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-321
Lokale Artikelnummer::
PRSI31-321
Beschreibung:
The specific function of this protein remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI38-181)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
38-181
Lokale Artikelnummer::
PRSI38-181
Beschreibung:
Anti-MIA2 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI39-853)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
39-853
Lokale Artikelnummer::
PRSI39-853
Beschreibung:
Rho GTPase-activating protein 22 involved in the signal transduction pathway that has been shown to be important during capillary formation during angiogenesis. It is also anactivator for the RAC1
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5555)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5555
Lokale Artikelnummer::
PRSI5555
Beschreibung:
PRDM16 Antibody: PRDM16 is a zinc finger transcription factor and contains an N-terminal PR domain. The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36, q21)-positive MDS/AML. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Recent studies have shown that PRDM16 normally acts as a Smad3 binding protein that may be important for the development of orofacial structures through modulation of the TGF-beta signaling pathway. Other experiments have indicated that PRDM16 controls a bidirectional cell fate switch between skeletal myoblasts and brown fat cells.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-432)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-432
Lokale Artikelnummer::
PRSI26-432
Beschreibung:
TXNDC13 is a single-pass type I membrane protein. It contains 1 thioredoxin domain. The exact function of TXNDC13 remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-911)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-911
Lokale Artikelnummer::
PRSI29-911
Beschreibung:
SLC1A4 is a transporter for alanine, serine, cysteine, and threonine. It exhibits sodium dependence.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-602)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-602
Lokale Artikelnummer::
PRSI79-602
Beschreibung:
The Itg-Beta3 gene encodes the beta subunit of the platelet membrane adhesive protein receptor complex Itg-Beta3 protein, which belongs to the Integrin class of cell adhesion molecule receptors that share a common heterotrimeric structure with Alpha and Beta subunits. It is a common Beta subunit of the platelet complex and of two other Integrins (Fibronectin and Vitronectin Receptors), which have distinct Alpha subunits. Itg-Beta3 has been implicated in a wide variety of functions, including platelet aggregation and thrombosis and implantation, placentation, angiogenesis, bone remodeling, and tumor progression. Glanzmann Thrombasthenia can result from defects in the genes for either the Itg-Alpha2B or the Itg-Beta3 subunit
VE:
1 * 100 µG
Artikel-Nr:
(PRSI36-269)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-269
Lokale Artikelnummer::
PRSI36-269
Beschreibung:
ANGPTL4 mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorgenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 is a protein consisting of an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain (FLD). Both domains have distinct biological functions. The coiled-coil domain is responsible for the inhibitory effects on lipoprotein lipase (LPL) converting the active form of LPL into an inactive form, and the FLD domain mediates its antiangiogenic functions. The coiled coil and the FLD domains are separated by a short linker that can be cleaved after secretion. ANGPTL4 appears on the cell surface as the full-length form, where it can be released by heparin treatment. ANGPTL4 protein is then proteolytically cleaved by proprotein convertases (PCs), including furin, PC5/6, paired basic amino acid-cleaving enzyme 4, and PC7.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI92-270)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-270
Lokale Artikelnummer::
PRSI92-270
Beschreibung:
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localises in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will result in gastric cancer and prostate cancer.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5963)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5963
Lokale Artikelnummer::
PRSI5963
Beschreibung:
NALP7 Antibody: NOD proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins. NALP7, also known as PYPAF3, a member of the related PYRIN-containing APAF1-like proteins (PYPAFs/NALPs) is thought to play a crucial role in cell proliferation. NALP7 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It is expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. NALP7 inhibits caspase-1-dependent interleukin-1 beta secretion and is a feedback regulator of interleukin-1 beta secretion. Defects in the NALP7 gene are known to cause the formation of a hydatidiform mole (HYDM) and reduce the growth of carcinoma cell lines.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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