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[(tert-Butoxycarbonyl)aminooxy]acetic acid
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[(tert-Butoxycarbonyl)aminooxy]acetic acid
Artikel-Nr:
(PRSI79-988)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-988
Lokale Artikelnummer::
PRSI79-988
Beschreibung:
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI3947P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3947P
Lokale Artikelnummer::
PRSI3947P
Beschreibung:
PKR peptide is used for blocking activity of PKR antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI2285P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2285P
Lokale Artikelnummer::
PRSI2285P
Beschreibung:
LFG peptide is used for blocking the activity of LFG antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-696)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-696
Lokale Artikelnummer::
PRSI27-696
Beschreibung:
PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family. It also activates TGF-beta/SMAD transcriptional responses.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI1150)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
1150
Lokale Artikelnummer::
PRSI1150
Beschreibung:
MADD Antibody: MAP kinase-activating death domain protein (MADD) was initially identified as the type 1 tumor necrosis factor receptor (TNFR1) associated protein though their death domains. Overexpression of MADD activates MAP kinases ERK and JNK and induces the phosphorylation of cytosolic phospholipase A2. MADD shares 98% identity with DENN (for differentially expressed in neoplastic vs. normal cells), which was recently identified as a substrate for c-jun N-terminal kinase 3 (JNK3). MADD has greater than 94% overall identity to a GDP/GTP exchange protein Rab3-GEP. MADD is 87% identical to KIAA0358, a brain protein of unknown function. Identification of MADD as a component of the TNFR1 signaling complex and the similarity between MADD and Rab3-GEP provides a connection between TNFR1 activation and downstream MAP kinase activity through a guanine-nucleotide exchange protein.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI3925)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3925
Lokale Artikelnummer::
PRSI3925
Beschreibung:
Avian Influenza Hemagglutinin 1 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-565)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-565
Lokale Artikelnummer::
PRSI26-565
Beschreibung:
DCP1B may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6921)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6921
Lokale Artikelnummer::
PRSI6921
Beschreibung:
CASK Antibody: CASK (Calcium/calmodulin-dependent serine protein kinase), a conserved multi-domain scaffolding protein, belongs to a MAGUK (membrane-associated guanylate kinase homologs) subfamily and is involved in cell junction organization, tumor suppression and signaling. It is characterized by a novel domain structure that consists of a calcium/calmodulin-dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is ubiquitously expressed and significantly greater in brain where it is thought to be involved in signaling at neuronal synapses. CASK interacts with CASKINs and defects in CASK are the cause of mental retardation X-linked CASK-related.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-682)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-682
Lokale Artikelnummer::
PRSI91-682
Beschreibung:
Phosphatidylinositol 4-Kinase beta (PI4KB) belongs to the PI3/PI4-kinase family and Type III PI4K subfamily. PI4KB contains one PI3K/PI4K domain and one PIK helical domain. It is highly expressed in heart, skeletal muscle, pancreas, testis and ovary,; it is lowly expressed in liver tissue. PI4KB kinase activity can be inhibited by wortmannin, and increased by interacting with NCS1/FREQ. PI4KB phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). In addition, PI4KB may regulate Golgi disintegration/reorganization during mitosis.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI63-510)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-510
Lokale Artikelnummer::
PRSI63-510
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI6091)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6091
Lokale Artikelnummer::
PRSI6091
Beschreibung:
ZIP6 Antibody: The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-214)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-214
Lokale Artikelnummer::
PRSI26-214
Beschreibung:
CLN6 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely CLN6 involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4631)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4631
Lokale Artikelnummer::
PRSI4631
Beschreibung:
SATB1 Antibody: Human special AT-rich sequence-binding protein-1 (SATB1) is a nuclear matrix/scaffold-associated region DNA-binding protein, predominantly expressed in the thymus and pre-B cells. Like its homolog SATB2, SATB1 selectively binds double-stranded, special AT-rich DNA sequences in which one strand exclusively consists of well-mixed A, T, and C nucleotides. SATB1 contains a dimerization domain that shares similarity with the PDZ motif, identified as an indispensable element for high-affinity binding of SATB1 to DNA. SATB1 constitutes a functional nuclear architecture that has a 'cage-like' protein distribution surrounding heterochromatin and regulates gene expression through chromatin remodeling/HDAC (histone deacetylase complex) and transcription factors recruitment. SATB1 functions as a 'genome organizer' essential for proper T-cell development. Recent studies show that SATB1 is necessary for breast cancer cells to become metastatic, and when ectopically expressed in non-metastatic cells, can induce invasive activity in vivo. At least two isoforms of SATB1 are known to exist.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI5285)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5285
Lokale Artikelnummer::
PRSI5285
Beschreibung:
SYPL1 Antibody: The synaptophysin-like protein 1, also known as pantophysin, is a homolog of the neuroendocrine-specific protein synaptophysin, with the highest level of homology across its four transmembrane domains. Unlike synaptophysin however, SYPL1 is ubiquitously expressed and found in small cytoplasmic transport vesicles regardless of their content. SYPL1 is thought to play a multifunctional role in vesicle biogenesis and transport and is a component of adipocyte transport vesicles, and thus may be involved in adipocyte secretion. SYPL1 also interacts with vesicle-associated membrane protein 2 (VAMP-2) in adipocytes and associates with GLUT4-containing vesicles.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-804)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-804
Lokale Artikelnummer::
PRSI79-804
Beschreibung:
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-555)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-555
Lokale Artikelnummer::
PRSI79-555
Beschreibung:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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