PROSCI
Artikel-Nr:
(PRSI79-150)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-150
Lokale Artikelnummer::
PRSI79-150
Beschreibung:
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI22-345)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-345
Lokale Artikelnummer::
PRSI22-345
Beschreibung:
Anti-GM2A Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI45-280)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-280
Lokale Artikelnummer::
PRSI45-280
Beschreibung:
Anti-ARG1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI34-127)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
34-127
Lokale Artikelnummer::
PRSI34-127
Beschreibung:
This mAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI30-214)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-214
Lokale Artikelnummer::
PRSI30-214
Beschreibung:
UST catalyzes the transfer of sulfate to the position 2 of uronyl residues. UST has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. It has no activity toward desulfated N-resulfated heparin.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI61-608)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-608
Lokale Artikelnummer::
PRSI61-608
Beschreibung:
For WB starting dilution is: 1:1000. For FACS starting dilution is: 1:10~50. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI79-198)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-198
Lokale Artikelnummer::
PRSI79-198
Beschreibung:
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI92-044)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-044
Lokale Artikelnummer::
PRSI92-044
Beschreibung:
Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI45-250)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-250
Lokale Artikelnummer::
PRSI45-250
Beschreibung:
Anti-STXBP6 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI34-087)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
34-087
Lokale Artikelnummer::
PRSI34-087
Beschreibung:
PTH/Parathyroid hormone is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterised by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI54-324)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
54-324
Lokale Artikelnummer::
PRSI54-324
Beschreibung:
Anti-ICAM1 Rabbit Monoclonal Antibody [clone: H3]
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI3041)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3041
Lokale Artikelnummer::
PRSI3041
Beschreibung:
PUMA Antibody: Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse. PUMA/bbc3 is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI63-643)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-643
Lokale Artikelnummer::
PRSI63-643
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50. For IF starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI91-571)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-571
Lokale Artikelnummer::
PRSI91-571
Beschreibung:
Leucine-Rich Repeat-Containing Protein 3B (LRRC3B) belongs to the LRRC3 family. LRRC3B is single-pass membrane protein and contains three leucine-rich repeats, one LRRCT domain, and one LRRNT domain. LRR-containing proteins, of which there are greater than 2,000, participate in many important processes, including plant and animal immunity, hormone-receptor interactions, cell adhesion, signal transduction, regulation of gene expression, and apoptosis. A number of microarray expression profiling studies on human cancers have shown that LRRC3B is down-regulated in gastric, breast, colon, testis, prostate and brain cancers, suggesting LRRC3B involvement in carcinogenesis
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-037)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-037
Lokale Artikelnummer::
PRSI96-037
Beschreibung:
AXL Receptor Tyrosine Kinase is also known as Tyrosine-protein kinase receptor UFO, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. AXL contains two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. AXL is highly expressed in metastatic colon tumors. AXL is activated by GAS6-binding and subsequent autophosphorylation. AXL is involved in signal transduction from the extracellular matrix into the cytoplasm by binding growth factors, and thus implicated in the stimulation of cell proliferation.
VE:
1 * 200 µG
Artikel-Nr:
(PRSI92-440)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-440
Lokale Artikelnummer::
PRSI92-440
Beschreibung:
Periostin is a secreted, homodimeric protein that belongs to the periostin family of the FAS1 superfamily of molecules. It is a TGF-beta inducible molecule that serves as both an adhesion molecule and tumour suppressor. It is synthesised by smooth muscle cells, fibroblasts and osteoblasts, as well as in the periosteum and periodontal ligament.
VE:
1 * 50 µG
Preis auf Anfrage
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