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PROSCI
Artikel-Nr:
(PRSI29-976)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-976
Lokale Artikelnummer::
PRSI29-976
Beschreibung:
HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least eleven alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7163)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7163
Lokale Artikelnummer::
PRSI7163
Beschreibung:
DHX36 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI36-229)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-229
Lokale Artikelnummer::
PRSI36-229
Beschreibung:
ANGPTL6 regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism. The serum levels of ANGPTL6 are significantly increased in obese humans, patients with type 2 diabetes mellitus (T2DM), and in metabolic syndrome.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI28-095)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-095
Lokale Artikelnummer::
PRSI28-095
Beschreibung:
VPS24 encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI31-035)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-035
Lokale Artikelnummer::
PRSI31-035
Beschreibung:
Cyclin H regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive carboxyl-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. It is involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI46-125)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-125
Lokale Artikelnummer::
PRSI46-125
Beschreibung:
Anti-PACSIN3 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-977)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-977
Lokale Artikelnummer::
PRSI27-977
Beschreibung:
KIF1C represents a member of the Unc104 subfamily of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1C consists of an amino-terminal motor domain followed by a U104 domain and probably binds to target membranes through carboxyl-terminal sequences.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI5077)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5077
Lokale Artikelnummer::
PRSI5077
Beschreibung:
LRFN4 Antibody: LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN4 are known to exist.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI2051)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2051
Lokale Artikelnummer::
PRSI2051
Beschreibung:
ADAM10 Antibody: Proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha ) contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-alpha , notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease), was recently identified to cleave TNF-alpha , notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM 10, kuzbanian (KUZ), and MADM, respectively. ADAM10 mRNA is expressed in a variety of human and bovine tissues.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI2149P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2149P
Lokale Artikelnummer::
PRSI2149P
Beschreibung:
DRAK2 peptide is used for blocking the activity of DRAK2 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSIXW-7894)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XW-7894
Lokale Artikelnummer::
PRSIXW-7894
Beschreibung:
FUNCTION: Protein kinase that plays an important role in cellular stress response. Activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. Sustained high levels and activity may contribute to conditions such as hypertension and diabetic nephropathy. Mediates cell survival signals, phosphorylates and negatively regulates pro-apoptotic FOXO3A. Phosphorylates NEDD4L, which leads to its inactivation and to the subsequent activation of various channels and transporters such as ENaC, Kv1.3, or EAAT1.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI48-916)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
48-916
Lokale Artikelnummer::
PRSI48-916
Beschreibung:
Anti-XPO1 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-472)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-472
Lokale Artikelnummer::
PRSI28-472
Beschreibung:
Located on chromosome 16, the FLJ31875 gene encodes a hypothetical protein.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6499)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6499
Lokale Artikelnummer::
PRSI6499
Beschreibung:
UPK1B Antibody: Uroplakin-1B (UPK1B) is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. UPK1B is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins and may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-247)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-247
Lokale Artikelnummer::
PRSI25-247
Beschreibung:
PKDREJ is a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a receptor for egg jelly (REJ) domain, a G-protein-coupled receptor proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may play a role in human reproduction.This intronless gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a receptor for egg jelly (REJ) domain, a G-protein-coupled receptor proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may play a role in human reproduction. Alternative splice variants have been described but their biological natures have not been determined.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5529P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5529P
Lokale Artikelnummer::
PRSI5529P
Beschreibung:
RHBDD3 peptide is used for blocking the activity of RHBDD3 antibody.
VE:
1 * 50 µG
Preis auf Anfrage
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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