PROSCI
Artikel-Nr:
(PRSI90-510)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-510
Lokale Artikelnummer::
PRSI90-510
Beschreibung:
Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B, T and dendritic cells, macrophages and endothelial cells. Recent evidence suggests that IL-21 plays a supportive role in the proliferation of T and B cells and influences the cytolytic activity of natural killer cells. IL-21 has been shown to up-regulate genes associated with innate immunity and to inhibit the differentiation of naive T helper cells. IL-21 specifically inhibits IFN-gamma production from developing TH1 cells and is preferentially expressed by TH2 cells. Furthermore IL-21 has been identified as a growth and survival factor for human myeloma cells. IL-21/IL-21R interactions have a unique role in sequentially activating both innate and adaptive immune responses against poorly immunogenic tumours, leading to tumour rejection that is perforin dependent but IFN-gamma independent.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI23-125)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-125
Lokale Artikelnummer::
PRSI23-125
Beschreibung:
Anti-PRKDC Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI6631)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6631
Lokale Artikelnummer::
PRSI6631
Beschreibung:
EPAC1 Antibody: EPAC1, also known as Rap guanine nuclear exchange factor 3 and cAMPGEF-I, is widely expressed but most prominently in brain, heart, kidney, pancreas, spleen, ovary, thyroid and spinal cord. EPAC1 is a cAMP-binding protein with intrinsic guanine nuclear exchange factor activity that couples cAMP production to the activation of Rap, a GTPase belonging to the Ras family. This activation of Rap influences numerous cellular processes such as integrin-mediated cell adhesion, vascular endothelial barrier formation, and cardiac myocyte gap junction formation. Recently, EPAC1 has been suggested to also be involved in the cAMP-dependent regulation of ion channel formation, intracellular Ca++ signalling, ion transporter activity, and exocytosis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI70-506)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
70-506
Lokale Artikelnummer::
PRSI70-506
Beschreibung:
Anti-ATP7B Rabbit Polyclonal Antibody
VE:
1 * 50 µl
Artikel-Nr:
(PRSI7305P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7305P
Lokale Artikelnummer::
PRSI7305P
Beschreibung:
16 amino acids near the amino terminus of human TIAF.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI33-952)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-952
Lokale Artikelnummer::
PRSI33-952
Beschreibung:
HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. [RefSeq].
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI25-491)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-491
Lokale Artikelnummer::
PRSI25-491
Beschreibung:
The exact function of the protein encoded by this gene is not known. However, POGK contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human.The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI60-501)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-501
Lokale Artikelnummer::
PRSI60-501
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI22-166)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-166
Lokale Artikelnummer::
PRSI22-166
Beschreibung:
Anti-DTYMK Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI42-919)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
42-919
Lokale Artikelnummer::
PRSI42-919
Beschreibung:
Anti-SLC5A1 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI61-529)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-529
Lokale Artikelnummer::
PRSI61-529
Beschreibung:
For WB starting dilution is: 1:1000. For IF starting dilution is: 1:10~50. For IHC-P starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI33-304)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-304
Lokale Artikelnummer::
PRSI33-304
Beschreibung:
Recognises a 180-185 kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI31-130)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
31-130
Lokale Artikelnummer::
PRSI31-130
Beschreibung:
The 5-HT1F receptor is present in both human vascular and neuronal tissue. This gene is localized at 3p12.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI45-369)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-369
Lokale Artikelnummer::
PRSI45-369
Beschreibung:
Anti-CBR3 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI71-175)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
71-175
Lokale Artikelnummer::
PRSI71-175
Beschreibung:
Anti-ELOVL5 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7423)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7423
Lokale Artikelnummer::
PRSI7423
Beschreibung:
KHDC1 Antibody: KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability. KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs. KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities.
VE:
1 * 100 µG
Preis auf Anfrage
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