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28 361 results were found
PROSCI
Artikel-Nr:
(PRSI27-217)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-217
Lokale Artikelnummer::
PRSI27-217
Beschreibung:
CCR4 belongs to the G-protein-coupled receptor family. It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. The protein encoded by this gene belongs to the G-protein-coupled receptor family. It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1657 BC071751.1 1-1657
VE:
1 * 50 µG
Artikel-Nr:
(PRSI22-134)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
22-134
Lokale Artikelnummer::
PRSI22-134
Beschreibung:
Anti-ZC3HC1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI50-222)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
50-222
Lokale Artikelnummer::
PRSI50-222
Beschreibung:
EphrinB proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development (Flanagan and Vancerhaeghen, 1998; Dufour et al., 2003; Oike et al., 2002). EphrinB molecules expressed at the membrane surface bind to the EphB family receptors on target cells during cellto cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing EphrinB on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of EphrinB is thought to be a critical component of this reverse signaling event (Palmer et al., 2002). Recent work suggests that phosphorylation of a specific EphrinB residue (Tyr298) plays a key role in EphrinB signaling (Kalo, et al., 2001).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI90-291)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-291
Lokale Artikelnummer::
PRSI90-291
Beschreibung:
Notch signalling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signalling is also involved in cellular processes through-out adulthood. Signalling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-288)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-288
Lokale Artikelnummer::
PRSI25-288
Beschreibung:
The function of SCML1 remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-189)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-189
Lokale Artikelnummer::
PRSI25-189
Beschreibung:
RBBP5 contains 6 WD repeats. It binds preferentially to underphosphorylated retinoblastoma protein. The protein encoded by this gene is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI51-114)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
51-114
Lokale Artikelnummer::
PRSI51-114
Beschreibung:
Survivin is a new inhibitor of apoptosis (IAP) protein. It is expressed in the G2/M phase of the cell cycle in a cycle-regulated manner. The overexpression of surviving in cancer may overcome this apoptotic checkpoint and favor aberrant progression of transformed cells through mitosis.
VE:
1 * 250 µl
Artikel-Nr:
(PRSI50-265)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
50-265
Lokale Artikelnummer::
PRSI50-265
Beschreibung:
Choline acetyltransferase is a neuronal enzyme which catalyzes the reaction between Acetyl CoA and choline resulting in the formation of acetylcholine. It is therefore found primarily in cholinergic neurons making it a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer disease (AD) and Down syndrome (Holt et al. 1999). Decreased choline acetyltransferase activity in particular has been shown in Schizophrenic subjects (Karson et al 1993). It has furthermore been demonstrated that in patients with AD, there are significantly lower levels of cortical ChAT that correlate with severity of the disease as measured by loss of neuropsychological function (Baskin et al. 1999).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI79-103)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-103
Lokale Artikelnummer::
PRSI79-103
Beschreibung:
Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-ζ, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI62-695)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-695
Lokale Artikelnummer::
PRSI62-695
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI19-539)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-539
Lokale Artikelnummer::
PRSI19-539
Beschreibung:
Anti-UBE2F Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI48-918)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
48-918
Lokale Artikelnummer::
PRSI48-918
Beschreibung:
C5L2 is an Anaphylatoxin Receptor. Binding to anaphylatoxins can result in increased triglyceride synthesis, although its precise role in cellular responses has not been determined.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI23-625)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
23-625
Lokale Artikelnummer::
PRSI23-625
Beschreibung:
Anti-PTCD3 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI33-201)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-201
Lokale Artikelnummer::
PRSI33-201
Beschreibung:
Melanocytes produce organelles called melanosomes which produce melanin, the pigment that gives color to skin, hair, eyes, scales and feathers. gp100 was identified in an attempt to clone the gene Tyrosinase, an enzyme required for melanin synthesis. Further testing determined that gp100 is a melanoma-specific protein and is responsible for melanosome maturation, facilitating the transition from amorphous rounded vesicles to fibrillary ellipsoid organelles.
Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. Clone HMB45 gp100 antibody stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. It also stains angiomyolipomas, tumors most commonly associated with the kidney. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. This gp100 antibody does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI29-544)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-544
Lokale Artikelnummer::
PRSI29-544
Beschreibung:
GIPC1/GIPC, GIPC2, and GIPC3 are a family of central PDZ-domain proteins. GIPC2 might play important roles in human gastric cancer through modulation of growth factor signaling or cell adhesion. GIPC1, GIPC2 and GIPC3 might play key roles in carcinogenesis and embryogenesis through modulation of growth factor signaling and cell adhesion.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI98-635)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
98-635
Lokale Artikelnummer::
PRSI98-635
Beschreibung:
Anti-Itgam Rat Monoclonal Antibody [clone: 3A33] (PE (Phycoerythrin))
VE:
1 * 0,1 mg
New Product
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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