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PROSCI
Artikel-Nr:
(PRSI50-151)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
50-151
Lokale Artikelnummer::
PRSI50-151
Beschreibung:
Anti-CALCA Mouse Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(PRSI7419)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7419
Lokale Artikelnummer::
PRSI7419
Beschreibung:
IL-17RA Antibody: Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F (1,2). IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI4747)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4747
Lokale Artikelnummer::
PRSI4747
Beschreibung:
TRIM30 Antibody: TRIM30 belongs to a family of the tripartite motif (TRIM) proteins involved in the regulation of cell proliferation, differentiation, development, oncogenesis, apoptosis and antiviral responses. The TRIM protein family is an expanding family of RING ('really interesting new gene') proteins, also known as RBCC proteins as they contain an RBCC motif, which comprises a RING domain, one or two B-boxes and a predicted coiled-coil region. Studies have shown that some TRIM family members are critical to innate immunity; TRIM5, TRIM19 and TRIM25, for example, have been shown to restrict viral infection. A recent study shows that TRIM30 functions as a negative modulator of the TLR signaling pathway, by targeting TAB2 and TAB3, and contributes to the inhibition of TLR-mediated NF-kappa B activation. The importance of TRIM30 in the attenuation or termination of NF-kappa B activation suggests that targeting of TAB2 and TAB3 by TRIM30alpha may be a mechanism for modulating many types of immune responses.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI2355)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2355
Lokale Artikelnummer::
PRSI2355
Beschreibung:
IRAK-M Antibody: Interleukin-1 (IL-1) and lipopolysaccharide (LPS) induces cellular response through IL-1 receptor (IL-1R) and Toll like receptors (TLR). IL-1 receptor-associated kinase (IRAK and IRAK2) mediates the activation of NF-betaB by IL-1/Toll receptors, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family was recently identified and designated IRAK-M. IRAKs associate with IL-1/Toll receptors after IL-1 or LPS stimulation and the dominant negative mutants of IRAKs inhibit IL-1 or LPS induced NF-betaB activation. Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses to cytokine IL-1 and LPS.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI3491)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3491
Lokale Artikelnummer::
PRSI3491
Beschreibung:
Raptor Antibody: The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. Rapamycin inhibits TOR activity resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation. Raptor (regulatory associated protein of TOR) is a TOR-binding protein essential for TOR signaling in vivo. It acts as a TOR scaffold protein whose binding by TOR substrates is necessary for effective TOR-catalyzed phosphorylation. These substrates include the ribosomal protein S6 kinase (RP S6K) and the eukaryotic initiation factor 4E binding protein 4EBP1, proteins necessary for cell growth and proliferation and responsive to nutrient and mitogen levels. Raptor binds these proteins through a common 5 amino acid TOR-signaling (TOS) motif; mutation of this motif prevents the TOR-dependent phosphorylation of these proteins.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI30-438)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-438
Lokale Artikelnummer::
PRSI30-438
Beschreibung:
SDF2 is believed to be a secretory protein. It has regions of similarity to hydrophilic segments of yeast mannosyltransferases. Its expression is ubiquitous and the gene appears to be relatively conserved among mammals.The protein encoded by this gene is believed to be a secretory protein. It has regions of similarity to hydrophilic segments of yeast mannosyltransferases. Its expression is ubiquitous and the gene appears to be relatively conserved among mammals.
VE:
1 * 100 µG
Artikel-Nr:
(PRSIXP-5164BT)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5164BT
Lokale Artikelnummer::
PRSIXP-5164BT
Beschreibung:
Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3557P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3557P
Lokale Artikelnummer::
PRSI3557P
Beschreibung:
CTRP1 peptide is used for blocking the activity of CTRP1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI35-147)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
35-147
Lokale Artikelnummer::
PRSI35-147
Beschreibung:
Anti-Clostridium Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 1 mL
Artikel-Nr:
(PRSI25-432)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-432
Lokale Artikelnummer::
PRSI25-432
Beschreibung:
The exact function of BUD31 remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI36-186)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-186
Lokale Artikelnummer::
PRSI36-186
Beschreibung:
Bim belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the Bcl-2 protein family (BCL2, BCL2L1/BCL-X(L) and MCL1) and to act as an apoptotic activator, inducing apoptosis and anoikis. Several variants have been identified. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI46-140)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-140
Lokale Artikelnummer::
PRSI46-140
Beschreibung:
Anti-PAX6 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI30-475)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-475
Lokale Artikelnummer::
PRSI30-475
Beschreibung:
PNPLA3 is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes.The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI49-012)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
49-012
Lokale Artikelnummer::
PRSI49-012
Beschreibung:
Anti-UMOD Mouse Monoclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(PRSI45-347)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
45-347
Lokale Artikelnummer::
PRSI45-347
Beschreibung:
Anti-C14ORF68 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-436)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-436
Lokale Artikelnummer::
PRSI27-436
Beschreibung:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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