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PROSCI
Artikel-Nr:
(PRSI62-559)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-559
Lokale Artikelnummer::
PRSI62-559
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI19-348)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
19-348
Lokale Artikelnummer::
PRSI19-348
Beschreibung:
Anti-PIEZO1 Rabbit Polyclonal Antibody
VE:
1 * 50 µl
New Product
Artikel-Nr:
(PRSI62-585)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
62-585
Lokale Artikelnummer::
PRSI62-585
Beschreibung:
For WB starting dilution is: 1:2000. For IHC-P starting dilution is: 1:50~100. For IHC-P starting dilution is: 1:50~100.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSIXW-7168)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XW-7168
Lokale Artikelnummer::
PRSIXW-7168
Beschreibung:
Chicken polyclonal IgY Antibodies against early endosome antigen 1. EEA1 is an early endosome membrane associated protein.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-089)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-089
Lokale Artikelnummer::
PRSI91-089
Beschreibung:
BH3-Interacting Domain Death Agonist (BID) is a member of the Bcl-2 protein family which regulates outer mitochondrial membrane permeability. BID is a pro-apoptotic member that causes cytochrome c to be released from the mitochondria intermembrane space into the cytosol. Interaction of Bid with Bak causes altered mitochondrial membrane permeability. BID contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. It is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent, and also offer a new strategy for the treatment of acute renal failure associated with ischemia-reperfusion. BID receives direct inputs from a key regulator of the cell cycle arrest/DNA repair machinery (ATM), and therefore is an excellent candidate to coordinate genotoxic stress responses and apoptotic cell death. BID is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Deletion of BID inhibits carcinogenesis in the liver, although this genetic alteration promotes tumorigenesis in the myeloid cells. This is likely related to the function of BID to promote cell cycle progression into S phase. BID could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint.
VE:
1 * 0,05 mg
New Product
Artikel-Nr:
(PRSI61-111)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-111
Lokale Artikelnummer::
PRSI61-111
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI92-271)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-271
Lokale Artikelnummer::
PRSI92-271
Beschreibung:
Polyubiquitin-B(UBB) is one of Ubiquitins. Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin is required for ATP-dependent, non-lysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI46-108)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-108
Lokale Artikelnummer::
PRSI46-108
Beschreibung:
Anti-OSBPL2 Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI35-439)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
35-439
Lokale Artikelnummer::
PRSI35-439
Beschreibung:
Anti-Respiratory Syncytial Virus Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-412)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-412
Lokale Artikelnummer::
PRSI33-412
Beschreibung:
This mAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of Alpha heavy chain. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through inter-chain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin A (IgA) is the main protein of the mucosal immune system. It is generated by B-cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobulins. IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobulin receptor (pIgR) for transportation of the molecule to mucosal surfaces. The most common feature of plasmacytomas, and certain non-Hodgkin s lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI26-355)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-355
Lokale Artikelnummer::
PRSI26-355
Beschreibung:
CMAS is an enzyme that catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.
VE:
1 * 50 µG
Artikel-Nr:
(PRSIXW-7666)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XW-7666
Lokale Artikelnummer::
PRSIXW-7666
Beschreibung:
Anti-B2M Chicken Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(PRSI40-537)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
40-537
Lokale Artikelnummer::
PRSI40-537
Beschreibung:
TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant rat TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein.
VE:
1 * 10 µG
Artikel-Nr:
(PRSIXA-1033)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XA-1033
Lokale Artikelnummer::
PRSIXA-1033
Beschreibung:
Anti-NLRP3 Mouse Monoclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-709)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-709
Lokale Artikelnummer::
PRSI33-709
Beschreibung:
This mAb recognises both the free and protein-conjugated (either soluble or cell bound) form of fluorescein or carboxy-fluorescein. Sensitivity of the FITC-anti-FITC system is reportedly similar to that of the biotin-avidin system. In biotin or enzyme-labeled form, this mAb is also suitable for the conversion of fluorescein-labeled detection into immuno-enzymatic assays.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSIPM-4937)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
PM-4937
Lokale Artikelnummer::
PRSIPM-4937
Beschreibung:
XBP-1 Monoclonal Antibody: X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER). Upon sensing unfolded proteins, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA. The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes. Together with other UPR transcription factors such as ATF6, XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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