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4-Cyano-3-fluorobenzoic+acid
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4-Cyano-3-fluorobenzoic+acid
Artikel-Nr:
(217-0808)
Lieferant:
DWK Life Sciences
Hersteller-Artikelnummer::
286130307
Lokale Artikelnummer::
SCOT286130307
Beschreibung:
DURAN®, borosilicate glass 3.3, clear.
VE:
1 * 10 ST
Artikel-Nr:
(BOSSBS-9047R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-A680
Lokale Artikelnummer::
BOSSBS-9047R-A680
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarisation and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid <i>in vitro</i>. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-CY5.5
Lokale Artikelnummer::
BOSSBS-9067R-CY5.5
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-A647
Lokale Artikelnummer::
BOSSBS-9067R-A647
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(MOLEM16616281)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M16616281
Lokale Artikelnummer::
MOLEM16616281
Beschreibung:
4-Methylchinolin
VE:
1 * 25 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(ICNA0520998780)
Lieferant:
MP Biomedicals
Hersteller-Artikelnummer::
0520998780
Lokale Artikelnummer::
ICNA0520998780
Beschreibung:
Triphenylphosphin
VE:
1 * 100 g
Lieferant:
Sigma-Aldrich
Beschreibung:
Bromphenolblau Natriumsalz, Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
Bromphenolblau Natriumsalz ACS
Artikel-Nr:
(HECH40553001)
Lieferant:
GLASWARENFABRIK KARL HECHT
Hersteller-Artikelnummer::
40553001
Lokale Artikelnummer::
HECH40553001
Beschreibung:
Capillary holder, short tube with rubber teat and stopper, length of glass tube approx. 35 mm, Für: Micro pipettes, disposable, End-to-End
VE:
1 * 1 ST
Lieferant:
BOCHEM
Beschreibung:
Stainless steel.
Artikel-Nr:
(EHERC11780000)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C11780000
Lokale Artikelnummer::
EHERC11780000
Beschreibung:
Curcumin
VE:
1 * 0,25 g
Lieferant:
AIR LIQUIDE CRYOTECHNIC
Beschreibung:
Kryogenischer Vorratsbehälter, Rollenuntersatz, nicht magnetisch, Für: Arpege 40/55/75, GT21/26/35/38/40, TP/TR 35/60/100
Artikel-Nr:
(MENAE2695.10)
Lieferant:
MENAI
Hersteller-Artikelnummer::
E2695.10
Lokale Artikelnummer::
MENAE2695.10
Beschreibung:
2-Brom-3',5'-bis(trifluormethyl)acetophenon
VE:
1 * 10 g
Artikel-Nr:
(AMARE905190)
Lieferant:
AMARELL, ARNO
Hersteller-Artikelnummer::
E905190
Lokale Artikelnummer::
AMARE905190
Beschreibung:
Resistant and intensive thermometer for fast temperature indication. With fast-responding stainless steel penetration probe (L×Ø: 125×3,5 mm).
VE:
1 * 1 ST
Artikel-Nr:
(BTIUBNUM1070-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM1070-50
Lokale Artikelnummer::
BTIUBNUM1070-50
Beschreibung:
This antibody recognizes a protein of 35 kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis.Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L( )-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher's Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts.
VE:
1 * 50 µl
Artikel-Nr:
(BOCH591)
Lieferant:
BOCHEM
Hersteller-Artikelnummer::
591
Lokale Artikelnummer::
BOCH591
Beschreibung:
These support clips are coated with ceramic inside.
VE:
1 * 1 ST
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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