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Antikörper
Artikel-Nr:
(USBI041432-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
041432-BIOTIN
Lokale Artikelnummer::
USBI041432-BIOTIN
Beschreibung:
Anti-SATB2 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-3131R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3131R-CY7
Lokale Artikelnummer::
BOSSBS-3131R-CY7
Beschreibung:
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components. Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner. Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace RELA/p65 and associated coregulators from the promoter. Recruited to the NF-kappa-B response element of the CCL2 and IL8 promoters and can displace CREBBP. Present with NF-kappa-B components RELA/p65 and NFKB1/p50 on ERE sequences. Can also act synergistically with NF-kappa-B to activate transcription involving respective recruitment adjacent response elements; the function involves CREBBP. Can activate the transcriptional activity of TFF1. Also mediates membrane-initiated estrogen signaling involving various kinase cascades. Isoform 3 is involved in activation of NOS3 and endothelial nitric oxide production. Isoforms lacking one or several functional domains are thought to modulate transcriptional activity by competitive ligand or DNA binding and/or heterodimerization with the full length receptor. Essential for MTA1-mediated transcriptional regulation of BRCA1 and BCAS3. Isoform 3 can bind to ERE and inhibit isoform 1.
VE:
1 * 100 µl
Artikel-Nr:
(USBII1904-63A)
Lieferant:
US Biological
Hersteller-Artikelnummer::
I1904-63A
Lokale Artikelnummer::
USBII1904-63A
Beschreibung:
Anti-IgG Donkey Polyclonal Antibody
VE:
1 * 1 mg
Artikel-Nr:
(BOSSBS-2571R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2571R-A750
Lokale Artikelnummer::
BOSSBS-2571R-A750
Beschreibung:
Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.
VE:
1 * 100 µl
Artikel-Nr:
(USBI127617)
Lieferant:
US Biological
Hersteller-Artikelnummer::
127617
Lokale Artikelnummer::
USBI127617
Beschreibung:
Anti-GSTT2 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(USBI040236-APC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040236-APC
Lokale Artikelnummer::
USBI040236-APC
Beschreibung:
Anti-POF1B Rabbit Polyclonal Antibody (APC (Allophycocyanin))
VE:
1 * 200 µl
Artikel-Nr:
(AVIVARP35801_P050)
Lieferant:
Aviva Systems Biology
Hersteller-Artikelnummer::
ARP35801_P050
Lokale Artikelnummer::
AVIVARP35801_P050
Beschreibung:
Anti-TRIM16 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-1557G-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1557G-CY5
Lokale Artikelnummer::
BOSSBS-1557G-CY5
Beschreibung:
Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
VE:
1 * 100 µl
Artikel-Nr:
(USBI138096)
Lieferant:
US Biological
Hersteller-Artikelnummer::
138096
Lokale Artikelnummer::
USBI138096
Beschreibung:
Anti-Lymphocyte Rabbit Polyclonal Antibody
VE:
1 * 20 mg
Artikel-Nr:
(USBIT0291-91C)
Lieferant:
US Biological
Hersteller-Artikelnummer::
T0291-91C
Lokale Artikelnummer::
USBIT0291-91C
Beschreibung:
Anti-TAB3 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(USBI043578-FITC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
043578-FITC
Lokale Artikelnummer::
USBI043578-FITC
Beschreibung:
Anti-UGT1A1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
VE:
1 * 200 µl
Artikel-Nr:
(USBI042703)
Lieferant:
US Biological
Hersteller-Artikelnummer::
042703
Lokale Artikelnummer::
USBI042703
Beschreibung:
Anti-TCHP Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-10521R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10521R-A680
Lokale Artikelnummer::
BOSSBS-10521R-A680
Beschreibung:
Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7084R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7084R-A750
Lokale Artikelnummer::
BOSSBS-7084R-A750
Beschreibung:
Defects in NOD2 are the cause of sarcoidosis early-onset (EOS) . EOS is a form of sarcoidosis manifesting in children younger than 4 years of age. Sarcoidosis is an idiopathic, systemic, inflammatory disease characterised by the formation of immune granulomas in involved organs. Granulomas predominantly invade the lungs and the lymphatic system, but also skin, liver, spleen, eyes and other organs may be involved. Early-onset sarcoidosis is quite rare and has a distinct triad of skin, joint and eye disorders, without apparent pulmonary involvement. Compared with an asymptomatic and sometimes naturally disappearing course of the disease in older children, early-onset sarcoidosis is progressive and in many cases causes severe complications, such as blindness, joint destruction and visceral involvement.
VE:
1 * 100 µl
Artikel-Nr:
(USBIM9520-21A)
Lieferant:
US Biological
Hersteller-Artikelnummer::
M9520-21A
Lokale Artikelnummer::
USBIM9520-21A
Beschreibung:
Anti-Muscarinic Receptor M3 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(USBI124194)
Lieferant:
US Biological
Hersteller-Artikelnummer::
124194
Lokale Artikelnummer::
USBI124194
Beschreibung:
Anti-CA9 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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