(2-Methyl-1H-imidazol-4-yl)methanol
Artikel-Nr:
(PRSI92-699)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-699
Lokale Artikelnummer::
PRSI92-699
Beschreibung:
Tumour necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumour necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by cells of the human immune system, is broadly expressed by cells of the human immune system, including activated CD8+ and CD4+ T cells, activated natural killer (NK) cells, follicular dendritic cells (FDCs) and monocytes. CD137 has diverse roles in the immune response, the one key function is to promote the survival of both T cells and dendritic cells by binding the cognate ligand CD137L (4-1BBL).
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-292)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-292
Lokale Artikelnummer::
PRSI92-292
Beschreibung:
Glia maturation factor beta (GMFB) contains a ADF-H domain,which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.
VE:
1 * 50 µG
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Gram’s crystal violet solution, also known as gentian violet or hexamethyl pararosaniline, is a basic, cationic, acidotropic aminoarylmethane dye. It is a hexa-N-methylated triaminotriphenylmethane with a moderately sized lipophilic cation and a slightly nonplanar conjugated system. It is used in bacteriology as the primary stain in Gram staining to differentiate Gram-positive and Gram-negative bacteria. It is known to possess antibacterial and antifungal properties.
Artikel-Nr:
(BOSSBS-0735R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0735R-A750
Lokale Artikelnummer::
BOSSBS-0735R-A750
Beschreibung:
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (By similarity). Cooperates with Wnt-1 in mouse mammary tumor virus-induced murine mammary tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1429R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1429R-A680
Lokale Artikelnummer::
BOSSBS-1429R-A680
Beschreibung:
GAI3 is the a subunit of inhibitory trimeric G protein (Gi), which inhibits adenylate cyclase once its G protein coupled receptors (GPCR) such as a2 adrenergic receptors are activated. GAI3 can be inactivated by pertussis toxin. Guanine nucleotide binding proteins are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor regulated K(+) channels.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0735R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0735R-A680
Lokale Artikelnummer::
BOSSBS-0735R-A680
Beschreibung:
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (By similarity). Cooperates with Wnt-1 in mouse mammary tumor virus-induced murine mammary tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0735R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0735R-CY5.5
Lokale Artikelnummer::
BOSSBS-0735R-CY5.5
Beschreibung:
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (By similarity). Cooperates with Wnt-1 in mouse mammary tumor virus-induced murine mammary tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3654R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3654R-CY3
Lokale Artikelnummer::
BOSSBS-3654R-CY3
Beschreibung:
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11340R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11340R-CY3
Lokale Artikelnummer::
BOSSBS-11340R-CY3
Beschreibung:
The regulated translation of messenger RNA is essential for cell-cycle progression, establishment of the body plan during early development and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, one mechanism of controlling translation, is driven by cytoplasmic polyadenylation element binding proteins, called CPEBs. CPEB3 (cytoplasmic polyadenylation element binding protein 3) is a 698 amino acid protein that contains two RNA recognition motif (RRM) domains and, like other CPEB proteins, may play a role in the maturation of the central nervous system. CPEB3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7970R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7970R
Lokale Artikelnummer::
BOSSBS-7970R
Beschreibung:
ARS2(Arsenite resistance protein 2) confers arsenite resistance. The protein belongs to the ARS2 family. Arsenic is a human carcinogen whose mechanism of action is unknown. The arsenite acts as a comutagen by interfering with DNA repair. Two genes, ASR1(Arsenite resistance protein 1) and ASR2 (Arsenite resistance protein 2), confer arsenite resistance to arsenite-sensitive cells. ASR1 shows almost complete homology with the rat fau gene, a tumor suppressor gene which contains a ubiquitin like region fused to S30 ribosomal protein. Arsenite inhibits ubiquitin dependent proteolysis. The tumor suppressor fau gene product or some other aspect of the ubiquitin system may be a target for arsenic toxicity and that disruption of the ubiquitin system may contribute to the genotoxicity and carcinogenicity of arsenite.
VE:
1 * 100 µl
Artikel-Nr:
(EDVO270)
Lieferant:
EDVOTEK
Hersteller-Artikelnummer::
270
Lokale Artikelnummer::
EDVO270
Beschreibung:
This experiment introduces students to the principles of antigen-antibody interactions by using the Ouchterlony procedure. Antibodies and antigens form complexes that precipitate, making it possible to assay antibody-antigen systems. The binding interaction results in the formation of a white precipitate after diffusion in agarose.
VE:
1 * 1 ST
Artikel-Nr:
(HACH1411100)
Lieferant:
Hach
Hersteller-Artikelnummer::
1411100
Lokale Artikelnummer::
HACH1411100
Beschreibung:
Maintaining safe water conditions and to protect against system corrosion by control of chlorine and pH. The free and total chlorine and pH test kit provides more accuracy than test kits using colour cubes or step-wise comparators.
VE:
1 * 1 KIT
Artikel-Nr:
(PRSI90-306)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-306
Lokale Artikelnummer::
PRSI90-306
Beschreibung:
Flagellin is the subunit protein which polymerises to form the filaments of bacterial flagella. It activates the innate immune system through the receptor Toll-like Receptor 5 (TLR5) or the intracellular NLRC4 protein. The Flagellin (NLRC4 Mutant)(rec. ) is only detected by TLR5 not by NLRC4.
VE:
1 * 10 µG
Artikel-Nr:
(BOSSBS-11990R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11990R-CY5
Lokale Artikelnummer::
BOSSBS-11990R-CY5
Beschreibung:
The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50% of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes, which may modulate the efficiency of insulin signal transduction. SIK is activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-α and CAB39.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11340R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11340R-A488
Lokale Artikelnummer::
BOSSBS-11340R-A488
Beschreibung:
The regulated translation of messenger RNA is essential for cell-cycle progression, establishment of the body plan during early development and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, one mechanism of controlling translation, is driven by cytoplasmic polyadenylation element binding proteins, called CPEBs. CPEB3 (cytoplasmic polyadenylation element binding protein 3) is a 698 amino acid protein that contains two RNA recognition motif (RRM) domains and, like other CPEB proteins, may play a role in the maturation of the central nervous system. CPEB3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11340R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11340R-A555
Lokale Artikelnummer::
BOSSBS-11340R-A555
Beschreibung:
The regulated translation of messenger RNA is essential for cell-cycle progression, establishment of the body plan during early development and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, one mechanism of controlling translation, is driven by cytoplasmic polyadenylation element binding proteins, called CPEBs. CPEB3 (cytoplasmic polyadenylation element binding protein 3) is a 698 amino acid protein that contains two RNA recognition motif (RRM) domains and, like other CPEB proteins, may play a role in the maturation of the central nervous system. CPEB3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.
VE:
1 * 100 µl
Preis auf Anfrage
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