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(Phenylthio)essigs\u00E4ure
Artikel-Nr:
(BOSSBS-13536R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13536R-A488
Lokale Artikelnummer::
BOSSBS-13536R-A488
Beschreibung:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13536R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13536R-A350
Lokale Artikelnummer::
BOSSBS-13536R-A350
Beschreibung:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
VE:
1 * 100 µl
Lieferant:
Bernd Kraft
Beschreibung:
Natriumacetat 400 g/l in wässriger Lösung analytisches Reagens
Artikel-Nr:
(SIAL241245-100G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
241245-100G
Lokale Artikelnummer::
SIAL241245-100G
Beschreibung:
Natriumacetat ≥99,0% ACS
VE:
1 * 100 g
Lieferant:
Bernd Kraft
Beschreibung:
Magnesiumacetat Tetrahydrat, reinst
Lieferant:
Sigma-Aldrich
Beschreibung:
Bariumacetat, Sigma-Aldrich®
Lieferant:
Honeywell Chemicals
Beschreibung:
Ethylacetat ≥99,0% (durch GC), Laborreagens
Lieferant:
Honeywell Chemicals
Beschreibung:
Bariumacetat ≥99%, Puriss. p.a. ACS, Fluka™
Artikel-Nr:
(BOSSBS-13536R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13536R
Lokale Artikelnummer::
BOSSBS-13536R
Beschreibung:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Natriumacetat Trihydrat 99.5% zur Analyse
Lieferant:
LONZA
Beschreibung:
EDTA Dinatriumsalz-Lösung 0.5 M, AccuGENE®
Lieferant:
FLUOROCHEM
Beschreibung:
3-Acetoxybenzaldehyd
Lieferant:
Alfa Aesar
Beschreibung:
Ester of dimethylethanolamine and 4-chlorophenoxyacetic acid.
Artikel-Nr:
(A1691.1000)
Lieferant:
PanReac AppliChem
Hersteller-Artikelnummer::
A1691.1000
Lokale Artikelnummer::
APLIA1691.1000
Beschreibung:
50x Lösung aus 20 M Tris, 1 M Eisessigsäure und 0.5 mM EDTA-Na2; pH 8,5 ±0,2.
VE:
1 * 1 L
Lieferant:
Sigma-Aldrich
Beschreibung:
Magnesiumacetat Tetrahydrat, Sigma-Aldrich®
Lieferant:
Alfa Aesar
Beschreibung:
Dibenzothiophen ≥98%
Preis auf Anfrage
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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