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Proteine und Peptide
Artikel-Nr:
(PRSI90-420)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-420
Lokale Artikelnummer::
PRSI90-420
Beschreibung:
CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. CD160-Fc fusion protein targets a novel costimulatory pathway and prolongs allograft survival.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI90-115)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-115
Lokale Artikelnummer::
PRSI90-115
Beschreibung:
FGF-23 (Fibroblast growth factor 23) is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralisation. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
VE:
1 * 10 µG
Artikel-Nr:
(PRSI7391P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7391P
Lokale Artikelnummer::
PRSI7391P
Beschreibung:
19 amino acids near the carboxy terminus of human AKT1S1.
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Bone morphogenetic protein 2 (BMP-2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Active BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7. BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration.
Artikel-Nr:
(PRSI96-193)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-193
Lokale Artikelnummer::
PRSI96-193
Beschreibung:
Contactin-2 is also known as CNTN2, TAX1 (transiently-expressed axonal glycoprotein), TAG1 (transient axonal glycoprotein), and axonin-1, and is a member of the immunoglobulin superfamily. CNTN2 consists of six Ig-like domains and four fibronectin type III domains, and is anchored to the membrane by glycosylphosphatidylinositol (GPI), whereas the soluble form can be released by a GPI-specific phospholipase. As a neural cell adhesion molecule expressed by a subset of neuronal populations in the developing CNS and PNS, CNTN2 mediates cell-cell interactions either via homophilic, or heterophilic contacts with various adhesion molecules including NgCAM, NrCAM, NCAM and neurocan. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI91-185)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-185
Lokale Artikelnummer::
PRSI91-185
Beschreibung:
Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression reduce of ANXA2 is associated with osteosarcoma metastases. ANXA2 functions as an autocrine factor, it can increases osteoclast formation and bone resorption. ANXA2 is involved in muscular dystrophies. In humans, the up-regulation of ANXA2 is related with colon adenocarcinoma cell differentiation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-892)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-892
Lokale Artikelnummer::
PRSI91-892
Beschreibung:
Mouse vascular endothelial growth factor D, (VEGFD) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. VEGFD is a secreted protein and highly expressed in fetal and adult lung. It undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3 receptors. The structure and function of this protein is similar to VEGFC. VEGFD is growth factor which active in angiogenesis, lymphangiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3045P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3045P
Lokale Artikelnummer::
PRSI3045P
Beschreibung:
p53DINP1 peptide is used for blocking the activity of p53DINP1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7051P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7051P
Lokale Artikelnummer::
PRSI7051P
Beschreibung:
TNFAIP2 peptide is used for blocking the activity of TNFAIP2 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-588)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-588
Lokale Artikelnummer::
PRSI91-588
Beschreibung:
Human EN-RAGE belongs to the S100/calgranulin superfamily. There are at least 21 different S100 proteins and the protein is 100% soluble in ammonium sulfate at neutral pH. S100 proteins play a role in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response.Human EN-RAGE is characterized by two EF-hand calcium-binding motifs, zinc- and copper-binding protein.S100A12 is a disulfide-linked homodimer and the interface between the two subunits is composed mostly of hydrophobic residues.Its proinflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. EN-RAGE acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER). Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leading to production of proinflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1. It also acts as a monocyte and mast cell chemoattractant. Moreover, it can stimulate mast cell degranulation and activation which generates chemokines, histamine and cytokines inducing further leukocyte recruitment to the sites of inflammation. It can inhibit the activity of matrix metalloproteinases; MMP2, MMP3 and MMP9 by chelating Zn2+from their active sites.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6183P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6183P
Lokale Artikelnummer::
PRSI6183P
Beschreibung:
VPS39 peptide is used for blocking the activity of VPS39 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-276)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-276
Lokale Artikelnummer::
PRSI92-276
Beschreibung:
FKBP3 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-698)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-698
Lokale Artikelnummer::
PRSI96-698
Beschreibung:
Signal-regulatory protein gamma (SIRPG or SIRP-gamma) is also known as CD172 antigen-like family member B (CD172g), Signal-regulatory protein beta-2 (SIRPB2), is a single-pass type I membrane protein. SIRPG is expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. SIRPG interacts with CD47. On binding with CD47, CD172g mediates cell-cell adhesion.
VE:
1 * 100 µG
Lieferant:
Alfa Aesar
Beschreibung:
Trypsin inhibitor
Artikel-Nr:
(PRSI96-142)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-142
Lokale Artikelnummer::
PRSI96-142
Beschreibung:
CD9 antigen is also known as tetraspanin-29 (TSPAN29), 5H9 antigen, Leukocyte antigen MIC3 (MIC3), Motility-related protein, is a multi-pass membrane protein which belongs to the tetraspanin (TM4SF) family or the transmembrane 4 superfamily. CD9 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. TSPAN29 is found on the surface of exosomes. MIC3 Involved in platelet activation and aggregation, regulates paranodal junction formation and also Involved in cell adhesion, cell motility and tumor metastasis. CD9 antigen also seems to be a key part in the egg-sperm fusion during mammalian fertilization.
VE:
1 * 20 µG
Artikel-Nr:
(PRSI91-388)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-388
Lokale Artikelnummer::
PRSI91-388
Beschreibung:
Apolipoprotein H (ApoH) is a 50 kDa variably glycosylated member of the complement control superfamily of proteins. Human ApoH is a major phospholipid binding protein and an important component to measure in the assessment of anti-phospholipid syndrome. Hepatocyte-derived ApoH binds to negatively charged phospholipids . It circulates as a component of lipoprotein particles and as a lipid-free serum protein. Human ApoH is also more specific than anti-cardiolipin antibodies and its presence correlates better with thrombotic risk. Mature human ApoH shares 76% and 82% aa sequence identity with mouse and rat ApoH.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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