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Proteine und Peptide
Artikel-Nr:
(PRSI6929P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6929P
Lokale Artikelnummer::
PRSI6929P
Beschreibung:
VAMP7 peptide is used for blocking the activity of VAMP7 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-048)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-048
Lokale Artikelnummer::
PRSI90-048
Beschreibung:
Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38 (MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5215P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5215P
Lokale Artikelnummer::
PRSI5215P
Beschreibung:
SHOC2 peptide is used for blocking the activity of SHOC2 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-539)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-539
Lokale Artikelnummer::
PRSI90-539
Beschreibung:
Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilisaion of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/cKit to trigger receptor dimerisaion and signalling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-580)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-580
Lokale Artikelnummer::
PRSI91-580
Beschreibung:
Alpha-1-antitrypsin 1-3(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. Mouse SERPIN A1 is a serine protease inhibitor whose targets include elastase,plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema orliver disease. Several transcript variants encoding the same protein have been found for this gene.
VE:
1 * 50 µG
Lieferant:
Alfa Aesar
Beschreibung:
Protease inhibitor that acts on pepsin, renin and cathepsin D.
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor beta (TGF-β) family and is made by the placenta and cardiovascular tissues. GDF-15 regulates inflammatory and apoptotic pathways during cellular stress and injury. GDF-15 is emerging as a biomarker of early heart disease, such that increased levels of circulating GDF-15 are associated with an increased risk of developing heart failure.
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Neurotrophin-3 (NT-3) is an important member of the nerve growth factor (NGF) family of proteins. NT-3 promotes the growth, survival, and differentiation of neurons and synapses in the peripheral and central nervous systems. The receptor tyrosine kinase TrkC exclusively binds in high-affinity to NT-3. NT-3 also signals through the receptor tyrosine kinase TrkB, and through the low affinity nerve growth factor receptor (LNGFR).
Artikel-Nr:
(PRSI7057P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7057P
Lokale Artikelnummer::
PRSI7057P
Beschreibung:
VNN3 peptide is used for blocking the activity of VNN3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-086)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-086
Lokale Artikelnummer::
PRSI90-086
Beschreibung:
ANGPTL3 (Angiopoietin-like protein 3) regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI90-300)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-300
Lokale Artikelnummer::
PRSI90-300
Beschreibung:
FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice. FLT3L induces the mobilisation of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3L is crucial for steady-state pDC (plasmacytoid dendritic cells) and cDC (classical dendritic cells) development. Deficiency of FLT3L causes a dramatic decrease in DC numbers, whereas increasing its availability increase in DC numbers.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI92-643)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-643
Lokale Artikelnummer::
PRSI92-643
Beschreibung:
Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Mesothelin plays an important role in cell survival, proliferation, migration, invasion, tumour progression, and resistance to chemotherapy. The overexpression of mesothelin can activate NF-κB and signal transducer and activator of transcription 3 (Stat3), inhibit apoptotic signalling and TNF- alpha-induced apoptosis, and accelerate the G1–S transition. Mesothelin is also found overexpressed in various cancers, including malignant mesothelioma, pancreatic or ovarian carcinoma, sarcomas and in some gastrointestinal or pulmonary carcinomas. As a result of its limited expression in normal tissues, mesothelin has been reported as an ideal tumour-associated marker for the development of targeted therapy.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5245P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5245P
Lokale Artikelnummer::
PRSI5245P
Beschreibung:
H1N1 Neuraminidase peptide is meant to be used as a positive control in ELISA applications to detect either Seasonal or Swine-Origin Influenza A antibody.
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Resistin-like molecule-alpha (RELM-α) is a member of the RELM family of secreted proteins containing conserved C-terminus cysteines. The RELM family consists of Resistin (FIZZ3), RELM-α (FIZZ1), RELM-β (FIZZ2), and RELM-γ (FIZZ4). RELM-α and Resistin are secreted by adipocytes, unlike RELM-β which is secreted by gastrointestinal epithelial cells, and RELM-γ which is expressed by peripheal blood granulocytes and bone marrow cells.
Artikel-Nr:
(PRSI7159P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7159P
Lokale Artikelnummer::
PRSI7159P
Beschreibung:
18 amino acids near the amino terminus of human SIDTR2.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-023)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-023
Lokale Artikelnummer::
PRSI96-023
Beschreibung:
The bone morphogenetic protein receptor, type IA is also known as BMPR1A or ALK3 is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 290). The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. Alk3-mediated BMP signaling in AV endocardial/mesenchymal cells plays a central role during cushion morphogenesis.
VE:
1 * 200 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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