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Proteine und Peptide
Artikel-Nr:
(PRSI91-684)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-684
Lokale Artikelnummer::
PRSI91-684
Beschreibung:
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) is a member of the immunoglobulin superfamily A and CEA family. CEACAM7 localizes to the cell membrane and contains one Ig-like C2-type domain and one Ig-like V-type domain. The expression of CEACAM7 is significantly decreased in rectal cancer. Differences in CEACAM7 expression levels between long-term survivors and those with recurrent disease introduce a potential tumor marker to define a subset of patients who benefit most from adjuvant therapy.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-723)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-723
Lokale Artikelnummer::
PRSI91-723
Beschreibung:
Uroplakin-2 is a single-pass type I membrane protein that belongs to the uroplakin-2 family. Uroplakin-2 is a component of the asymmetric unit membrane (AUM) and expressed in the ureter, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. Uroplakin-2 forms heterodimer with UPK1A that is necessary for exiting out of the endoplasmic reticulum (ER). Uroplakin-2 may play an important role in regulating the assembly of the AUM. AUM is believed to strengthen the urothelium by preventing cell rupture during bladder distention.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI40-613)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
40-613
Lokale Artikelnummer::
PRSI40-613
Beschreibung:
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains. Recombinant rat VEGF is a 38.5 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI2161P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2161P
Lokale Artikelnummer::
PRSI2161P
Beschreibung:
BCL-10 peptide is used for blocking the activity of BCL-10 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5637P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5637P
Lokale Artikelnummer::
PRSI5637P
Beschreibung:
DCLK3 peptide is used for blocking the activity of DCLK3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-120)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-120
Lokale Artikelnummer::
PRSI92-120
Beschreibung:
Gamma-Synuclein (SNCG) is a member of the Synuclein protein family. Gamma-Synuclein is mostly expressed in the peripheral nervous system and retina. Gamma-Synuclein plays a role in neurofilament network integrity and may be involved in modulating axonal architecture during development and in the adult. In addition, it may also function in modulating the keratin network in skin. SNCG expression in breast tumours has been as a marker for tumour progression. SNCG is also believed to be involved in the pathogenesis of neurodegenerative diseases.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-314)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-314
Lokale Artikelnummer::
PRSI91-314
Beschreibung:
Epithelial Cell Adhesion Molecule (EpCAM) is a signal type I transmembrane glycoprotein that belongs to the EPCAM family. EpCAM is composed of an extracellular domain with one thyroglobulin type-1 domain, a transmembrane domain and a cytoplasmic domain. EpCAM is found on the surface of adenocarcinoma, but not on mesodermal or neural cell membranes. The EpCAM molecule has been shown to function as a homophilic Ca2+ independent adhesion molecule. It may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium as an immunological barrier providing the first line of defense against infection. Defects in EPCAM are a cause of hereditary non-polyposis colorectal cancer type 8 (HNPCC8) and diarrhea type 5 (DIAR5). EpCAM plays a role in embryonic stem cells proliferation and differentiation; it up-regulates the expression of FABP5, MYC and Cyclin A and Cyclin E. It is highly and selectively expressed by undifferentiated embryonic stem cells.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-129)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-129
Lokale Artikelnummer::
PRSI90-129
Beschreibung:
FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI90-324)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-324
Lokale Artikelnummer::
PRSI90-324
Beschreibung:
Betatrophin (RIFL; Lipasin; Angiopoietin-like protein 8 (ANGPTL8)) is a newly discovered secreted protein of 198 aa that was proposed to promote beta cell proliferation and improve glucose tolerance in mice. Betatrophin may also function in inhibition of lipase activity and on serum triglyceride regulation. Betatrophin is expressed in the liver and in white and brown adipose tissue of mice. In humans, betatrophin is found to be predominantly expressed in the liver. Betatrophin levels are reduced by fasting and are elevated upon insulin resistance and during pregnancy. Betatrophin, according to preliminary data could bind to the macrophage receptor Marco and also to RTN4R, a neuronal receptor. Recently, a study using ANGPTL8 KO mice showed that ANGPTL8/Betatrophin does not play a role in beta cell proliferation nor in glycemic control as previously thought, but regulates plasma triglyceride levels.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI91-445)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-445
Lokale Artikelnummer::
PRSI91-445
Beschreibung:
Neuroligin-1 is a single-pass type I transmembrane protein which belongs to the type-B Carboxylesterase/Lipase family. Neuroligins are cell-adhesion molecules located at the postsynaptic side of the synapse. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses. Neurexins and Neuroligins are cell adhesion molecules present in excitatory and inhibitory synapses, and they are required for correct neuron network function. These proteins are found at the presynaptic and postsynaptic membranes. Neuroligin-1 is a neuronal cell surface protein which is thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. It seems to play role in formation or maintenance of synaptic junctions. It triggers the de novo formation of presynaptic structures and may be involved in specification of excitatory synapses.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7425P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7425P
Lokale Artikelnummer::
PRSI7425P
Beschreibung:
19 amino acids near the carboxy terminus of FGFR3.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4217P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4217P
Lokale Artikelnummer::
PRSI4217P
Beschreibung:
Strep-tag II peptide is used for blocking the activity of strep-tag II antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7227P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7227P
Lokale Artikelnummer::
PRSI7227P
Beschreibung:
15 amino acids near the center of human CCL4.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-048)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-048
Lokale Artikelnummer::
PRSI91-048
Beschreibung:
Human Chemokine (C-C Motif) Ligand 3 (CCL3) is a small cytokine belonging to the CC chemokine family. CCL3 is primarily expressed in T cells, B cells, and monocytes after antigen or mitogen stimulation. CCL3 exhibits chemoattractive and adhesive effects on lymphocytes. CCL3 exerts multiple effects on hematopoietic precursor cells and inhibits the proliferation of hematopoietic stem cells in vitro as well as in vivo. CCR1 and CCR5 have been identified as functional receptors for CCL3.
VE:
1 * 50 µG
Lieferant:
Alfa Aesar
Beschreibung:
Melanocyte-stimulating hormone-release inhibiting factor
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Acidic fibroblast growth factor (FGF-acidic), also known as FGF-1, is a potent inducer of DNA synthesis, cell proliferation, and has chemotactic activities. FGF-acidic regulates cardiogenesis through protein kinase C signaling. FGF-acidic also functions as an insulin sensitiser and mediates adipose tissue remodeling. High serum levels of FGF-acidic are associated with type 2 diabetes mellitus (T2DM), suggesting a pathogenic role of FGF-acidic during T2DM.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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