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Proteine und Peptide
Artikel-Nr:
(PRSI92-380)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-380
Lokale Artikelnummer::
PRSI92-380
Beschreibung:
CD99 Antigen-Like Protein 2 (CD99L2) belongs to the CD99 family. CD99L2 is a single-pass type I membrane protein and expressed in many tissues, with low expression in thymus. CD99L2 plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3647P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3647P
Lokale Artikelnummer::
PRSI3647P
Beschreibung:
TLR5 peptide is used for blocking the activity of TLR5 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-502)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-502
Lokale Artikelnummer::
PRSI91-502
Beschreibung:
Anterior Gradient Protein 2(AG-2) and Anterior Gradient Protein 3 (AG-3) are human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan (hAG-3 protein). AG-3 could serve as a prognostic marker for survival in patients with low grade and high grade serous ovarian carcinomas.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-639)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-639
Lokale Artikelnummer::
PRSI92-639
Beschreibung:
NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor-binding protein (IGFBP) domain, von Willebrand type C (VWC) domain, thrombospondin-1 (TSP-1) domain, and C-terminal (CT) domain (absent in CCN5). By specific interactions with these domains, CCN proteins modulate multiple signalling pathways including BMPs, Wnt, TGFs, Notch and integrins to regulate cell proliferation, differentiation, adhesion, migration, angiogenesis, and survival. CCN3 is firstly characterised as a promoter of progenitor activity of human hematopoietic stem cells, as knockdown of CCN3 can abrogate the function of primitive progenitors. Recent studies showed that CCN3 is also actively involved in the process of wound healing. CCN3 is highly expressed in granulation tissues of cutaneous wounds and capable of inducing synthetic responses of fibroblasts.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-421)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-421
Lokale Artikelnummer::
PRSI91-421
Beschreibung:
Ephrin-B2 is a type I transmembrane protein and belongs the Ephrin family. It binds to the receptor tyrosine kinases, such as EPHA4, EPHB4 and EPHA3. Ephrin-B2 has been implicated in mediating developmental events, especially in the nervous system, erythropoiesis and tumour metastasis. Ligation of Ephrin-B2 with complementary EphB receptors on adjacent cells results in a combination of forward (EphB receptors) and reverse (Ephrin-B2) signalling, which is central to tissue development and remodelling functions. In addition, Ephrin-B2 may play a role in constraining the orientation of longitudinally projecting axons.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-200)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-200
Lokale Artikelnummer::
PRSI92-200
Beschreibung:
Mouse Interleukin 33 (IL-33) is a proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1. BindingIL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces the expression of IL-4, IL-5, IL-13 and also leads to severe pathological changes in mucosal organs.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-227)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-227
Lokale Artikelnummer::
PRSI92-227
Beschreibung:
Mouse CCL9 is a small cytokine belonging to the CC chemokine family. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. CCL9 can activate osteoclasts through its receptor CCR1 (the most abundant chemokine receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4329P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4329P
Lokale Artikelnummer::
PRSI4329P
Beschreibung:
BRCC45 peptide is used for blocking the activity of BRCC45 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5929P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5929P
Lokale Artikelnummer::
PRSI5929P
Beschreibung:
ApoA4 peptide is used for blocking the activity of ApoA4 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-114)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-114
Lokale Artikelnummer::
PRSI92-114
Beschreibung:
Insulin-Like Growth Factor II (IGF2) belongs to the insulin family of polypeptide growth factors that is involved in development and growth. Members of this family are structurally homologous to proinsulin, and share higher sequence identity. IGF2 is expressed only from the paternally inherited allele and believed to be secreted by the liver and to circulate in the blood. IGF2 possess growth-promoting activity and can stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF2 is influenced by placental lactogen and may play a role in fetal development.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4787P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4787P
Lokale Artikelnummer::
PRSI4787P
Beschreibung:
Aldh3A1 peptide is used for blocking the activity of Aldh3A1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-311)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-311
Lokale Artikelnummer::
PRSI96-311
Beschreibung:
Alpha-2-HS-glycoprotein (AHSG) is also known as Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A (FETUA), is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the cystatin family of proteases inhibitors and the fetuin class of plasma binding proteins. AHSG / Fetuin A is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. Fetuins are carrier proteins like albumin. Fetuin-A / AHSG forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Thus AHSG / Fetuin A is a potent inhibitor of pathological calcification. Fetuin A / FETUA promotes phagocytosis of apoptotic cells and plays a role in bone development, calcium homeostasis and insulin sensitivity. Mice deficient in Fetuin-A show systemic calcification of soft tissues.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI3363P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3363P
Lokale Artikelnummer::
PRSI3363P
Beschreibung:
ST2 peptide is used for blocking the activity of the ST2 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI6843P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6843P
Lokale Artikelnummer::
PRSI6843P
Beschreibung:
THBS4 peptide is used for blocking the activity of THBS4 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-053)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-053
Lokale Artikelnummer::
PRSI90-053
Beschreibung:
Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-320)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-320
Lokale Artikelnummer::
PRSI91-320
Beschreibung:
IGFBP-4, whose full name is insulin-like growth factor-binding protein 4, is induced by forskolin and N6, O2’dibutyryl sdenosine 3’, or 5’-cyclic monophosphate. It contains IGFBP N-terminal domain and thyroglobulin type-1 domain, and can bind IGF2. The IGF-binding proteins can prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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