[4-(2-Fluorophenoxy)phenyl]methanol
Artikel-Nr:
(BOSSBS-12373R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12373R
Lokale Artikelnummer::
BOSSBS-12373R
Beschreibung:
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. STK33 (serine/threonine kinase 33) is a 514 amino acid protein that belongs to the CaMK (calcium/calmodulin dependent kinase) subfamily of structurally related serine/threonine kinases. Widely expressed at low levels with predominant expression in testis, lung, retina and fetal organs such as brain, heart and spinal cord, STK33 contains one protein kinase domain and functions as a Ser/Thr protein kinase with a possible role in spermatogenesis. The gene encoding STK33 lies within a region on chromosome 11 that has been associated with a variety of defects, including Long QT syndrome, T-cell leukemia, Beckwith-Wiedemann syndrome, Usher syndrome 1C and various other malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(COBBFM-2494-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
FM-2494-1G
Lokale Artikelnummer::
COBBFM-2494-1G
Beschreibung:
7-Methoxy-2-indolboronsäurepinakolester
VE:
1 * 1 g
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Artikel-Nr:
(PRSI4271P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4271P
Lokale Artikelnummer::
PRSI4271P
Beschreibung:
IL-33 peptide is used for blocking the activity of IL-33 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(1003010.)
Lieferant:
USP
Hersteller-Artikelnummer::
1003010
Lokale Artikelnummer::
USPH1003010
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 15 mg
Lieferant:
COMBI-BLOCKS
Beschreibung:
5-Fluor-2-methoxy-4-pyridinboronsäure
Lieferant:
CHEMPUR
Beschreibung:
7-Methoxy-2H-chromen-3-carbonsäureethylester
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 33-55 kDa, identified as CD53 (Workshop VI; Code N-L033). It is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells. CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells. CD53 is a type III membrane with both termini in the cytoplasm and two loops in the extracellular environment. This molecule, in common with other members of tetraspan family, is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. CD53 crosslinking induces calcium flux on human monocyte and B cells. Cross-linking of CD53 promotes activation of resting human B-lymphocytes. This MAb recognizes CD53 transfected cells and partially inhibits T-cell proliferation induced by CD3 antibody (clone: UCHT1).
Artikel-Nr:
(BNUM0324-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0324-50
Lokale Artikelnummer::
BTIUBNUM0324-50
Beschreibung:
Recognizes a protein of 33-55 kDa, identified as CD53 (Workshop VI; Code N-L033). It is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells. CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells. CD53 is a type III membrane with both termini in the cytoplasm and two loops in the extracellular environment. This molecule, in common with other members of tetraspan family, is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. CD53 crosslinking induces calcium flux on human monocyte and B cells. Cross-linking of CD53 promotes activation of resting human B-lymphocytes. This MAb recognizes CD53 transfected cells and partially inhibits T-cell proliferation induced by CD3 antibody (clone: UCHT1).
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-6023R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6023R-A350
Lokale Artikelnummer::
BOSSBS-6023R-A350
Beschreibung:
Bone marrow stromal cell antigen 1 (BST1) is a pleiotropic ectoenzyme which belongs to the CD38 family and to the growing number of leukocyte surface molecules known to act independently as both receptors and enzymes. The BST1 molecule displays two distinct domains in its extracellular component. The first is implicated in the enzymic activities of the molecule (it synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores) and the second domain has adhesion/signalling properties.Bone marrow stromal cell antigen 1 facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
VE:
1 * 100 µl
Lieferant:
CHEMPUR
Beschreibung:
1-Boc-5-methoxy-2-indolboronsäure
Lieferant:
Sigma-Aldrich
Beschreibung:
Ethylenoxid (Oxiran)-Lösung 2.5-3.3 M in THF
Artikel-Nr:
(1.24541.0001)
Lieferant:
Merck
Hersteller-Artikelnummer::
1.24541.0001
Lokale Artikelnummer::
MERC1.24541.0001
Beschreibung:
ß-Nicotinamide adenine dinucleotide phosphate (NADP-Na<sub>2</sub>, oxidized form)
VE:
1 * 1 g
Lieferant:
COMBI-BLOCKS
Beschreibung:
4,5-Dibrom-2-methoxy-N-methylanilin
Artikel-Nr:
(COBBFM-2499-250M)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
FM-2499-250M
Lokale Artikelnummer::
COBBFM-2499-250M
Beschreibung:
5-Methoxy-2-indolboronsäurepinakolester
VE:
1 * 250 mg
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Lieferant:
Sigma-Aldrich
Beschreibung:
2-Methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolan, Sigma-Aldrich®
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelial cells. IL-33 signals through the interleukin 1 receptor-like 1 (IL-1R1) and interleukin-1 receptor accessory protein (IL1RAP) receptors to ativate NF-κB and MAPK signaling pathways. IL-33 functions to induce type 2 cytokine production in polarized Type 2 helper T (Th2) cells.
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