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5-Brom-2-methoxyphenylborons\\u00E4ure
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5-Brom-2-methoxyphenylborons\\u00E4ure
Lieferant:
COMBI-BLOCKS
Beschreibung:
Methyl-5-brom-3-methylpicolinat
Lieferant:
COMBI-BLOCKS
Beschreibung:
1-Methyl-3-(trifluormethyl)-1H-pyrazol-5-boronsäure
Lieferant:
COMBI-BLOCKS
Beschreibung:
Methyl-4-brom-2-methoxybenzoat
Lieferant:
COMBI-BLOCKS
Beschreibung:
Methyl-3-methoxy-4-nitrobenzoat
Lieferant:
FLUOROCHEM
Beschreibung:
Methyl-2,3-dimethoxybenzoat
Artikel-Nr:
(REST31645)
Lieferant:
Restek
Hersteller-Artikelnummer::
31645
Lokale Artikelnummer::
REST31645
Beschreibung:
The mix consists of methyl bromochloroacetate, methyl dibromoacetate, methyl dichloroacetate, methyl monobromoacetate, methyl monochloroacetate, methyl trichloroacetate.
VE:
1 * 1 mL
Artikel-Nr:
(COBBPN-5223-100M)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
PN-5223-100M
Lokale Artikelnummer::
COBBPN-5223-100M
Beschreibung:
5-Chlor-2-methyl-4-(trifluormethyl)phenylboronsäurepinakolester
VE:
1 * 100 mg
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-3381R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3381R-A647
Lokale Artikelnummer::
BOSSBS-3381R-A647
Beschreibung:
mTOR controls cell growth, in part by regulating p70 S6 kinase alpha (p70alpha) and eukaryotic initiation factor 4E binding protein 1 (4EBP1). Raptor is a 150 kDa mTOR binding protein that also binds 4EBP1 and p70alpha. The binding of Raptor to mTOR is necessary for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro, and it strongly enhances the mTOR kinase activity toward p70alpha. Rapamycin or amino acid withdrawal increases, whereas insulin strongly inhibits, the recovery of 4EBP1 and raptor on 7-methyl-GTP Sepharose. Partial inhibition of raptor expression by RNA interference (RNAi) reduces mTOR-catalyzed 4EBP1 phosphorylation in vitro. RNAi of C. elegans raptor yields an array of phenotypes that closely resemble those produced by inactivation of Ce-TOR. Thus, raptor is an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15076R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15076R-A488
Lokale Artikelnummer::
BOSSBS-15076R-A488
Beschreibung:
C1orf77, also known as Friend of PRMT1 protein, is a 248 amino acid protein that plays an essential role in the ligand-dependent activation of estrogen receptor target genes. C1orf77 is tightly associated with chromatin and is modified by both asymmetric and symmetric arginine methylation. Depletion of C1orf77 results in almost complete block of estradiol-induced promter occupancy by the estrogen receptor. Also, complete knockdown of C1orf77 mRNA in adult erythroid progenitors stongly induces fetal hemoglobin, suggesting that C1orf77 is a critical modulator of _-globin gene expression. There are two isoforms of C1orf77 that are produced as a result of alternative splicing events. The gene encoding C1orf77 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
VE:
1 * 100 µl
Artikel-Nr:
(REST32050)
Lieferant:
Restek
Hersteller-Artikelnummer::
32050
Lokale Artikelnummer::
REST32050
Beschreibung:
Organic Standard, 2,4-dichlorophenyl acetic acid methyl ester (DCAA methyl ester), 1 ml/ampoule
VE:
1 * 1 mL
Lieferant:
COMBI-BLOCKS
Beschreibung:
Methyl-4-chlor-2-nitrobenzoat
Lieferant:
Thermo Scientific
Beschreibung:
Methyl-2-isothiocyanatobenzoat
Artikel-Nr:
(BOSSBS-3381R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3381R-A350
Lokale Artikelnummer::
BOSSBS-3381R-A350
Beschreibung:
mTOR controls cell growth, in part by regulating p70 S6 kinase alpha (p70alpha) and eukaryotic initiation factor 4E binding protein 1 (4EBP1). Raptor is a 150 kDa mTOR binding protein that also binds 4EBP1 and p70alpha. The binding of Raptor to mTOR is necessary for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro, and it strongly enhances the mTOR kinase activity toward p70alpha. Rapamycin or amino acid withdrawal increases, whereas insulin strongly inhibits, the recovery of 4EBP1 and raptor on 7-methyl-GTP Sepharose. Partial inhibition of raptor expression by RNA interference (RNAi) reduces mTOR-catalyzed 4EBP1 phosphorylation in vitro. RNAi of C. elegans raptor yields an array of phenotypes that closely resemble those produced by inactivation of Ce-TOR. Thus, raptor is an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3559R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3559R-CY3
Lokale Artikelnummer::
BOSSBS-3559R-CY3
Beschreibung:
mTOR controls cell growth, in part by regulating p70 S6 kinase alpha (p70alpha) and eukaryotic initiation factor 4E binding protein 1 (4EBP1). Raptor is a 150 kDa mTOR binding protein that also binds 4EBP1 and p70alpha. The binding of Raptor to mTOR is necessary for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro, and it strongly enhances the mTOR kinase activity toward p70alpha. Rapamycin or amino acid withdrawal increases, whereas insulin strongly inhibits, the recovery of 4EBP1 and raptor on 7-methyl-GTP Sepharose. Partial inhibition of raptor expression by RNA interference (RNAi) reduces mTOR-catalyzed 4EBP1 phosphorylation in vitro. RNAi of C. elegans raptor yields an array of phenotypes that closely resemble those produced by inactivation of Ce-TOR. Thus, raptor is an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3381R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3381R-A555
Lokale Artikelnummer::
BOSSBS-3381R-A555
Beschreibung:
mTOR controls cell growth, in part by regulating p70 S6 kinase alpha (p70alpha) and eukaryotic initiation factor 4E binding protein 1 (4EBP1). Raptor is a 150 kDa mTOR binding protein that also binds 4EBP1 and p70alpha. The binding of Raptor to mTOR is necessary for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro, and it strongly enhances the mTOR kinase activity toward p70alpha. Rapamycin or amino acid withdrawal increases, whereas insulin strongly inhibits, the recovery of 4EBP1 and raptor on 7-methyl-GTP Sepharose. Partial inhibition of raptor expression by RNA interference (RNAi) reduces mTOR-catalyzed 4EBP1 phosphorylation in vitro. RNAi of C. elegans raptor yields an array of phenotypes that closely resemble those produced by inactivation of Ce-TOR. Thus, raptor is an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3559R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3559R-CY5
Lokale Artikelnummer::
BOSSBS-3559R-CY5
Beschreibung:
mTOR controls cell growth, in part by regulating p70 S6 kinase alpha (p70alpha) and eukaryotic initiation factor 4E binding protein 1 (4EBP1). Raptor is a 150 kDa mTOR binding protein that also binds 4EBP1 and p70alpha. The binding of Raptor to mTOR is necessary for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro, and it strongly enhances the mTOR kinase activity toward p70alpha. Rapamycin or amino acid withdrawal increases, whereas insulin strongly inhibits, the recovery of 4EBP1 and raptor on 7-methyl-GTP Sepharose. Partial inhibition of raptor expression by RNA interference (RNAi) reduces mTOR-catalyzed 4EBP1 phosphorylation in vitro. RNAi of C. elegans raptor yields an array of phenotypes that closely resemble those produced by inactivation of Ce-TOR. Thus, raptor is an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
VE:
1 * 100 µl
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noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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