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1-(2-Hydroxyethyl)imidazole
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1-(2-Hydroxyethyl)imidazole
Artikel-Nr:
(PRSI27-085)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-085
Lokale Artikelnummer::
PRSI27-085
Beschreibung:
PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI49-282)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
49-282
Lokale Artikelnummer::
PRSI49-282
Beschreibung:
Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the eta-amino groups of lysines located near the amino termini of core histone proteins. Eight members of HDAC family have been identified in the past several years. These HDAC family members are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8, each of which contains a deacetylase domain exhibiting from 45 to 93% identity in amino acid sequence. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about twofold larger than those of the class I members, and the deacetylase domains are present within the C-terminal regions, except that HDAC-6 contains two copies of the domain, one within each of the N-terminal and C-terminal regions. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns. These results suggested that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI76-001)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-001
Lokale Artikelnummer::
PRSI76-001
Beschreibung:
The 20RNTC monoclonal antibody specifically reacts with human and mouse interleukin-20 receptor 2 (IL-20R2 or IL-20Rb). IL-20R2 is a class II cytokine receptor that pairs with IL-20R to form a receptor capable of binding IL-19, IL-20, or IL-24 and binds IL-20, or IL-24 when paired with IL-22R1. It is primarily found on epithelial originated cells such as those found in the skin or intestines.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI76-938)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-938
Lokale Artikelnummer::
PRSI76-938
Beschreibung:
The NOK-1 monoclonal antibody specifically reacts with human CD178, which is the CD95 or Fas ligand. CD178 is a TNF superfamily type II transmembrane glycoprotein expressed by activated T and NK cells and is involved in Fas-mediated apoptosis of lymphocytes. CD178 is also expressed by monocytes, neutrophils, granulocytes and the parenchymal cells of the retina and cornea. The NOK-1 antibody has been reported to bind to COOH-terminus of the Fas ligand in the region associated with Fas binding.
VE:
1 * 0,025 mg
New Product
Lieferant:
Cayman Chemical
Beschreibung:
Doxorubicin is an anthracycline anti-tumour antibiotic which involves in inhibition of DNA topoisomerase II by inducing double-stranded DNA breaks. It is also involved in the inhibition of nucleic acid synthesis by intercalating within DNA. The accumulation of the p53 tumour suppressor protein leads to the apoptosis in cells.
Artikel-Nr:
(PRSI92-040)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-040
Lokale Artikelnummer::
PRSI92-040
Beschreibung:
Serine/Threonine-Protein Phosphatase PP1-Υ Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1CC colocalizes with SPZ1 in the nucleus, with URI1 at mitochondrion, Rapidly exchanges between the nucleolar, nucleoplasmic and cytoplasmic compartments. As a cofactor, PPP1CC binds one iron ion and one manganese ion per subunit.. In addition, PPP1CC may play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI77-058)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-058
Lokale Artikelnummer::
PRSI77-058
Beschreibung:
The 11B11 monoclonal antibody specifically reacts with mouse 14 kDa cytokine IL-4, expressed by the activated NKT cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen.The 11B11 antibody neutralizes the IL-4 cytokine.
VE:
1 * 0,5 mg
New Product
Artikel-Nr:
(PRSI77-063)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
77-063
Lokale Artikelnummer::
PRSI77-063
Beschreibung:
The 11B11 monoclonal antibody specifically reacts with mouse 14 kDa cytokine IL-4, expressed by the activated NKT cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen.The 11B11 antibody neutralizes the IL-4 cytokine.
VE:
1 * 0,1 mg
New Product
Lieferant:
Sigma-Aldrich
Beschreibung:
Bariumtitanat, Sigma-Aldrich®
Artikel-Nr:
(PRSI6177)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6177
Lokale Artikelnummer::
PRSI6177
Beschreibung:
OGFOD1 Antibody: OGFOD1, a member of the 2-OG-Fe(II) dioxygenase family, plays an important role in ischemic survival and stress. It is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. An OGFOD1 iron binding residue is required for ATPAF1 gene expression. As a novel stress granule component, OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-457)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-457
Lokale Artikelnummer::
PRSI26-457
Beschreibung:
UGT2A3 is a single-pass type I membrane proteinPotential. It belongs to the UDP-glycosyltransferase family. UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI27-291)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-291
Lokale Artikelnummer::
PRSI27-291
Beschreibung:
ELL was shown to encode a previously uncharacterized elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by polymerase at multiple sites along the DNA. Functionally, ELL resembles Elongin (SIII), a transcription elongation factor regulated by the product of the von Hippel-Lindau (VHL) tumor suppressor gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI7513)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7513
Lokale Artikelnummer::
PRSI7513
Beschreibung:
AIMP1 (Endothelial monocyte-activating polypeptide II, EMAP2) is a proinflammatory cytokine for monocytes and granulocytes. It is specifically induced by apoptosis and is involved in the control of angiogenesis, inflammation, and wound healing (1,2). AIMP1 was identified as one of three auxiliary factors of the mammalian aminoacyl tRNA synthetase (ARS) complex. It binds and facilitates the catalytic reaction of arginyl-tRNA synthetase. Recent studies show that CD23 plays an essential role in the AIMP1-induced immune response and might be a target in the treatment of inflammatory diseases.
VE:
1 * 100 µG
Lieferant:
Thermo Scientific
Beschreibung:
Magnesiumsulfat, wasserfrei 97%, rein
Lieferant:
MP Biomedicals
Beschreibung:
Eosin Y disodium salt is used in combination with Azure II to show morphological details of marrow cells; buffered Azure A/Eosin Y method for demostrating cell granules, microorganisms and nuclei; for showing insect musculature; for demonstrating cells infected with mosquito-iridescent virus; use in combination with Alum Hematoxylin/Azure II to show mast cells, early necrobiotic changes in cells and protozoans, rickettsias and bacteria in tissues; to demonstrate volutin granules in any microorganism; Bond's modification of Mann's Eosin-Methyl Blue for Negri bodies in smears; Harris stain for Negri bodies in smears; Mann's method for staining Negri bodies in sections; Gridley's stain for Endamoeba in tissue sections; a modified methenamine-silver nitrate method for the demonstration of Endamoeba in sections. It is used as a counterstain for hematoxylin.
Artikel-Nr:
(PRSI27-626)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-626
Lokale Artikelnummer::
PRSI27-626
Beschreibung:
POU domain genes encode a family of highly conserved transacting factors that influence the transcriptional activity of several cell type-specific and ubiquitous genes. Studies have cloned and sequenced cDNAs encoding a novel mouse POU domain protein, Oct-11, that is closely related within the POU domain to the POU class II proteins, Oct-1 and Oct-2.
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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