1,1-Bis(hydroxymethyl)cyclopentane
Artikel-Nr:
(SIAL531634-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
531634-1G
Lokale Artikelnummer::
SIAL531634-1G
Beschreibung:
Bis(pyridin)iodoniumtetrafluoroborat, Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(9043-02)
Lieferant:
Avantor
Lokale Artikelnummer::
BAKR9043-02
Beschreibung:
tert-Butylmethylether ≥99,0%, ULTRA RESI-ANALYZED® für die Analyse von organischen Rückständen, J.T.Baker®
VE:
1 * 1 L
Artikel-Nr:
(MIEL11055970)
Lieferant:
MIELE
Hersteller-Artikelnummer::
11055970
Lokale Artikelnummer::
MIEL11055970
Beschreibung:
Zubehör für Glasspülautomaten, A 313 Modul, zur Aufbereitung von großvolumigen Laborkolben bis zu 10 L, runde Kolben bis zu 6 L, Erlenmeyerkolben bis zu 5 L, mit 5 Positionen für Injektordüsen, B×T×H: 200×320×20 mm
VE:
1 * 1 ST
Lieferant:
FLUOROCHEM
Beschreibung:
2,4-Bis(trifluormethyl)phenylacetonitril
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Artikel-Nr:
(BOSSBS-1256R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1256R-HRP
Lokale Artikelnummer::
BOSSBS-1256R-HRP
Beschreibung:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2805R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2805R-HRP
Lokale Artikelnummer::
BOSSBS-2805R-HRP
Beschreibung:
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(SIAL556130-250G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
556130-250G
Lokale Artikelnummer::
SIAL556130-250G
Beschreibung:
Bismut, Sigma-Aldrich®
VE:
1 * 250 g
Artikel-Nr:
(SIAL452386-50G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
452386-50G
Lokale Artikelnummer::
SIAL452386-50G
Beschreibung:
Bismut, Sigma-Aldrich®
VE:
1 * 50 g
Artikel-Nr:
(BOSSBS-11390R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11390R-CY5
Lokale Artikelnummer::
BOSSBS-11390R-CY5
Beschreibung:
AASDHPPT (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase), also known as LYS2, LYS5 or CGI-80, is a 309 amino acid protein that localizes to the cytoplasm and belongs to the P-Pant transferase superfamily. Expressed in testis, liver, kidney, heart, brain, placenta and skeletal muscle, AASDHPPT exists as a monomer that functions to catalyze the phosphopantetheine-dependent post-translational modification of target proteins, effectively transferring a 4'-phosphopantetheine moiety from coenzyme A (CoA) to a serine residue of an acceptor protein. AASDHPPT is subject to DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding AASDHPPT maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11544R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11544R-CY3
Lokale Artikelnummer::
BOSSBS-11544R-CY3
Beschreibung:
Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11690R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11690R-CY5
Lokale Artikelnummer::
BOSSBS-11690R-CY5
Beschreibung:
FIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking. Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), both of which negatively affect the nervous system. CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration. Unlike CMT4J, ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, causing paralysis and, ultimately, death.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Appearance: White to light yellow Crystalline powder
Artikel-Nr:
(APOSOR1755-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR1755-25G
Lokale Artikelnummer::
APOSOR1755-25G
Beschreibung:
tert-Butyl-4-(2-aminoethyl)piperazine-1-carboxylate
VE:
1 * 25 g
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Reagent for aluminium. Aurintricarboxylic acid readily polymerises in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types. Its neuroprotective effect, perhaps due to its ability to prevent down-regulation of Ca²⁺ impermeable GluR2 receptors or to its ability to inhibit calpain, a Ca²⁺-activated protease that is activated during apoptosis.
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