2,8-Dimethylchinolin-4(1H)-on
Artikel-Nr:
(ENAMEN300-59603.1G)
Lieferant:
SIA ENAMINE
Hersteller-Artikelnummer::
EN300-59603.1G
Lokale Artikelnummer::
ENAMEN300-59603.1G
Beschreibung:
2-Amino-5-fluoro-3-methylbenzoic acid
VE:
1 * 1 g
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Artikel-Nr:
(BOSSBS-12877R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12877R-A647
Lokale Artikelnummer::
BOSSBS-12877R-A647
Beschreibung:
Predominantly localized to the nucleolus, BOP1 (Block of proliferation 1 protein) is a 746 amino acid highly conserved non-ribosomal protein that is involved in ribosome biogenesis. Truncation of the amino terminus of BOP1 leads to cell growth arrest in the G1 phase and specific inhibition of 28S and 5.8S rRNA synthesis, as well as a deficit in the cytosolic 60S ribosomal subunit. This suggests that BOP1 is involved in the formation of mature rRNAs and in the biogenesis of the 60S ribosomal subunit. BOP1 physically interacts with pescadillo (a protein involved in cell proliferation) and enables efficient incorporation of pescadillo into the nucleolar preribosomal complexes, thereby affecting rRNA maturation and the cell cycle. The BOP1-pescadillo complex is also necessary for biogenesis of 60S ribosomal subunits. Deregulation of BOP1 may lead to colorectal tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12388R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12388R-A555
Lokale Artikelnummer::
BOSSBS-12388R-A555
Beschreibung:
KIF7 is a 1,343 amino acid protein expressed in embryonic stem cells, melanotic melanoma and Jurkat T-cells. KIF7 is a member of the KIF27 subfamily of the kinesin-like protein family and contains one kinesin-motor domain. It is suggested that KIF7 may participate in the Hedgehog (Hh) signaling pathway by regulating the proteolysis and stability of GLI transcription factors. Hedgehog (Hh) signaling plays a critical role in embryonic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1163R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1163R-A488
Lokale Artikelnummer::
BOSSBS-1163R-A488
Beschreibung:
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. The mature form of Beta defensin 1 is 36 amino acids.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12340R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12340R-A488
Lokale Artikelnummer::
BOSSBS-12340R-A488
Beschreibung:
Vanin-2 is a 520 amino acid GPI-anchor protein that belongs to the CN hydrolase family and BTD/VNN subfamily.Widely expressed with high expression in spleen and blood, vanin-2 is suggested to be involved in thymus homing of bone marrow cells, regulation of Integrin ∫2-mediated cell adhesion, and migration and motility of neutrophils. Vanin-2 exists as five alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 6q23.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5467R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5467R-A750
Lokale Artikelnummer::
BOSSBS-5467R-A750
Beschreibung:
Gamma Catenin is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of gamma Catenin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. It is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5467R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5467R-FITC
Lokale Artikelnummer::
BOSSBS-5467R-FITC
Beschreibung:
Gamma Catenin is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of gamma Catenin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. It is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12191R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12191R-A647
Lokale Artikelnummer::
BOSSBS-12191R-A647
Beschreibung:
DZIP3 is a 1,208 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger. Expressed in a variety of tissues with highest expression in heart, skeletal muscle and kidney, DZIP3 functions as an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme, thereby playing a role in signaling events throughout the cell. Multiple isoforms of DZIP3 exist due to alternative splicing events.
VE:
1 * 100 µl
Lieferant:
FLUOROCHEM
Beschreibung:
3-Amino-5-nitrobenzoesäure
Artikel-Nr:
(BOSSBS-8874R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8874R-A680
Lokale Artikelnummer::
BOSSBS-8874R-A680
Beschreibung:
The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalisation, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4106R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4106R-CY5.5
Lokale Artikelnummer::
BOSSBS-4106R-CY5.5
Beschreibung:
FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8360R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8360R-A680
Lokale Artikelnummer::
BOSSBS-8360R-A680
Beschreibung:
The leucine-rich repeat-containing protein 2 (LRRC2) is a 371 amino acid protein that contains 9 LRR repeats. The gene encoding LRRC2 maps to chromosome 3, which encodes over 1,100 genes. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8577R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8577R-CY3
Lokale Artikelnummer::
BOSSBS-8577R-CY3
Beschreibung:
GPKOW is a potential RNA-binding protein consisting of one central G patch domain and two C-terminal KOW domains. T54 is a 476 amino acid protein belonging to the MOS2 family. It is a mammalian homolog of the Arabidopsis thaliana MOS2 (modifier of SNC1, 2) nuclear protein that is required for innate immunity. Similar to A. thaliana MOS2, T54 localizes to the nucleus and contains G patch and KOW domains, suggesting that T54 may play a similar role in mammalian innate immunity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8360R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8360R-CY7
Lokale Artikelnummer::
BOSSBS-8360R-CY7
Beschreibung:
The leucine-rich repeat-containing protein 2 (LRRC2) is a 371 amino acid protein that contains 9 LRR repeats. The gene encoding LRRC2 maps to chromosome 3, which encodes over 1,100 genes. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10400R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10400R-A680
Lokale Artikelnummer::
BOSSBS-10400R-A680
Beschreibung:
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt Signalling are likely to be conserved among metazoans.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4106R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4106R
Lokale Artikelnummer::
BOSSBS-4106R
Beschreibung:
FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified.
VE:
1 * 100 µl
Preis auf Anfrage
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