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3-Chlor-5-propoxyphenylborons\\u00E4urepinakolester
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3-Chlor-5-propoxyphenylborons\\u00E4urepinakolester
Lieferant:
MP Biomedicals
Beschreibung:
1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.
Lieferant:
Thermo Fisher Scientific
Beschreibung:
Use Thermo Scientific™ SureSTART™ 9 mm screw caps with screw vials that have a 9 mm opening, including our SureSTART 2 ml glass screw vials and 1,7 ml glass high recovery screw microvials for <2 ml samples (level 2). Select level 2 products for high-throughput applications, when robustness and reproducibility are key.
Artikel-Nr:
(PRSI26-828)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-828
Lokale Artikelnummer::
PRSI26-828
Beschreibung:
The exact function of C17orf39 remains unknown.The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith-Magenis syndrome region on chromosome 17.
VE:
1 * 50 µG
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Brom-N-methyl-2-(trifluormethyl)anilin Hydrochlorid
Artikel-Nr:
(BOSSBS-1380R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1380R-A750
Lokale Artikelnummer::
BOSSBS-1380R-A750
Beschreibung:
G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilisation and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine, reproductive, immune and central nervous systems. Has a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a RAMP3-dependent manner. Regulates arterial blood pressure by stimulating vasodilation and reducing vascular smooth muscle and microvascular endothelial cell proliferation. Plays a role in blood glucose homeostasis contributing to the insulin secretion response by pancreatic beta cells. Triggers mitochondrial apoptosis during pachytene spermatocyte differentiation. Stimulates uterine epithelial cell proliferation. Enhances uterine contractility in response to oxytocin. Contributes to thymic atrophy by inducing apoptosis. Attenuates TNF-mediated endothelial expression of leukocyte adhesion molecules. Promotes neuritogenesis in developing hippocampal neurons. Plays a role in acute neuroprotection against NMDA-induced excitotoxic neuronal death. Increases firing activity and intracellular calcium oscillations in luteinizing hormone-releasing hormone (LHRH) neurons. Inhibits early osteoblast proliferation at growth plate during skeletal development. Inhibits mature adipocyte differentiation and lipid accumulation. Involved in the recruitment of beta-arrestin 2 ARRB2 at the plasma membrane in epithelial cells.
VE:
1 * 100 µl
Lieferant:
Spectrum Chemical
Beschreibung:
Thiamine Hydrochloride, FCC is the hydrochloride salt of vitamin B1 and used to treat or prevent vitamin B1 deficiency. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Lieferant:
Sigma-Aldrich
Beschreibung:
Glycinmethylester Hydrochlorid (H-Gly-OMe.HCl), Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
Cäsiumchlorid 99.99% Trace metals basis, Optical Grade Spectroscopy
Artikel-Nr:
(SIAL73200-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
73200-1G
Lokale Artikelnummer::
SIAL73200-1G
Beschreibung:
O-(4-Nitrobenzyl)hydroxylamin Hydrochlorid, Sigma-Aldrich®
VE:
1 * 1 g
Lieferant:
BACHEM BIOCHEMICA
Beschreibung:
Glycinmethylester Hydrochlorid (H-Gly-OMe.HCl)
Lieferant:
COMBI-BLOCKS
Beschreibung:
4,5,6,7-Tetrahydro-1H-indazol Hydrochlorid
Lieferant:
COMBI-BLOCKS
Beschreibung:
6-Brom-7-methylimidazo[1,2-a]pyridin Hydrochlorid
Artikel-Nr:
(COBBHC-3349-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
HC-3349-1G
Lokale Artikelnummer::
COBBHC-3349-1G
Beschreibung:
4-(1,3-Oxazol-2-yl)anilin Hydrochlorid
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-((Trifluormethyl)thio)benzoesäure
Artikel-Nr:
(BOSSBS-2734R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2734R-CY5
Lokale Artikelnummer::
BOSSBS-2734R-CY5
Beschreibung:
Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. Forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Represses its target genes by binding directly to the DNA sequence 5'-TTCCTAGAA-3' (BCL6-binding site) or indirectly by repressing the transcriptional activity of transcription factors. In GC B-cells, represses genes that function in differentiation, inflammation, apoptosis and cell cycle control, also autoregulates its transcriptional expression and up-regulates, indirectly, the expression of some genes important for GC reactions, such as AICDA, through the repression of microRNAs expression, like miR155. An important function is to allow GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. In follicular helper CD4(+) T-cells (T(FH) cells), promotes the expression of T(FH)-related genes but inhibits the differentiation of T(H)1, T(H)2 and T(H)17 cells. Also required for the establishment and maintenance of immunological memory for both T- and B-cells. Suppresses macrophage proliferation through competition with STAT5 for STAT-binding motifs binding on certain target genes, such as CCL2 and CCND2. In response to genotoxic stress, controls cell cycle arrest in GC B-cells in both p53/TP53-dependedent and -independent manners. Besides, also controls neurogenesis through the alteration of the composition of NOTCH-dependent transcriptional complexes at selective NOTCH targets, such as HES5, including the recruitment of the deacetylase SIRT1 and resulting in an epigenetic silencing leading to neuronal differentiation.
VE:
1 * 100 µl
Preis auf Anfrage
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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