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45 019 results were found
Natriummetavanadat
Artikel-Nr:
(BOSSBS-12330R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12330R-A680
Lokale Artikelnummer::
BOSSBS-12330R-A680
Beschreibung:
The tripartite motif (TRIM) family of proteins are characterised by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. Staf-50 (50 kDa-stimulated trans-acting factor), also known as TRIM22 (tripartite motif-containing 22), RNF94 or GPSTAF50, is a 498 amino acid cytoplasmic protein that belongs to the TRIM family and, characteristic of TRIM family members, contains one RING-type zinc finger, one B box-type zinc finger and one SPRY domain. Induced by IFN-å and IFN-, Staf-50 is strongly expressed in ovary, spleen, thymus and peripheral blood leukocytes where it is thought to mediate the antiviral effects of IFN proteins. Additionally, Staf-50 is present in leukemic cells, suggesting a role in cancer formation and metastasis. Staf-50 exists as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 11.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6592R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6592R-A350
Lokale Artikelnummer::
BOSSBS-6592R-A350
Beschreibung:
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.Tissue specificity; Detected in liver and prostate (at protein level). Detected in adult liver, lung, brain, placenta, prostate, adrenal gland, testis, mammary gland, spleen, spinal cord and uterus. Detected in caudate nucleus, and at lower levels in amygdala, corpus callosum, hippocampus, substantia nigra and thalamus. Detected in fetal lung, liver and brain.Sequence similarities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD31977-100G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD31977-100G
Lokale Artikelnummer::
BLDPBD31977-100G
Beschreibung:
H-D-Glu(OBzl)-OBzl·HCl 97%
VE:
1 * 100 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Amino-1-(2-fluorophenyl)ethanol 97%
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Nigrosin, alcohol soluble. Nigrosin is a black colored powder. It is widely used to manufacture ink and shoe polish. It is also employed for dyeing leather, wood and textiles. In addition, alcohol soluble nigrosin dye is used in carbon papers, typewriter and ribbons. It is used as an ingredient in rubber repairing lacquer.
Artikel-Nr:
(PRSI92-055)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-055
Lokale Artikelnummer::
PRSI92-055
Beschreibung:
Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyses the cis-trans isomerisation of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells.
VE:
1 * 50 µG
Artikel-Nr:
(BLDPBD214199-100MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD214199-100MG
Lokale Artikelnummer::
BLDPBD214199-100MG
Beschreibung:
Morpholine-2-carboxylic acid 96%
VE:
1 * 100 mg
Artikel-Nr:
(BOSSBS-13343R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-A350
Lokale Artikelnummer::
BOSSBS-13343R-A350
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13343R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-CY7
Lokale Artikelnummer::
BOSSBS-13343R-CY7
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7736R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7736R-A488
Lokale Artikelnummer::
BOSSBS-7736R-A488
Beschreibung:
Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9201R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9201R-FITC
Lokale Artikelnummer::
BOSSBS-9201R-FITC
Beschreibung:
IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
H-Gln-OtBu·HCl 98%
Lieferant:
Alfa Aesar
Beschreibung:
1-[(Ammoniooxy)methyl]-4-methoxybenzolchlorid 98%
Artikel-Nr:
(EHERC11667490)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C11667490
Lokale Artikelnummer::
EHERC11667490
Beschreibung:
Benzylcinnamat
VE:
1 * 0,25 g
Lieferant:
Alfa Aesar
Beschreibung:
Malonaldehydebis(phenylimine) monohydrochloride ≥98%
Artikel-Nr:
(ICNA0210293780)
Lieferant:
MP Biomedicals
Hersteller-Artikelnummer::
0210293780
Lokale Artikelnummer::
ICNA0210293780
Beschreibung:
Sorbic acid (2,4-hexadienoic acid) is a straight chain unsaturated fatty acid. It is an antimicrobial agent. The antimicrobial action of sorbic acid is due to its inhibitory influence on various enzymes in the microbial cell such as enzymes involved in carbohydrate metabolism such as enolase and lactate dehydrogenase, enzymes of citric acid cycles.
VE:
1 * 100 g
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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