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2,2-Dimethylbut-3-ynoic+acid
Artikel-Nr:
(BOSSBS-11722R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11722R-A750
Lokale Artikelnummer::
BOSSBS-11722R-A750
Beschreibung:
Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome. DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22. Expressed ubiquitously with highest levels in heart, liver and skeletal muscle, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin 1, both of which are involved in early tissue development. The gene encoding DGCR6, along with other DGCR genes, is deleted in DiGeorge syndrome; a developmental disorder characterised by improper facial, cardiac and palate formation. Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, as well as in Burkitt lymphoma and lymphocytes transformed by EBV. Due to a duplication of the ancestral DGCR6 locus, there are two functional, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11722R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11722R-CY5
Lokale Artikelnummer::
BOSSBS-11722R-CY5
Beschreibung:
Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome. DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22. Expressed ubiquitously with highest levels in heart, liver and skeletal muscle, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin ?1, both of which are involved in early tissue development. The gene encoding DGCR6, along with other DGCR genes, is deleted in DiGeorge syndrome; a developmental disorder characterized by improper facial, cardiac and palate formation. Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, as well as in Burkitt抯 lymphoma and lymphocytes transformed by EBV. Due to a duplication of the ancestral DGCR6 locus, there are two functional, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5827R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5827R-CY5
Lokale Artikelnummer::
BOSSBS-5827R-CY5
Beschreibung:
PCDHGB5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Silber ≥99,999% (Metall-Basis), Schnecke, Premion®, Länge 12.7 mm (0.50 in), Ø 6.35 mm (0.25 in)
Lieferant:
Alfa Aesar
Beschreibung:
Silber ≥99,999% (Metall-Basis), Schnecke, Premion®, Länge 3.175 mm (0.125 in), Ø 3.175 mm (0.125 in)
Artikel-Nr:
(BOSSBS-5827R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5827R-FITC
Lokale Artikelnummer::
BOSSBS-5827R-FITC
Beschreibung:
PCDHGB5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5827R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5827R-A350
Lokale Artikelnummer::
BOSSBS-5827R-A350
Beschreibung:
PCDHGB5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5827R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5827R-A488
Lokale Artikelnummer::
BOSSBS-5827R-A488
Beschreibung:
PCDHGB5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
VE:
1 * 100 µl
Lieferant:
FLUOROCHEM
Beschreibung:
2,2-Dimethylbernsteinsäureanhydrid
Lieferant:
Sigma-Aldrich
Beschreibung:
2,2'-Dipyridyldisulfid, Sigma-Aldrich®
Artikel-Nr:
(CHMPFL13708.POR)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
FL13708.POR
Lokale Artikelnummer::
CHMPFL13708.POR
Beschreibung:
2,2':5',2''-Terthiophen
VE:
1 * 1 ST
Lieferant:
Alfa Aesar
Beschreibung:
Aluminiumtri-sec-butanolat 97%
Artikel-Nr:
(80011-2)
Lieferant:
Biotium
Hersteller-Artikelnummer::
80011-2
Lokale Artikelnummer::
BTIU80011-2
Beschreibung:
Calcein AM is a widely used green fluorescent cell marker. Calcein AM is membrane-permeant and thus can be introduced into cells via incubation.
VE:
1 * 1 mL
Artikel-Nr:
(ACRO156000250)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
156000250
Lokale Artikelnummer::
ACRO156000250
Beschreibung:
Appearance: Light yellow to light brown Crystalline powder
VE:
1 * 25 g
Artikel-Nr:
(FLUO021351-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
021351-1G
Lokale Artikelnummer::
FLUO021351-1G
Beschreibung:
2,2-Diphenylthioacetamid
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-8548R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8548R-A488
Lokale Artikelnummer::
BOSSBS-8548R-A488
Beschreibung:
The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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