Suche >
Imidazo[1,2-b]pyridazin
Drucken
Sie suchten nach:
47 193 results were found
Imidazo[1,2-b]pyridazin
Artikel-Nr:
(APOSOR32162-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR32162-1G
Lokale Artikelnummer::
APOSOR32162-1G
Beschreibung:
5-[4-(1H-Imidazol-1-yl)phenyl]-1H-pyrazole
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1H,1H,2H,2H-Perfluoroctyltrichlorsilan 97%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1H,1H-Heptafluoro-n-butyl methacrylate 97%
Artikel-Nr:
(BOSSBS-2445R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2445R-A488
Lokale Artikelnummer::
BOSSBS-2445R-A488
Beschreibung:
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis (PubMed:22422861, PubMed:24814515). AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity. Other known AURKB substrates involved in centromeric functions and mitosis are CENPA, DES/desmin, GPAF, KIF2C, NSUN2, RACGAP1, SEPT1, VIM/vimentin, GSG2/Haspin, and histone H3. A positive feedback loop involving GSG2 and AURKB contributes to localization of CPC to centromeres. Phosphorylation of VIM controls vimentin filament segregation in cytokinetic process, whereas histone H3 is phosphorylated at 'Ser-10' and 'Ser-28' during mitosis (H3S10ph and H3S28ph, respectively). A positive feedback between GSG2 and AURKB contributes to CPC localization. AURKB is also required for kinetochore localization of BUB1 and SGOL1. Phosphorylation of p53/TP53 negatively regulates its transcriptional activity. Key regulator of active promoters in resting B- and T-lymphocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2445R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2445R-FITC
Lokale Artikelnummer::
BOSSBS-2445R-FITC
Beschreibung:
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis (PubMed:22422861, PubMed:24814515). AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity. Other known AURKB substrates involved in centromeric functions and mitosis are CENPA, DES/desmin, GPAF, KIF2C, NSUN2, RACGAP1, SEPT1, VIM/vimentin, GSG2/Haspin, and histone H3. A positive feedback loop involving GSG2 and AURKB contributes to localization of CPC to centromeres. Phosphorylation of VIM controls vimentin filament segregation in cytokinetic process, whereas histone H3 is phosphorylated at 'Ser-10' and 'Ser-28' during mitosis (H3S10ph and H3S28ph, respectively). A positive feedback between GSG2 and AURKB contributes to CPC localization. AURKB is also required for kinetochore localization of BUB1 and SGOL1. Phosphorylation of p53/TP53 negatively regulates its transcriptional activity. Key regulator of active promoters in resting B- and T-lymphocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2445R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2445R-A647
Lokale Artikelnummer::
BOSSBS-2445R-A647
Beschreibung:
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis (PubMed:22422861, PubMed:24814515). AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity. Other known AURKB substrates involved in centromeric functions and mitosis are CENPA, DES/desmin, GPAF, KIF2C, NSUN2, RACGAP1, SEPT1, VIM/vimentin, GSG2/Haspin, and histone H3. A positive feedback loop involving GSG2 and AURKB contributes to localization of CPC to centromeres. Phosphorylation of VIM controls vimentin filament segregation in cytokinetic process, whereas histone H3 is phosphorylated at 'Ser-10' and 'Ser-28' during mitosis (H3S10ph and H3S28ph, respectively). A positive feedback between GSG2 and AURKB contributes to CPC localization. AURKB is also required for kinetochore localization of BUB1 and SGOL1. Phosphorylation of p53/TP53 negatively regulates its transcriptional activity. Key regulator of active promoters in resting B- and T-lymphocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2445R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2445R-CY5
Lokale Artikelnummer::
BOSSBS-2445R-CY5
Beschreibung:
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis (PubMed:22422861, PubMed:24814515). AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity. Other known AURKB substrates involved in centromeric functions and mitosis are CENPA, DES/desmin, GPAF, KIF2C, NSUN2, RACGAP1, SEPT1, VIM/vimentin, GSG2/Haspin, and histone H3. A positive feedback loop involving GSG2 and AURKB contributes to localization of CPC to centromeres. Phosphorylation of VIM controls vimentin filament segregation in cytokinetic process, whereas histone H3 is phosphorylated at 'Ser-10' and 'Ser-28' during mitosis (H3S10ph and H3S28ph, respectively). A positive feedback between GSG2 and AURKB contributes to CPC localization. AURKB is also required for kinetochore localization of BUB1 and SGOL1. Phosphorylation of p53/TP53 negatively regulates its transcriptional activity. Key regulator of active promoters in resting B- and T-lymphocytes.
VE:
1 * 100 µl
Artikel-Nr:
(REST32566)
Lieferant:
Restek
Hersteller-Artikelnummer::
32566
Lokale Artikelnummer::
REST32566
Beschreibung:
Organonitrogen compounds that has accurately identify and quantify pesticide residues by GC-MS/MS in fruits, vegetables, botanicals, and herbals such as tea, ginseng, ginger, echinacea, and dietary supplements.
VE:
1 * 1 mL
Artikel-Nr:
(APOSPC450365-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC450365-25G
Lokale Artikelnummer::
APOSPC450365-25G
Beschreibung:
Bis(1H,1H-perfluorohexyl) carbonate
VE:
1 * 25 g
Artikel-Nr:
(APOSPC450439-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC450439-25G
Lokale Artikelnummer::
APOSPC450439-25G
Beschreibung:
Isopropyl 1H,1H-perfluorohexyl carbonate
VE:
1 * 25 g
Artikel-Nr:
(APOSOR183434-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR183434-1G
Lokale Artikelnummer::
APOSOR183434-1G
Beschreibung:
3-(1H-Pyrazol-3-yl)-1H-indole
VE:
1 * 1 g
Artikel-Nr:
(APOSPC450413-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC450413-25G
Lokale Artikelnummer::
APOSPC450413-25G
Beschreibung:
Ethyl 1H,1H-perfluorohexyl carbonate
VE:
1 * 25 g
Artikel-Nr:
(APOSPC6173-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC6173-25G
Lokale Artikelnummer::
APOSPC6173-25G
Beschreibung:
1H,1H,2H,2H-Perfluoroctylmethyldichlorsilan 97%
VE:
1 * 25 g
Artikel-Nr:
(PRSI29-293)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-293
Lokale Artikelnummer::
PRSI29-293
Beschreibung:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA1 is a member of the peptidase T1A family which is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
VE:
1 * 50 µG
Artikel-Nr:
(APOSPC450173-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC450173-1G
Lokale Artikelnummer::
APOSPC450173-1G
Beschreibung:
Hexakis(1H,1H-perfluorohexyloxy)phosphazene
VE:
1 * 1 g
Artikel-Nr:
(APOSPC450176-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC450176-1G
Lokale Artikelnummer::
APOSPC450176-1G
Beschreibung:
Hexakis(1H,1H-nonafluoropentoxy)phosphazene 95%
VE:
1 * 1 g
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
