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2-Amino-5-bromo-4-methoxybenzoic+acid
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2-Amino-5-bromo-4-methoxybenzoic+acid
Artikel-Nr:
(BOSSBS-12278R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12278R
Lokale Artikelnummer::
BOSSBS-12278R
Beschreibung:
SOHLH1 is a 328 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one bHLH domain through which it may function as a transcription factor during oogenesis and spermatogenesis. The gene encoding SOHLH1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11940R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11940R-HRP
Lokale Artikelnummer::
BOSSBS-11940R-HRP
Beschreibung:
Retinoic acid induced 1 (RAI1) is a 1,906 amino acid protein containing an N-terminal polyglutamine stretch that is expressed in most tissues, with highest expression in neuronal tissues. RAI1 functions as a transcriptional regulator and is important for embryonic and postnatal developments. Heterozygous deletions of the RAI1 gene are associated with Smith-Magenis syndrome (SMS), a mental retardation syndrome with behavioral, neurological and skeletal anomalies. Individuals affected with SMS usually display self-injurious behaviors, sleep disturbance, developmental delay and reduced motor and cognitive skills. RAI1 haploinsufficiency is specifically responsible for the obesity and craniofacial symptoms of SMS. RAI1 mutations have also been implicated in schizophrenia and spinocerebellar ataxia type 2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7964R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7964R
Lokale Artikelnummer::
BOSSBS-7964R
Beschreibung:
ANKRD9 is a 317 amino acid protein that contains three ANK repeats. Encoded by a gene that maps to human chromosome 14q32.31, ANKRD9 is conserved in chimpanzee, dog, cow, mouse, rat and zebrafish. Hepatic mRNA levels of ANKRD9 are repressed by both thyroid hormone (T(3)) and fasting, and re-elevate by feeding after fasting. ANKRD9 mRNA levels also decrease in response to apoptosis. Localizing to cytoplasm, ANKRD9 may be involved in intracellular lipid accumulation and lipid metabolism. ANKRD9 may also function as a molecular chaperone
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9596R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9596R-A488
Lokale Artikelnummer::
BOSSBS-9596R-A488
Beschreibung:
SPAG17 (sperm associated antigen 17), also known as PF6, is a 2,223 amino acid cytoplamic protein that colocalizes with SPAG6 to microtubles. Highly expressed in testis and in organs that contain cilia-bearing cells including brain, oviduct, lung, and uterus, SPAG17 may be important for the structural integrity of the central apparatus of the sperm axoneme. SPAG17 contains two LRR (leucine-rich) repeats and may also participate in flagellar motility and male fertility.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9596R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9596R-A647
Lokale Artikelnummer::
BOSSBS-9596R-A647
Beschreibung:
SPAG17 (sperm associated antigen 17), also known as PF6, is a 2,223 amino acid cytoplamic protein that colocalizes with SPAG6 to microtubles. Highly expressed in testis and in organs that contain cilia-bearing cells including brain, oviduct, lung, and uterus, SPAG17 may be important for the structural integrity of the central apparatus of the sperm axoneme. SPAG17 contains two LRR (leucine-rich) repeats and may also participate in flagellar motility and male fertility.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11051R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11051R-CY3
Lokale Artikelnummer::
BOSSBS-11051R-CY3
Beschreibung:
HAPLN2 is a 340 amino acid protein encoded by the human gene HAPLN2. HAPLN2 belongs to the HAPLN family and contains one immunoglobulin (Ig)-like, V-type domain and two link domains. HAPLN2 mediates a firm binding of versican V2 to hyaluronic acid. HAPLN2 is believed to play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS), which facilitates neuronal conduction and general structural stabilization. HAPLN2 may also be involved in the formation of extracellular matrices, contributing to perineuronal nets and facilitating the understanding of a functional role of these extracellular matrices. HAPLN2 is found in several nuclei throughout the midbrain and hindbrain in a perineuronal net pattern.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL218766-250G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
218766-250G
Lokale Artikelnummer::
SIAL218766-250G
Beschreibung:
2-Amino-5-methylbenzolsulfonsäure, Sigma-Aldrich®
VE:
1 * 250 g
Artikel-Nr:
(BOSSBS-15420R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15420R
Lokale Artikelnummer::
BOSSBS-15420R
Beschreibung:
HBS1L is a 684 amino acid protein that belongs to the GTP-binding elongation factor family and exists as multiple alternatively spliced isoforms. Expressed in kidney, brain, heart, placenta, liver, muscle and pancreas, HSB1L is thought to play a role in controlling fetal hemoglobin levels, specifically influencing platelet, monocyte and erythrocyte hemoglobin content. The gene encoding HBS1L maps to a locus on human chromosome 6 that is associated with sickle cell anemia and β-thalassemia, suggesting a role for HBS1L in the pathogenesis of blood disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15453R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15453R-A555
Lokale Artikelnummer::
BOSSBS-15453R-A555
Beschreibung:
HEMK2 is a 214 amino acid protein that belongs to the methyltransferase superfamily and exists as multiple alternatively spliced isoforms. The gene encoding HEMK2 maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1,5% of the human genome. Chromosome 21-associated disorders include Alzheimer's disease, amyotrophic lateral sclerosis and, most notably, Down syndrome (also known as trisomy 21).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8339R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8339R-HRP
Lokale Artikelnummer::
BOSSBS-8339R-HRP
Beschreibung:
The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA) biosynthesis. Coenzyme A is an important coenzyme involved in the synthesis and oxidation of fatty acids, as well as the oxidation of pyruvate in the citric acid (Krebs) cycle. Pantothenate kinase 3 (PANK3) is a 370 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK3 is regulated by feedback inhibition by CoA and its thioesters. PANK3 transfers a phosphate from ATP to pantothenate (Vitamin B5), resulting in formation of 4’-phosphopantothenate. Closely related to its family members, PANK1, PANK2 and PANK4, PANK3 is highly expressed in liver. Pantothenate kinase associated neurodegeneration (PKAN) results from mutations in the gene encoding PANK2, the only mitochondria targeted human PANK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12462R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12462R-A750
Lokale Artikelnummer::
BOSSBS-12462R-A750
Beschreibung:
AGPS is a 658 amino acid enzyme that is required for glycerolipid metabolism and ether lipid biosynthesis. localised to the inner aspect of the peroxisomal membrane, AGPS is likely part of a heterotrimeric complex that is also composed of GNPAT and a modified form of GNPAT. Containing one FAD-binding PCMH-type domain, AGPS utilizes FAD as a cofactor in the synthesis of alkyl-glycerone 3-phophate and a long-chain acid anion from 1-acteyl-glyerone 3-phosphate and a long-chain alcohol. Defects in the gene encoding AGPS results in rhizomelic chondrodysplasia punctata type 3, a disease characterised by vertebral disorders, severe mental retardation, cutaneous lesions, cataracts and rhizomelic shortening of the humerus and femur.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0813R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0813R-A750
Lokale Artikelnummer::
BOSSBS-0813R-A750
Beschreibung:
Casein is the name for a family of related phosphoproteins. These proteins are commonly found in mammalian milk, making up 80% of the proteins in cow milk and between 20% and 45% of the proteins in human milk. Casein has a wide variety of uses, from being a major component of cheese, to use as a food additive, to a binder for safety matches. As a food source, casein supplies amino acids; carbohydrates; and two inorganic elements, calcium and phosphorus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9348R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9348R-CY7
Lokale Artikelnummer::
BOSSBS-9348R-CY7
Beschreibung:
ACLP2 (acid phosphatase-like 2), also known as UNQ370 or PRO706, is a 480 amino acid secreted protein that functions to catalyze the H2O-dependent conversion of a phosphate monoester to an alcohol and a phosphate. Expressed as two alternatively spliced isoforms, ACPL2 is encoded by a gene that maps to chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11913R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11913R-CY7
Lokale Artikelnummer::
BOSSBS-11913R-CY7
Beschreibung:
NPDC-1 (Neural Proliferation Differentiation and Control-1) is expressed in neurons once they have stopped dividing and begun to differentiate. NPDC-1 is transported from the Golgi apparatus via vesicles before becoming internalized by endosomes at the cell membrane. NPDC-1 interacts with Cdk2, D-type cyclins, and the transcription factor E2F1. This interaction can lead to an increased replication time, and might have implications in final neural differentiation and apoptosis. NPDC-1 has been shown to colocalize with synaptic vesicle proteins: synaptophysin, synaptobrevin 2, and Rab3 GEP (Rab3 GTP/GDP exchange protein). One function of NPDC-1 is to regulate retinoic acid-mediated events by directly interacting with retinoid receptors. The amino acid sequence of NPDC-1 is highly conserved between mouse, rat, and human.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11323R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11323R-CY3
Lokale Artikelnummer::
BOSSBS-11323R-CY3
Beschreibung:
Neuroglycan C is a brain-specific chondroitin sulfate proteoglycan (CSPG) implicated in the proliferation of neural stem and progenitor cells. Neuro-glycan C is a single-pass membrane protein that can manifest as a part-time proteoglycan depending on the tissue expressing it. In its proteoglycan form, Neuroglycan C exhibits chondroitin sulfate glycans and functions as a receptor for midkine, a growth factor that binds heparin, to affect cytoskeletal changes. By means of ectodomain shedding, the ectodomain of Neuroglycan C is able to enhance neurite outgrowth from neurons. Neurite growth stimulation is affected by both an EGF-like and an acidic amino acid domain found on the shed ectodomain. Both domains instigate neurite growth, however, these domains exhibit differing functionality as to number of neurites produced and neuron types stimulated.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12025R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12025R
Lokale Artikelnummer::
BOSSBS-12025R
Beschreibung:
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR116 (G protein-coupled receptor 116) is a 1,346 amino acid multi-pass membrane protein that contains one SEA domain, one GPS domain and three Ig-like domains and belongs to the GPR family. Existing as a dilsulfide-liked homodimer at the cell surface, GPR116 exists as multiple alternatively spliced isoforms and is thought to play a role in regulating and maintaining proper acid-base balance throughout the cell.
VE:
1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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