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2-Chloro-4-methylnicotinic+acid+ethyl+ester
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2-Chloro-4-methylnicotinic+acid+ethyl+ester
Lieferant:
Tonbo Biosciences
Beschreibung:
The C17.8 antibody is specific for the 40 kDa (p40) protein subunit shared by the cytokines IL-12 and IL-23. To form IL-12, p40 assembles with a separate 35 kDa protein known as p35, resulting in a 70 kDa functional cytokine. IL-12 is secreted by activated monocytes, macrophages, and dendritic cells, and has been shown to target naïve, resting CD4+ T cells to promote their proliferation and secretion of cytokines. IL-23 contains the p40 subunit in combination with a 19 kDa protein chain, p19; its primary source being activated dendritic cells and other antigen-presenting cells. IL-23 appears to target different cell types than IL-12, acting on memory CD4+ T cells to induce a strong proliferative response and contributing to the generation and expansion of Th17 cells. Like the cytokines themselves, the receptors for IL-12 and IL-23 share one subunit, as well as containing distinct cytokine-specific subunits.
Artikel-Nr:
(USBI123359)
Lieferant:
US Biological
Hersteller-Artikelnummer::
123359
Lokale Artikelnummer::
USBI123359
Beschreibung:
Anti-ANXA3 Mouse Monoclonal Antibody [clone: 4F1]
VE:
1 * 100 µG
Artikel-Nr:
(APOSOR5247-100G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR5247-100G
Lokale Artikelnummer::
APOSOR5247-100G
Beschreibung:
N,N-Dimethyl-1,4-phenylendiammoniumdichlorid 95%
VE:
1 * 100 g
Artikel-Nr:
(BOSSBS-9047R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-CY7
Lokale Artikelnummer::
BOSSBS-9047R-CY7
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Lieferant:
Hach
Beschreibung:
Test kit, Chlorine (free) DPD, Messbereich: 0 - 3,5 mg/l
Lieferant:
Alfa Aesar
Beschreibung:
Isradipin ≥98%
Lieferant:
AIR LIQUIDE CRYOTECHNIC
Beschreibung:
Kryogenischer Vorratsbehälter, Rollenuntersatz, nicht magnetisch, Für: Arpege 40/55/75, GT21/26/35/38/40, TP/TR 35/60/100
Artikel-Nr:
(BURK0331-0050)
Lieferant:
BURKLE
Hersteller-Artikelnummer::
0331-0050
Lokale Artikelnummer::
BURK0331-0050
Beschreibung:
HDPE, durchscheinend.
VE:
1 * 1 ST
Lieferant:
DIXON SCIENTIFIC
Beschreibung:
Borosilicate glass
Lieferant:
Sigma-Aldrich
Beschreibung:
Bromphenolblau Natriumsalz, Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
Bromphenolblau Natriumsalz ACS
Lieferant:
Lovibond Tintometer
Beschreibung:
Test kit, VARIO molybdenum HR1 (powder pack), Messbereich: 0 – 35 mg/l Mo, Für Gerät: MD 600
Artikel-Nr:
(BOSSBS-9047R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-HRP
Lokale Artikelnummer::
BOSSBS-9047R-HRP
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9047R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9047R-A488
Lokale Artikelnummer::
BOSSBS-9047R-A488
Beschreibung:
Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-CY5
Lokale Artikelnummer::
BOSSBS-9067R-CY5
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9067R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9067R-FITC
Lokale Artikelnummer::
BOSSBS-9067R-FITC
Beschreibung:
Huntington disease is associated with the expansion of a polyglutamine tract, greater than 35 repeats, in the HD gene product, huntingtin. HIP1, a membrane-associated protein, binds specifically to the N-terminus of human huntingtin. HIP1 is ubiquitously expressed in different brain regions at low levels and exhibits nearly identical subcellular fractionation as huntingtin. The HIP1 gene locates to the human chromosome 7q11.23. The huntingtin-HIP1 interaction is restricted to the brain and is inversely correlated to the polyglutamine length in the huntingtin, suggesting that loss of normal huntingtin-HIP1 interaction may compromise the membrane-cytoskeletal integrity in the brain. HIP1 contains an endocytic multidomain protein with a C-terminal Actin-binding domain, a central coiled-coil forming region and an N-terminal ENTH domain. HIP1 may be involved in vesicle trafficking; the structural integrity of HIP1 is crucial for maintenance of normal vesicle size in vivo. HIP12 is a non-proapoptotic member of the HIP gene family that is expressed in the brain and shares a similar subcellular distribution pattern with HIP1. However, HIP12 differs from HIP1 in its pattern of expression at both the mRNA and protein level. HIP12 does not directly interact with huntingtin but can interact with HIP1.
VE:
1 * 100 µl
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noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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