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1,2-Phenylendiisothiocyanat
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1,2-Phenylendiisothiocyanat
Artikel-Nr:
(PRSI63-987)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
63-987
Lokale Artikelnummer::
PRSI63-987
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI26-543)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-543
Lokale Artikelnummer::
PRSI26-543
Beschreibung:
YAP1 is the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. YAP1 contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-037)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-037
Lokale Artikelnummer::
PRSI92-037
Beschreibung:
Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. As an inhibitor of cysteine proteinases, Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI61-052)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-052
Lokale Artikelnummer::
PRSI61-052
Beschreibung:
For IHC-P starting dilution is: 1:25. For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI6131)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6131
Lokale Artikelnummer::
PRSI6131
Beschreibung:
ZBTB9 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB9, also known as ZNF919, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB9, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB9 may act as a transcriptional repressor or be involved in tumorigenesis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI25-279)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-279
Lokale Artikelnummer::
PRSI25-279
Beschreibung:
ZNF136 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 14 C2H2-type zinc fingers and 1 KRAB domain. ZNF136 may be involved in transcriptional regulation as a weak repressor when alone, or a potent one when fused with a heterologous protein containing a KRAB B-domain.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-181)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-181
Lokale Artikelnummer::
PRSI26-181
Beschreibung:
UNC50 belongs to the unc-50 family. It binds RNA. UNC50 may be involved in cell surface expression of neuronal nicotinic receptors.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-436)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-436
Lokale Artikelnummer::
PRSI92-436
Beschreibung:
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PIP4K2A) is a member of the phosphatidylinositol-4-phosphate 5-kinase family. It contains 1 PIPK domain and is expressed ubiquitously, with high levels in the brain. It catalyses the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). It may exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. It may regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation, negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. It also involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-517)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-517
Lokale Artikelnummer::
PRSI92-517
Beschreibung:
Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and interleukin 1 beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. The mouse Il1rn gene encodes a 178 amino acids (aa) protein with a 26 aa signal peptide. Mouse Il1rn protein shares 26% and 19% identity with its homologues IL-1 beta and IL-1 alpha, respectively. Il1rn can Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signalling, but has no interleukin-1 like activity. Recently, an recombinant human Il1rn protein is used in the treatment of rheumatoid arthritis, an autoimmune disease in which IL-1 plays a key role.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-475)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-475
Lokale Artikelnummer::
PRSI90-475
Beschreibung:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth, and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1, and IL-6 by macrophages.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-494)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-494
Lokale Artikelnummer::
PRSI92-494
Beschreibung:
Vascular endothelial growth factor (VEGF/VEGF-A ) is originally known as vascular permeability factor (VPF). It belongs to the PDGF family with a cysteine-knot structure comprised of eight conserved cysteine residues, and reckoned as a potent mediator in the process of angiogenesis and vasculogenesis in either fetus or adult. VEGF is particularly expressed in supraoptic , paraventricular nuclei and the choroid plexus of the pituitary, and abundant in the corpus luteum of the ovary and in kidney glomeruli. The rat VEGF protein contains a putative 20 amino acids (aa) signal peptide, and alternative splicing of rat VEGF gene produces isoforms of 120, 144, 164 and 188 aa. Rat VEGF164 respectively displays 97% and 88% aa identity with that regions of mouse and human VEGF. VEGF can bind to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin, and play important roles in inducing endothelial cell proliferation, promoting cell migration, inhibiting apoptosis and inducing permeabilisation of blood vessels.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI2351P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2351P
Lokale Artikelnummer::
PRSI2351P
Beschreibung:
NAK peptide is used for blocking the activity of NAK/TBK1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-549)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-549
Lokale Artikelnummer::
PRSI90-549
Beschreibung:
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific recognition of phosphatidylserine (PtdSer), exposed on the surface of apoptotic cells. Tim-3, a type I transmembrane protein, contains an immunoglobulin and a mucin-like domain in its extracellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. TIM-3 is preferentially expressed on Th1 and Tc1 cells, and generates an inhibitory signal resulting in apoptosis of Th1 and Tc1 cells. TIM-3 is also expressed on some dendritic cells and can mediate phagocytosis of apoptotic cells and cross-presentation of antigen. Tim-3 functions to inhibit aggressive Th1-mediated auto- and alloimmune responses. Tim-3 pathway blockade by administration of Tim-3:Fc fusion protein accelerates diabetes in nonobese diabetic mice, causes hyperproliferation of Th1 cells and Th1 cytokine release in an experimental autoimmune encephalomyelitis (EAE) model and prevents acquisition of transplantation tolerance induced by costimulation blockade.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI33-448)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-448
Lokale Artikelnummer::
PRSI33-448
Beschreibung:
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI26-018)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-018
Lokale Artikelnummer::
PRSI26-018
Beschreibung:
The function of the LOC253012 protein remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI4447P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4447P
Lokale Artikelnummer::
PRSI4447P
Beschreibung:
RIM2 peptide is used for blocking the activity of RIM2 antibody.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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