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2-Benzyl-4,6-dichloropyrimidine
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2-Benzyl-4,6-dichloropyrimidine
Artikel-Nr:
(PRSI3045)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3045
Lokale Artikelnummer::
PRSI3045
Beschreibung:
p53DINP1 Antibody: Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible gene was identified recently and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein 1) and SIP (for stress induced protein) in human and mouse. A p53DINP1 antisense oligonucleotide inhibits and overexpression of p53DINP1 enhances Ser46 phosphorylation of p53, induction of p53AIP1, and cell death induced by DNA double-strand breaks. p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. The p53DINP1/SIP gene encodes two proteins of 27 and 18 kDa in human and mouse termed p53DINP1-alpha and p53DINP1-beta or SIP27 and SIP18. p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.
VE:
1 * 100 µG
Lieferant:
Merck
Beschreibung:
Vitamin E-Trockenpulver (50 g all-rac-α-Tocopherylacetat in 100 g Substanz)
Lieferant:
Thermo Scientific
Beschreibung:
4-Pentylbenzolsulfonylchlorid
Lieferant:
Sigma-Aldrich
Beschreibung:
Eisen(III)acetylacetonat, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Eisen(III)acetylacetonat, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
(±)-α-Tocopherol has been used for preparing mycobacterial emulsions. It has also been used to study its immunomodulatory effect on influenza virus.
Artikel-Nr:
(PRSI25-337)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-337
Lokale Artikelnummer::
PRSI25-337
Beschreibung:
SSX6 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy.The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-683)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-683
Lokale Artikelnummer::
PRSI92-683
Beschreibung:
Triggering receptor expressed on myeloid cells-2 (TREM-2) is a cell surface receptor primarily expressed on macrophages, osteoclasts, microglia and dendritic cells. TREM-2 is one member of the TREM family, inhibiting the releasing of inflammatory mediators, so it is an important in vivo anti-inflammatory receptor. TREM-2 consists of an 18 aa signal sequence, a 153 aa extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. A soluble form of TREM-2 (TREM-2b) created by alternate splicing diverges at aa 161. TREM-2 transduces intracellular signals through the adaptor DAP12. After binding of TREM-2 with ligand, the TREM-2/DAP12 (dead-cell-activated-receptor-associated protein)-mediated signal transduction pathway causes a series of intracellular protein tyrosine phosphorylation reactions and enzymatic reactions, which then activate the myeloid cells and participate T cell responses.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-682)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-682
Lokale Artikelnummer::
PRSI92-682
Beschreibung:
Triggering receptor expressed on myeloid cells-2 (TREM-2) is a cell surface receptor primarily expressed on macrophages, osteoclasts, microglia and dendritic cells. TREM-2 is one member of the TREM family, inhibiting the releasing of inflammatory mediators, so it is an important in vivo anti-inflammatory receptor. TREM-2 consists of an 18 aa signal sequence, a 153 aa extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. A soluble form of TREM-2 (TREM-2b) created by alternate splicing diverges at aa 161. TREM-2 transduces intracellular signals through the adaptor DAP12. After binding of TREM-2 with ligand, the TREM-2/DAP12 (dead-cell-activated-receptor-associated protein)-mediated signal transduction pathway causes a series of intracellular protein tyrosine phosphorylation reactions and enzymatic reactions, which then activate the myeloid cells and participate T cell responses.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI33-495)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-495
Lokale Artikelnummer::
PRSI33-495
Beschreibung:
Recognises a protein of 70 kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI4429)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4429
Lokale Artikelnummer::
PRSI4429
Beschreibung:
Cathelicidin Antibody: One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
VE:
1 * 100 µG
Artikel-Nr:
(PRSIPM-5317)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
PM-5317
Lokale Artikelnummer::
PRSIPM-5317
Beschreibung:
IRAK Monoclonal Antibody: Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-κB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).
VE:
1 * 100 µG
Lieferant:
Alfa Aesar
Beschreibung:
Zirkonylnitrat Hydrat ≥99,9% (Metall-Basis)
Lieferant:
EPPENDORF
Beschreibung:
Einfach handzuhabende, präzise Mikropipetten mit reduziertem Gewicht, speziell für professionelle Anforderungen und zur optimalen Unterstützung der täglichen Arbeit entwickelt. Mit einem intuitiven Bedienkonzept und einem Design, das auf dem bewährten Eppendorf PhysioCare® Konzept beruht.
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Zirkonylnitrat Hydrat
Artikel-Nr:
(34978-2.5L)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
34978-2.5L
Lokale Artikelnummer::
HONC34978-2.5L
Beschreibung:
Wasser mit 0,1% (v/v) Trifluoressigsäure, CHROMASOLV™ LC-MS LabReady™, Lösungsmittelgemisch für die LC-MS, Riedel-de Haën™
VE:
1 * 2,5 L
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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