2,4,6-Tris(brommethyl)mesitylen
Artikel-Nr:
(BOSSBS-0497R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0497R-CY7
Lokale Artikelnummer::
BOSSBS-0497R-CY7
Beschreibung:
Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0497R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0497R-A750
Lokale Artikelnummer::
BOSSBS-0497R-A750
Beschreibung:
Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Perfluorodecane 95%
Artikel-Nr:
(APOSOR310917-500MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR310917-500MG
Lokale Artikelnummer::
APOSOR310917-500MG
Beschreibung:
1-Ethoxy-3-methoxybenzene
VE:
1 * 500 mg
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 1934-21-0
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Lieferant:
VWR Collection
Beschreibung:
Polyurethanschaum.
Lieferant:
Bohlender
Beschreibung:
Adaptors, made of PTFE, white, allow the use of BOLA multiple distributors for bottles with female thread GL 45 also on bottles with GL 32, GL 40 and S 40 threads.
Lieferant:
Thermo Scientific
Beschreibung:
Appearance: Black Crystalline powder
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2-Amino-2-oxazoline hydrochloride 95%
Artikel-Nr:
(APOSOR28696-100G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR28696-100G
Lokale Artikelnummer::
APOSOR28696-100G
Beschreibung:
6-Nitroveratrumaldehyd 96%
VE:
1 * 100 g
Artikel-Nr:
(ABCAAB312834-100UL)
Lieferant:
Abcam
Beschreibung:
Anti-RAB12 (phospho S106) Rabbit Monoclonal Antibody [clone: EPR26018-45]
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Artikel-Nr:
(BOSSBS-11706R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11706R-CY5
Lokale Artikelnummer::
BOSSBS-11706R-CY5
Beschreibung:
The aldo-keto reductase 7 (AKR7) family includes AKR7A2, AKR7A3 and AKR7A4 in human, AKR7A5 in mouse and AKR7A2 in rat, all of which function in the metabolism of aflatoxin B(1) and other dicarbonyl-containing compounds. More specifically, AKR7A proteins are involved in the metabolism of compounds with ketone groups on adjacent carbon atoms in a broad range of tissues, notably the liver. The human AKR7A2 gene maps to human chromosome 1p35-36, a region frequently deleted in sporadic colorectal cancer. The functional significance of this correlation lies in the constitutive expression of AKR7A2 in human liver to eliminate aflatoxin (an environmental carcinogen), thus acting as an endogenous chemo-preventative agent.
VE:
1 * 100 µl
Preis auf Anfrage
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