4,4-Dimethylcyclohexa-1,5-dienylboronsäure Mononatriumsalz
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 18-35 kDa, identified as CD90 (also known as Thy1). CD90 is a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35 kDa) inserted into the cell membrane via a GPI anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblast and stromal cell lines, expressed on all thymocytes and peripheral T cells in mice, but in humans expressed only on small % fetal thymocytes, 10-40% of CD34 cells in bone marrow, and <1% of CD3 CD4 lymphocytes in peripheral circulation. It is also expressed by human lymph node HEV endothelium but not other endothelia. Lastly, it is expressed by a limited number of lymphoblastoid and leukemic cell lines.
Artikel-Nr:
(BOSSBS-11221R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11221R-CY5
Lokale Artikelnummer::
BOSSBS-11221R-CY5
Beschreibung:
SH3TC2 (SH3 domain and tetratricopeptide repeats 2) is a 1,288 amino acid protein that contains one SH3 domain and eight TPR repeats. The SH3TC2 gene encodes a protein expressed in Schwann cells of peripheral nerves, and localized to the plasma membrane and to the perinuclear endocytic recycling compartment, suggesting a possible function in myelination and/or in regions of axoglial interactions. The SH3TC2 protein is expressed in adult heart, testis, spinal cord, and brain as well as in fetal brain and liver. Mild mononeuropathy of the median nerve (MNMN) is caused by heterozygous mutation in the SH3TC2 gene. Also, Charcot-Marie-Tooth disease type 4C (CMT4C) is a more severe neuropathy caused by homozygous or compound heterozygous mutation in the SH3TC2 gene. Existing as four alternatively spliced isoforms and containing 18 exons, the SH3TC2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q32.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13528R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13528R-CY7
Lokale Artikelnummer::
BOSSBS-13528R-CY7
Beschreibung:
G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. GPRs all have seven membrane-spanning domains and extracellular loops that can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. SREB1 (super conserved receptor expressed in brain 1), also known as GPR27 (G protein-coupled receptor 27), belongs to the SREB subfamily of GPRs that are expressed in the central nervous system. SREB1 may function as an amine-like GPR.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI92-637)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-637
Lokale Artikelnummer::
PRSI92-637
Beschreibung:
Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF- gamma , which then stimulates 18BP production via NF-κB. The interaction between IL-18 and IL-18BP has a significant role in the inflammation process. IL-18 BPs have four isoforms, a, b, c and d, which are spliced by different ways. The IL-18 BP isoforms a and c each contain one immunoglobulin (Ig)-like C2-type domain which is essential to the binding and neutralizing properties of the binding proteins. The IL-18 BP isoforms b and d lack a complete Ig domain. The expression of IL-18 and the IL-18BP are unidentified in immune tissues such as the spleen, but also in nonimmune cells including keratinocytes.
VE:
1 * 50 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
Phenyllithium 1.8 mol/l in Di-n-butylether, Sigma-Aldrich®
Lieferant:
Bernd Kraft
Beschreibung:
Salzsäure 18% analytisches Reagens
Artikel-Nr:
(BOSSBS-11957R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11957R-HRP
Lokale Artikelnummer::
BOSSBS-11957R-HRP
Beschreibung:
SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK4 (SLIT and NTRK-like protein 4) is a 837 amino acid single-pass type I membrane protein that contains 18 LRR (leucine-rich) repeats and is expressed in neural tissues, specifically in the thalamus, hypothalamus, subventricular zone, CA3 region of the hippocampus and cortical plate. SLITRK4 may be upregulated in some astrocytic brain tumors such as glioblastomas, astrocytomas and primitive neuroectodermal tumors. As compared with its family member SLITRK2, SLITRK4 only weakly suppresses neurite outgrowth. A study using genome-wide transcriptional profiling suggested that the gene encoding SLITRK4, as well as the ARL5B and PLA2G7 genes, may be involved in the pathogenesis of preeclampsia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11221R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11221R-HRP
Lokale Artikelnummer::
BOSSBS-11221R-HRP
Beschreibung:
SH3TC2 (SH3 domain and tetratricopeptide repeats 2) is a 1,288 amino acid protein that contains one SH3 domain and eight TPR repeats. The SH3TC2 gene encodes a protein expressed in Schwann cells of peripheral nerves, and localized to the plasma membrane and to the perinuclear endocytic recycling compartment, suggesting a possible function in myelination and/or in regions of axoglial interactions. The SH3TC2 protein is expressed in adult heart, testis, spinal cord, and brain as well as in fetal brain and liver. Mild mononeuropathy of the median nerve (MNMN) is caused by heterozygous mutation in the SH3TC2 gene. Also, Charcot-Marie-Tooth disease type 4C (CMT4C) is a more severe neuropathy caused by homozygous or compound heterozygous mutation in the SH3TC2 gene. Existing as four alternatively spliced isoforms and containing 18 exons, the SH3TC2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q32.
VE:
1 * 100 µl
Lieferant:
Agilent
Beschreibung:
18 ml vials
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 70 kDa, which is identified as CD86 (HLDA V; WS Code BP BP072. HLDA V; WS Code A A109. HLDA VI; WS Code BP 95. HLDA VI; WS Code B CD86.9). CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
Artikel-Nr:
(BOSSBS-0344R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0344R-CY5.5
Lokale Artikelnummer::
BOSSBS-0344R-CY5.5
Beschreibung:
Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species jumping ability.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13528R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13528R
Lokale Artikelnummer::
BOSSBS-13528R
Beschreibung:
G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. GPRs all have seven membrane-spanning domains and extracellular loops that can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. SREB1 (super conserved receptor expressed in brain 1), also known as GPR27 (G protein-coupled receptor 27), belongs to the SREB subfamily of GPRs that are expressed in the central nervous system. SREB1 may function as an amine-like GPR.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR303494-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR303494-5G
Lokale Artikelnummer::
APOSOR303494-5G
Beschreibung:
4-(N,N-Diphenylamino)phenylboronsäurepinakolester
VE:
1 * 5 g
Artikel-Nr:
(USBI132060)
Lieferant:
US Biological
Hersteller-Artikelnummer::
132060
Lokale Artikelnummer::
USBI132060
Beschreibung:
Anti-PTPN18 Mouse Polyclonal Antibody
VE:
1 * 50 µG
Lieferant:
BECTON DICKINSON MEDICAL
Beschreibung:
Blood collection sets consist of a needle and a multi-sample Luer adapter, connected by several length of tubing. A Safety-Lok protective shield reduces needlestick risk.
Artikel-Nr:
(462-8559)
Lieferant:
GRANT INSTRUMENTS
Hersteller-Artikelnummer::
JBN18
Lokale Artikelnummer::
GRANJBN18
Beschreibung:
Diese digitalen Wasserbäder ohne Rührfunktion sind mit Kapazitäten von 5 bis 26 Litern verfügbar. Alle Einheiten haben Edelstahltanks und langlebige lackierte Stahlgehäuse, bieten schnelle Aufheizzeiten, eine gute Temperaturkontrolle, eine Verriegelung an der Vorderseite, benutzerfreundliche Bedienelemente und eine helle, übersichtliche Anzeige. Alle Bäder sind mit Heizmattentechnologie für einen optimalen Arbeitsbereich ausgestattet - ohne Heizelement im Tank sind sie leichter zu reinigen. Die größeren Modelle ab 12 Liter aufwärts verfügen über einen praktischen Ablaufhahn an der Vorderseite des Bads. Das Sortiment ist ideal für den Einsatz in Bildung und Ausbildung sowie in industriellen Anwendungen wie der Produkt- und Materialprüfung.
VE:
1 * 1 ST
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