Artikel-Nr:
(BOSSBS-9748R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9748R-FITC
Lokale Artikelnummer::
BOSSBS-9748R-FITC
Beschreibung:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1,200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9748R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9748R-HRP
Lokale Artikelnummer::
BOSSBS-9748R-HRP
Beschreibung:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1,200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12330R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12330R-CY7
Lokale Artikelnummer::
BOSSBS-12330R-CY7
Beschreibung:
The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. Staf-50 (50 kDa-stimulated trans-acting factor), also known as TRIM22 (tripartite motif-containing 22), RNF94 or GPSTAF50, is a 498 amino acid cytoplasmic protein that belongs to the TRIM family and, characteristic of TRIM family members, contains one RING-type zinc finger, one B box-type zinc finger and one SPRY domain. Induced by IFN-å and IFN-∫, Staf-50 is strongly expressed in ovary, spleen, thymus and peripheral blood leukocytes where it is thought to mediate the antiviral effects of IFN proteins. Additionally, Staf-50 is present in leukemic cells, suggesting a role in cancer formation and metastasis. Staf-50 exists as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 11.
VE:
1 * 100 µl
Lieferant:
PRAT DUMAS
Beschreibung:
Pure cotton cellulose
Lieferant:
Bernd Kraft
Beschreibung:
Diethylether stabilisiert, reinst
Artikel-Nr:
(BOSSBS-12495R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12495R-HRP
Lokale Artikelnummer::
BOSSBS-12495R-HRP
Beschreibung:
APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA. Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses. Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome. Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication. This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
VE:
1 * 100 µl
Artikel-Nr:
(732-4910)
Lieferant:
THERMO MATRIX TECHNOLOGIES
Hersteller-Artikelnummer::
AB-0932
Lokale Artikelnummer::
MATRAB-0932
Beschreibung:
PP. 96-Well-Platten mit runden Wells zur Lagerung und für Screening-Anwendungen.
VE:
1 * 50 ST
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Artikel-Nr:
(EHERC15990200)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C15990200
Lokale Artikelnummer::
EHERC15990200
Beschreibung:
trans-Permethrin
VE:
1 * 10 mg
Lieferant:
FLUOROCHEM
Beschreibung:
1,3-Bis(2-hydroxyhexafluorisopropyl)benzol
Lieferant:
Alfa Aesar
Beschreibung:
Thiamphenicol
Artikel-Nr:
(USBI044416)
Lieferant:
US Biological
Hersteller-Artikelnummer::
044416
Lokale Artikelnummer::
USBI044416
Beschreibung:
Anti-ZSCAN22 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(MOLE25317460-25G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
25317460-25G
Lokale Artikelnummer::
MOLE25317460-25G
Beschreibung:
p-Phenylendiacetonitril
VE:
1 * 25 g
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Lieferant:
DWK Life Sciences
Beschreibung:
These closures are made from pharmaceutical grade materials.
Artikel-Nr:
(761-0028)
Lieferant:
BREUKHOVEN
Hersteller-Artikelnummer::
15892
Lokale Artikelnummer::
BREU15892
Beschreibung:
Folding magnifier with three lenses with a magnification of 4×, 8× and 12×.
VE:
1 * 1 ST
Artikel-Nr:
(MOLE32742152-1KG)
Lieferant:
Molekula
Hersteller-Artikelnummer::
32742152-1KG
Lokale Artikelnummer::
MOLE32742152-1KG
Beschreibung:
Dichloressigsäure
VE:
1 * 1 kg
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