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Pyrazolo[1,5-a]pyrimidin-7(4H)-one
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Pyrazolo[1,5-a]pyrimidin-7(4H)-one
Artikel-Nr:
(BOSSBS-4280R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4280R-A488
Lokale Artikelnummer::
BOSSBS-4280R-A488
Beschreibung:
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2624R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2624R-HRP
Lokale Artikelnummer::
BOSSBS-2624R-HRP
Beschreibung:
Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6947R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6947R-CY5.5
Lokale Artikelnummer::
BOSSBS-6947R-CY5.5
Beschreibung:
KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8034R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8034R-CY5
Lokale Artikelnummer::
BOSSBS-8034R-CY5
Beschreibung:
Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.Tissue specificity:Ubiquitous. Highest expression in the liver, with lower expression in brain, lung, placenta, pancreas, small intestine, heart, skeletal muscle, kidney and placenta.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15552R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15552R
Lokale Artikelnummer::
BOSSBS-15552R
Beschreibung:
This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4280R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4280R-CY5.5
Lokale Artikelnummer::
BOSSBS-4280R-CY5.5
Beschreibung:
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4280R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4280R-CY3
Lokale Artikelnummer::
BOSSBS-4280R-CY3
Beschreibung:
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5145R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5145R-CY3
Lokale Artikelnummer::
BOSSBS-5145R-CY3
Beschreibung:
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15552R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15552R-CY7
Lokale Artikelnummer::
BOSSBS-15552R-CY7
Beschreibung:
This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13475R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13475R-A680
Lokale Artikelnummer::
BOSSBS-13475R-A680
Beschreibung:
Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0039R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0039R-CY7
Lokale Artikelnummer::
BOSSBS-0039R-CY7
Beschreibung:
The activity dependent neuroprotective protein (ADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers. ADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells. ADNP is implicated in maintaining cell survival, perhaps through modulation of p53. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor.
VE:
1 * 100 µl
Artikel-Nr:
(90020.)
Lieferant:
Biotium
Hersteller-Artikelnummer::
90020
Lokale Artikelnummer::
BTIU90020
Beschreibung:
FITC (fluorescein-5-isothiocyanate) is an amine-reactive fluorescein derivative for labeling proteins or other molecules containing primary amines.
VE:
1 * 500 mg
Lieferant:
Biotium
Beschreibung:
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Artikel-Nr:
(BOSSBS-0235R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0235R-HRP
Lokale Artikelnummer::
BOSSBS-0235R-HRP
Beschreibung:
PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3979R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3979R-HRP
Lokale Artikelnummer::
BOSSBS-3979R-HRP
Beschreibung:
ENO3 is also known as beta enolase, one of the three enolase isoenzymes found in mammals. A switch from alpha enolase to beta enolase occurs in muscle tissue during development and ENO3, a homodimer, is found in skeletal muscle cells in the adult and appears to have a function in striated muscle development and regeneration. Mutations can result in decreased stability of the enzyme and be associated with a glycogen storage myopathy. This results in exercise-induced myalgias, generalized muscle weakness and fatigability.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5144R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5144R-HRP
Lokale Artikelnummer::
BOSSBS-5144R-HRP
Beschreibung:
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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