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7-Hydroxy-4-(3-trifluoromethylphenyl)coumarin
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7-Hydroxy-4-(3-trifluoromethylphenyl)coumarin
Lieferant:
SEMADENI
Beschreibung:
Disposable cuvettes for photometric measurements in the visible range (350 to 800 nm).
Lieferant:
SEMADENI
Beschreibung:
Unterteilungen, PS für Lagerboxen, grau, 322×108 mm, 45 mm Höhe
Artikel-Nr:
(PRSI3119)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3119
Lokale Artikelnummer::
PRSI3119
Beschreibung:
ATR Antibody: The Anthrax toxin receptor (ATR) was initially discovered as the tumor endothelial marker 8 (TEM8). This protein, which exists in three isoforms (36, 40, and 60 kDa), is highly expressed in tumor vessels as well as in the vasculature of developing embryos, suggesting that it may normally play a role in angiogenesis. However, it also acts as the receptor for anthrax toxin. Following the binding of this protein by the protective antigen (PA) of anthrax, PA is cleaved and heptamerizes to form the binding site for both edema factor (EF) and lethal factor (LF). This complex is then endocytosed by the cell; acidification in endosomes allows the release of EF and LF into the cytoplasm where they interfere with MAPK signaling and induce apoptosis.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI3117)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3117
Lokale Artikelnummer::
PRSI3117
Beschreibung:
ATR Antibody: The Anthrax toxin receptor (ATR) was initially discovered as the tumor endothelial marker 8 (TEM8). This protein, which exists in three isoforms (36, 40, and 60 kDa), is highly expressed in tumor vessels as well as in the vasculature of developing embryos, suggesting that it may normally play a role in angiogenesis. However, it also acts as the receptor for anthrax toxin. Following the binding of this protein by the protective antigen (PA) of anthrax, PA is cleaved and heptamerizes to form the binding site for both edema factor (EF) and lethal factor (LF). This complex is then endocytosed by the cell; acidification in endosomes allows the release of EF and LF into the cytoplasm where they interfere with MAPK signaling and induce apoptosis.
VE:
1 * 100 µG
Artikel-Nr:
(QUTW1092)
Lieferant:
QUARTZTECHNISCHE WERKSTATTEN
Hersteller-Artikelnummer::
1092
Lokale Artikelnummer::
QUTW1092
Beschreibung:
These crucibles and lids are made from quartzglas.
VE:
1 * 1 ST
Artikel-Nr:
(USBI039994)
Lieferant:
US Biological
Hersteller-Artikelnummer::
039994
Lokale Artikelnummer::
USBI039994
Beschreibung:
Anti-PI3KCB Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(PRSI7163)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7163
Lokale Artikelnummer::
PRSI7163
Beschreibung:
DHX36 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.
VE:
1 * 100 µG
Lieferant:
Thermo Scientific
Beschreibung:
6-Nitroveratrumaldehyd
Artikel-Nr:
(MARI1800002)
Lieferant:
MARIENFELD
Hersteller-Artikelnummer::
1800002
Lokale Artikelnummer::
MARI1800002
Beschreibung:
Färbeplatte, Glas, B×T×H: 89×57×4,5 mm, Anzahl Wells: 12, Lochgröße: Ø×H: 15×1,5 mm
VE:
1 * 12 ST
Artikel-Nr:
(LENZ07105600)
Lieferant:
Lenz Laborglas GmbH & CO.KG
Hersteller-Artikelnummer::
07105600
Lokale Artikelnummer::
LENZ07105600
Beschreibung:
Pouring rings are made of ETFE.
VE:
1 * 10 ST
Lieferant:
ATLAS - the shoe company
Beschreibung:
Lightweight ESD safety shoe made from perforated Sportline upper (oiled nubuck leather), breathable functional lining and a MPU® Light sole (3,5 mm profile, oil, acid and petrol resistant, anti-static).
Artikel-Nr:
(114-0266)
Lieferant:
HONEYWELL SAFETY
Hersteller-Artikelnummer::
6000310/45
Lokale Artikelnummer::
DALL6000310/45
Beschreibung:
Einlegesohle aus blauem Vlies.
VE:
1 * 10 PAAR
Artikel-Nr:
(SIAL237655-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
237655-1G
Lokale Artikelnummer::
SIAL237655-1G
Beschreibung:
(-)-DIOP, Sigma-Aldrich®
VE:
1 * 1 g
Artikel-Nr:
(PRSI33-895)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-895
Lokale Artikelnummer::
PRSI33-895
Beschreibung:
Recognises a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
VE:
1 * 100 µG
New Product
Lieferant:
BROEN-LAB
Beschreibung:
Augenduschen zur Wandbefestigung. Mit einem oder zwei Duschköpfen im 45°-Winkel.
Artikel-Nr:
(BOSSBS-5566R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5566R-A555
Lokale Artikelnummer::
BOSSBS-5566R-A555
Beschreibung:
Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'. Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1. Plays a direct role in the negative feedback regulation of the BCR signaling, by down-modulating BTK function via direct phosphorylation of BTK at 'Ser-180', which results in the alteration of BTK plasma membrane localization and in turn inhibition of BTK activity. Involved in apoptosis following oxidative damage: in case of oxidative conditions, specifically phosphorylates 'Ser-36' of isoform p66Shc of SHC1, leading to mitochondrial accumulation of p66Shc, where p66Shc acts as a reactive oxygen species producer. Acts as a coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and specifically mediating phosphorylation of 'Thr-6' of histone H3 (H3T6ph), a specific tag for epigenetic transcriptional activation that prevents demethylation of histone H3 'Lys-4' (H3K4me) by LSD1/KDM1A. In insulin signaling, may function downstream of IRS1 in muscle cells and mediate insulin-dependent DNA synthesis through the RAF1-MAPK/ERK signaling cascade. May participate in the regulation of glucose transport in adipocytes by negatively modulating the insulin-stimulated translocation of the glucose transporter SLC2A4/GLUT4.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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