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[2-(3,4-Dimethylphenoxy)phenyl]methanol


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Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-6659R-A750
Lokale Artikelnummer:: BOSSBS-6659R-A750
Beschreibung:   Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarised intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.
VE:  1 * 100 µl
Lieferant:  Biotium
Beschreibung:   Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule; two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-6659R-A555
Lokale Artikelnummer:: BOSSBS-6659R-A555
Beschreibung:   Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.
VE:  1 * 100 µl
Lieferant:  APOLLO SCIENTIFIC
Beschreibung:   3-Brom-5-(trifluormethoxy)anilin 99%

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-6613R-A750
Lokale Artikelnummer:: BOSSBS-6613R-A750
Beschreibung:   Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
VE:  1 * 100 µl
Artikel-Nr: (BOSSBS-12149R-CY5)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-12149R-CY5
Lokale Artikelnummer:: BOSSBS-12149R-CY5
Beschreibung:   DBX2 is a 339 amino acid member of the H2.0 homeobox family. DBX2, which is localized to the nucleus, contains one homeobox DNA-binding domain, a region of 60 amino acids that binds DNA through a helix-turn-helix type of structure. DBX2, which is expressed in the forebrain, midbrain, hindbrain and spinal cord, has been implicated in CNS development.Specifically, DBX2 has been shown to play a role in spinal cord dorsal/ventral patterning, as well as the regionalization of the CNS. DBX2 is also thought to play a role in the production of multiple spinal cord cell types.
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-13618R-CY7
Lokale Artikelnummer:: BOSSBS-13618R-CY7
Beschreibung:   A variety of morphological and molecular changes are required for mature spermatozoa formation. These steps are temporally guided by the transcription and translation of several testis-specific genes. SPANX (sperm protein associated with the nucleus, X-linked) family members are sperm- and testis-specific proteins containing between 97-103 amino acids, whose genes form a cluster on chromosome X. Sharing a high level of sequence similarity, SPANX-A, -B, -C, -D and -E localize to both cytoplasm and nucleus where they are associated with nuclear craters. SPANX-B (Sperm protein associated with the nucleus on the X chromosome B/F) is a 103 amino acid protein that is detected in round and elongating spermatids.
VE:  1 * 100 µl
Lieferant:  APOLLO SCIENTIFIC
Beschreibung:   (S)-(+)-1,2,3,4-Tetrahydro-1-naphthylamin
Artikel-Nr: (APOSOR302365-1G)

Lieferant:  APOLLO SCIENTIFIC
Hersteller-Artikelnummer:: OR302365-1G
Lokale Artikelnummer:: APOSOR302365-1G
Beschreibung:   5-Aminoisoquinolin-1(2H)-one
VE:  1 * 1 g
Lieferant:  Bioworld Technology
Hersteller-Artikelnummer:: BS1849
Lokale Artikelnummer:: BWRLBS1849
Beschreibung:   Synthetic peptide, corresponding to amino acids 300-350 of Human Casein Kinase Ialpha.
VE:  1 * 100 µG
Lieferant:  Bioworld Technology
Hersteller-Artikelnummer:: BS2968
Lokale Artikelnummer:: BWRLBS2968
Beschreibung:   Synthetic peptide, corresponding to amino acids 300-350 of Human AVP Receptor V3.
VE:  1 * 100 µG
Lieferant:  Bioworld Technology
Hersteller-Artikelnummer:: BS2485
Lokale Artikelnummer:: BWRLBS2485
Beschreibung:   Synthetic peptide, corresponding to amino acids 380-432 of Human TAF II p100.
VE:  1 * 100 µG

Lieferant:  Thermo Scientific
Hersteller-Artikelnummer:: 441095000
Lokale Artikelnummer:: ACRO441095000
Beschreibung:   (S)-N-Fmoc-α-methyl-2-fluorophenylalanine 98%, 98% ee
VE:  1 * 500 mg
Lieferant:  Thermo Scientific
Beschreibung:   3,3',5,5'-Tetramethylbenzidin (TMB) EASY, flüssiges Substrat
Artikel-Nr: (BOSSBS-11213R-CY3)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-11213R-CY3
Lokale Artikelnummer:: BOSSBS-11213R-CY3
Beschreibung:   The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a 522 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and contains ten LRR repeats. Expressed predominately in forebrain tissue, LRRTM1 is thought to be involved in the development of forebrain structures, specifically by influencing axon trafficking, as well as neuronal differentiation and connectivity. Human LRRTM1 shares 96% amino acid identity with its mouse counterpart, suggesting a conserved role between species. Defects in the gene encoding LRRTM1 may be associated with the pathogenesis of several common neurodevelopmental disorders.
VE:  1 * 100 µl
Artikel-Nr: (BOSSBS-9520R-CY5.5)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-9520R-CY5.5
Lokale Artikelnummer:: BOSSBS-9520R-CY5.5
Beschreibung:   Dyrk (for dual specificity tyrosine phosphorylation regulated kinase) is the homolog of the Drosophila mnb (minibrain) gene, which is required for neurogenesis. Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, which is itself regulated by tyrosine phosphorylation. Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases. Dyrk family members, including Dyrk1A (originally Dyrk), Dyrk1B, Dyrk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, are thought to be involved in diverse cellular functions. Two isoforms of human fetal brain Dyrk2 exist: a deduced 528-amino acid protein and a protein containing 73 additional amino acids at the amino terminus. Dyrk3 is strongly expressed in testis, only after the onset of spermatogenesis, and very weakly expressed in spleen and adrenal gland. The genes which encode Dyrk2 and Dyrk3 map to human chromosomes 12 and 1q32, respectively.
VE:  1 * 100 µl
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