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2-Amino-5-bromo-3-fluorophenol
Artikel-Nr:
(PRSI92-373)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-373
Lokale Artikelnummer::
PRSI92-373
Beschreibung:
Hyaluronan-binding protein 2（HABP2） is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator to the active two chain form, activates coagulation factor VII.
VE:
1 * 50 µG
Artikel-Nr:
(86838-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
86838-5G
Lokale Artikelnummer::
SUPL86838-5G
Beschreibung:
Tetrabutylammonium bis-trifluoromethanesulphonimidate ≥99,0% (durch NMR) für die Elektronikindustrie, Supelco®
VE:
1 * 5 g
Artikel-Nr:
(8.14528.0100)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.14528.0100
Lokale Artikelnummer::
MERC8.14528.0100
Beschreibung:
Bis(8-hydroxychinolinium)sulfat Monohydrat, Sigma-Aldrich®
VE:
1 * 100 g
Artikel-Nr:
(PRSI33-581)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-581
Lokale Artikelnummer::
PRSI33-581
Beschreibung:
It recognises a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesised on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesised N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PIER21650)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
21650
Lokale Artikelnummer::
PIER21650
Beschreibung:
Thermo Scientific Pierce Sulfo-LC-SPDP is a water-soluble, long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteines.
VE:
1 * 50 mg
Artikel-Nr:
(1802-50ML)
Lieferant:
SIGMA ALDRICH MICROSCOPY
Hersteller-Artikelnummer::
1802-50ML
Lokale Artikelnummer::
SIAM1802-50ML
Beschreibung:
Naphthol AS-BI Phosphoric acid solution for use in the Sigma Lymphocyte Enzyme (Acid Phosphatase) Procedure, No. 181A.
VE:
1 * 50 mL
Artikel-Nr:
(8.41875.0001)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.41875.0001
Lokale Artikelnummer::
MERC8.41875.0001
Beschreibung:
1,4-Bis(2-methylstyryl)benzene zur Synthese, Sigma-Aldrich®
VE:
1 * 1 g
Lieferant:
Merck
Beschreibung:
Bis(triphenylphosphin)palladium(II)chlorid zur Synthese, Sigma-Aldrich®
Artikel-Nr:
(PRSI91-360)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-360
Lokale Artikelnummer::
PRSI91-360
Beschreibung:
Recombinant Human Urokinase-Type Plasminogen Activator is a serine protease, which specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. Urokinase-Type Plasminogen Activator is a potent marker of invasion and metastasis in many human cancers associated with breast, colon, stomach, bladder, brain, ovary and endometrium. Human Urokinase-Type Plasminogen Activator is initially synthesized as 431 amino acid precursor with a N-terminal signal peptide residues. The single chain molecule is processed into a disulfide-linked two-chain molecule. There exists two forms A chain, the long A chain contains an EGF-like domain that is responsible for binding of the uPA receptor. The B chain corresponds to the catalytic domain.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-380)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-380
Lokale Artikelnummer::
PRSI91-380
Beschreibung:
Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI40-612)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
40-612
Lokale Artikelnummer::
PRSI40-612
Beschreibung:
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Due to its increased acidity, VEGF121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates. Recombinant human VEGF121 is a 28.4 kDa disulfide-linked homodimeric protein consisting of two 121 amino acid polypeptide chains.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI91-572)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-572
Lokale Artikelnummer::
PRSI91-572
Beschreibung:
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI33-824)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-824
Lokale Artikelnummer::
PRSI33-824
Beschreibung:
It recognises a ~85-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This mAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
VE:
1 * 100 µG
New Product
Lieferant:
MP Biomedicals
Beschreibung:
Inhibitors: p-Chloromercuribenzoate, lodoacetamide, heavy metal ions (Zn²⁺, Fe²⁺, Zn²⁺, Cd²⁺, Cu²⁺, Pb²⁺, Ag⁺, Hg²⁺), Ionic Detergents (SDS, DAC, etc.). Contaminants: The preparation is practically free from other glycosidases (a-galactosidase, a-,b-glucosidase, a-,b-mannosidase, etc.) and proteinase. Principle: o-Nitrophenyl-b-D-galactopyranoside (ONPG) b-galactosidase > <i>o</i>-Nitrophenol (ONP) +D-Galactose. The appearance of o-nitrophenol is measured at 410 nm by spectrophotemetry. Thermal stability: below 50 °C (pH 7,3; 15 min) (Lit.), Optimum Temperature: 50 to 55 °C (Lit.).
Artikel-Nr:
(78268-1ML-F)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
78268-1ML-F
Lokale Artikelnummer::
SUPL78268-1ML-F
Beschreibung:
N-Methyl-bis-heptafluorobutyramide (MBHFBA) ≥96,0% (durch GC), LiChropur™ zur GC-Derivatisierung, Supelco®
VE:
1 * 1 mL
Artikel-Nr:
(PRSI25-948)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-948
Lokale Artikelnummer::
PRSI25-948
Beschreibung:
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity.Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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