4-Fluorobenzo[d]thiazol-2(3H)-one
Artikel-Nr:
(BOSSBS-0651R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0651R-CY7
Lokale Artikelnummer::
BOSSBS-0651R-CY7
Beschreibung:
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5866R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5866R-A350
Lokale Artikelnummer::
BOSSBS-5866R-A350
Beschreibung:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6947R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6947R-A680
Lokale Artikelnummer::
BOSSBS-6947R-A680
Beschreibung:
KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerises with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8034R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8034R-FITC
Lokale Artikelnummer::
BOSSBS-8034R-FITC
Beschreibung:
Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.Tissue specificity:Ubiquitous. Highest expression in the liver, with lower expression in brain, lung, placenta, pancreas, small intestine, heart, skeletal muscle, kidney and placenta.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7504R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7504R
Lokale Artikelnummer::
BOSSBS-7504R
Beschreibung:
Laminin S binds to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin S is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Beta 2 is a subunit of laminin 3 (Laminin S), laminin 4 (S merosin), and laminin 7 (KS laminin).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13335R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13335R
Lokale Artikelnummer::
BOSSBS-13335R
Beschreibung:
Genethonin-1 is a 358 amino acid single-pass type III membrane protein that contains one CBM20 (carbohydrate binding type-20) domain. A hydrophobic protein, Genethonin-1 is highly expressed in cardiac and skeletal muscle and is found at moderate levels in placenta and liver. Genethonin-1 and is thought to function in carbohydrate binding. The gene encoding Genethonin-1 maps to human chromosome 4, which represents approximately 6% of the human genome, contains nearly 900 genes and is associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8345R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8345R-HRP
Lokale Artikelnummer::
BOSSBS-8345R-HRP
Beschreibung:
FOP, is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8345R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8345R-FITC
Lokale Artikelnummer::
BOSSBS-8345R-FITC
Beschreibung:
FOP, is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12343R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12343R
Lokale Artikelnummer::
BOSSBS-12343R
Beschreibung:
TRB-1 is a 372 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase superfamily. Expressed ubiquitously with highest expression in bone marrow, thyroid gland, skeletal muscle and pancreas, TRB-1 interacts with MAPK kinases and is thought to regulate the activation of MAP kinses, possibly controlling MAP kinase cascades. The gene encoding TRB-1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12879R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12879R
Lokale Artikelnummer::
BOSSBS-12879R
Beschreibung:
Borrelia burgdorferi is a spirochete and the cause of Lyme disease, a tick transmitted illness of humans and animals. B. burgdorferi may persist in humans and animals for months or years following initial infection, despite a robust humoral immune response. B. burgdorferi resembles other spirochetes in that it is a highly specialized, motile, two-membrane, spiral shaped bacteria which lives primarily as an extracellular pathogen. B. burgdorferi has an unusual genome compared with other eubacteria which includes a linear chromosome approximately one megabase in size and numerous linear and circular plasmids.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12343R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12343R-FITC
Lokale Artikelnummer::
BOSSBS-12343R-FITC
Beschreibung:
TRB-1 is a 372 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase superfamily. Expressed ubiquitously with highest expression in bone marrow, thyroid gland, skeletal muscle and pancreas, TRB-1 interacts with MAPK kinases and is thought to regulate the activation of MAP kinses, possibly controlling MAP kinase cascades. The gene encoding TRB-1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12528R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12528R-HRP
Lokale Artikelnummer::
BOSSBS-12528R-HRP
Beschreibung:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8345R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8345R
Lokale Artikelnummer::
BOSSBS-8345R
Beschreibung:
FOP, is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1876R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1876R-A555
Lokale Artikelnummer::
BOSSBS-1876R-A555
Beschreibung:
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12528R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12528R-CY7
Lokale Artikelnummer::
BOSSBS-12528R-CY7
Beschreibung:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1876R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1876R-A350
Lokale Artikelnummer::
BOSSBS-1876R-A350
Beschreibung:
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
VE:
1 * 100 µl
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