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5,5'-Dibrom-2,2'-bithiophen
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5,5'-Dibrom-2,2'-bithiophen
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of 55-62 kDa, identified as cyclin B1. In mammals, cyclin B associates with inactive p34cdc2, which facilitates phosphorylation of p34cdc2 at aa 14Thr and 15Tyr. This maintains the inactive state until the end of G2-phase. The inactive cyclin B-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, when Cdc25, a specific protein phosphatase, dephosphorylates aa 14Thr and 15Tyr of p34cdc2 rendering the complex active at the G2/M boundary. This mitotic kinase complex remains active until the metaphase/anaphase transition when cyclin B is degraded. This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis. So, cyclin B-p34cdc2 plays a critical role in G2 to M transition.
Artikel-Nr:
(BOSSBS-7047R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7047R-HRP
Lokale Artikelnummer::
BOSSBS-7047R-HRP
Beschreibung:
Fibroblast growth factor-1 also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithe-lial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10–FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9035R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9035R
Lokale Artikelnummer::
BOSSBS-9035R
Beschreibung:
Pyridoxal kinase belongs to the pyridoxine kinase family and phosphorylates vitamin B6, a step necessary for the conversion of vitamin B6 to pyridoxal 5’ phosphate (PLP), the active form of vitamin B6. PLP acts as a coenzyme and functions to maintain homeostasis. Pyridoxal kinase is a 312-amino acid cytoplasmic protein that may act as a homodimer and is expressed ubiquitously. There are three known isoforms of pyridoxal kinase, and isoform 3 expression is observed in adult testis and spermatozoa. The optimum pH for pyridoxal kinase is between 5.5 and 6.0. PDXK, the gene that encodes the pyridoxal kinase protein, maps to chromosome 21q22.3 and may be a candidate gene for autoimmune polyglandular disease type 1, a genetic disorder that has been mapped to the same region on chromosome 21.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9035R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9035R-CY7
Lokale Artikelnummer::
BOSSBS-9035R-CY7
Beschreibung:
Pyridoxal kinase belongs to the pyridoxine kinase family and phosphorylates vitamin B6, a step necessary for the conversion of vitamin B6 to pyridoxal 5’ phosphate (PLP), the active form of vitamin B6. PLP acts as a coenzyme and functions to maintain homeostasis. Pyridoxal kinase is a 312-amino acid cytoplasmic protein that may act as a homodimer and is expressed ubiquitously. There are three known isoforms of pyridoxal kinase, and isoform 3 expression is observed in adult testis and spermatozoa. The optimum pH for pyridoxal kinase is between 5.5 and 6.0. PDXK, the gene that encodes the pyridoxal kinase protein, maps to chromosome 21q22.3 and may be a candidate gene for autoimmune polyglandular disease type 1, a genetic disorder that has been mapped to the same region on chromosome 21.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9035R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9035R-A488
Lokale Artikelnummer::
BOSSBS-9035R-A488
Beschreibung:
Pyridoxal kinase belongs to the pyridoxine kinase family and phosphorylates vitamin B6, a step necessary for the conversion of vitamin B6 to pyridoxal 5’ phosphate (PLP), the active form of vitamin B6. PLP acts as a coenzyme and functions to maintain homeostasis. Pyridoxal kinase is a 312-amino acid cytoplasmic protein that may act as a homodimer and is expressed ubiquitously. There are three known isoforms of pyridoxal kinase, and isoform 3 expression is observed in adult testis and spermatozoa. The optimum pH for pyridoxal kinase is between 5.5 and 6.0. PDXK, the gene that encodes the pyridoxal kinase protein, maps to chromosome 21q22.3 and may be a candidate gene for autoimmune polyglandular disease type 1, a genetic disorder that has been mapped to the same region on chromosome 21.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 55 kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1 adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.
Artikel-Nr:
(87896.180)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC87896.180
Beschreibung:
Wolframatophosphorsäure 22% in Orthophosphorsäure 11% Reag. Ph. Eur. 1065200
VE:
1 * 100 mL
Artikel-Nr:
(8.15031.0005)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.15031.0005
Lokale Artikelnummer::
MERC8.15031.0005
Beschreibung:
Diethylether-[D10] (99% D) für die Kernresonanzspektroskopie
VE:
1 * 5 mL
Artikel-Nr:
(BOSSBS-12976R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12976R-CY7
Lokale Artikelnummer::
BOSSBS-12976R-CY7
Beschreibung:
Acid ceramidase catalyzes the degradation of ceramide in normal tissues, and deficiency leads to accumulation of ceramide in tissues, a hallmark of Farber disease. Effected individuals experience early onset joint problems and neurological problems, owing to mutations in the acid ceramidase gene. Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma. In addition to ceramide hydrolysis, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates. Interestingly, pH regulates which reaction is favored; for hydrolysis the pH optimum is 4.5, whereas for the reverse reaction favors a pH of 5.5, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism.
VE:
1 * 100 µl
Artikel-Nr:
(ROCKABTS-100)
Lieferant:
Rockland Immunochemicals
Hersteller-Artikelnummer::
ABTS-100
Lokale Artikelnummer::
ROCKABTS-100
Beschreibung:
ABTS ELISA Peroxidase Substrate (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)) is a chromogenic substrate use to visualize reactivity of certain enzymes, particularly in immunosorbent assays. ABTS ELISA Peroxidase Substrate is commonly used with peroxidases, but is amenable to many other enzymes. In the presence of active enzyme, the substrate becomes a soluble green product detectable at 405nm.
VE:
1 * 100 mL
Lieferant:
Merck
Beschreibung:
Diethylentriamin zur Synthese, Sigma-Aldrich®
Artikel-Nr:
(J60461.AP)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
J60461.AP
Lokale Artikelnummer::
ALFAJ60461.AP
Beschreibung:
3,3',5,5'-Tetramethylbenzidin (TMB)-Lösung, normale Empfindlichkeit anwendungsbereit, mit gemischter Anzeige
VE:
1 * 500 mL
Artikel-Nr:
(45713-250MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
45713-250MG
Lokale Artikelnummer::
SUPL45713-250MG
Beschreibung:
Organic Standard, TBTC
VE:
1 * 250 mg
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
(4S)-2,2-Dioxido-4- isopropyl -1,2,3-oxathiazolidine, N-BOC protected
Artikel-Nr:
(BLDPBD01188634-250)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD01188634-250
Lokale Artikelnummer::
BLDPBD01188634-250
Beschreibung:
(4S,4'S,5R,5'R)-2,2'-(Ethane-1,1-diyl)bis(4,5-diphenyl-4,5-dihydrooxazole) 97%
VE:
1 * 250 mg
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 55 kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.This MAb was characterized as human CD4 antibody at II and IV International Workshop on Human Leukocyte Differentiation Antigens.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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