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6,7-Dimethylchinolin-2,3-dicarbons\u00E4ure
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6,7-Dimethylchinolin-2,3-dicarbons\u00E4ure
Artikel-Nr:
(COBBHC-2558-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
HC-2558-1G
Lokale Artikelnummer::
COBBHC-2558-1G
Beschreibung:
2-(3-Brom-4-(trifluormethoxy)phenyl)-2,2-difluoressigsäure
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(PRSI92-376)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-376
Lokale Artikelnummer::
PRSI92-376
Beschreibung:
Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein, which is produced by normal alveolar macrophages and granulocytes, can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4, SPATA13 and APC via the JNK signalling pathway in colorectal tumour cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healling, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis.
VE:
1 * 50 µG
Artikel-Nr:
(SIAL374067-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
374067-25G
Lokale Artikelnummer::
SIAL374067-25G
Beschreibung:
Natriumchlordifluoracetat, Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-13536R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13536R-CY3
Lokale Artikelnummer::
BOSSBS-13536R-CY3
Beschreibung:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
VE:
1 * 100 µl
Lieferant:
VITLAB
Beschreibung:
LDPE, mit VENT CAP-Verschraubung.
Artikel-Nr:
(573100-100)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
573100-100
Lokale Artikelnummer::
CALB573100-100
Beschreibung:
A useful agent for introducing thiol groups, in protected form, into various proteins. Reacts with primary amines to add protected sulfhydryl groups. When treated with hydroxylamine, yields a free sulfhydryl group that can be conjugated to maleimide-modified proteins.
VE:
1 * 100 mg
Lieferant:
DRAEGER
Beschreibung:
Mit den Kurzzeitröhrchen können zahlreiche verschiedene Gase und Dämpfe festgestellt gemessen werden. Sie werden z. B. zur Bestimmung von Konzentrationsspitzen, zur Messung der persönlichen Belastung im Einatembereich, zur Ermittlung von Leckagen an Rohrleitungen und Gasanlagen sowie zur Luftanalyse in Abwasserkanälen, Schächten, Tanks oder engen Räumen eingesetzt.
Artikel-Nr:
(UPCHP-298)
Lieferant:
UPCHURCH SCIENTIFIC
Hersteller-Artikelnummer::
P-298
Lokale Artikelnummer::
UPCHP-298
Beschreibung:
These tools made from aluminium or Delrin® can be used to tighten most knurled nuts in hard to reach places. For precise tightening, the extender tools listed with ¼" hex drives are designed to adapt to any torque wrench with a female ¼" socket.
VE:
1 * 1 ST
Lieferant:
FLUOROCHEM
Beschreibung:
(±)-4-(Trifluormethyl)mandelsäure
Lieferant:
DOEHLER GROUP
Beschreibung:
Selektive Flüssigmedien zum qualitativen Nachweis von getränkeverderbenden Mikroorganismen. SSL Bouillon und OFS Agar geeignet für Ihre Analysen von: • alkoholfreie Getränke pH <4,5, einschließlich Fruchtsäften
• Bier-, Wein- und Milchmischgetränke • Fruchtsaftkonzentrate • Getränkegrundstoffe • Getränkepulver und -extrakte • Zucker • Spülwasserproben • Membranfiltrierte Proben Mit der gebrauchsfertigen SSL Bouillon können säuretolerante Mikroorganismen wie Milchsäurebakterien, Essigsäurebakterien, Hefen und Schimmelpilze aus alkoholfreien Getränken kultiviert werden. Sie erlaubt die Anreicherung auch von großen Probenvolumen. SSL Bouillon kann auch zur Voranreicherung mit einem Nachweis auf OFS Agar eingesetzt werden. SSL Bouillon und OFS Agar bieten folgende Anwendervorteile:
Artikel-Nr:
(BOSSBS-13536R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13536R-FITC
Lokale Artikelnummer::
BOSSBS-13536R-FITC
Beschreibung:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13536R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13536R-CY7
Lokale Artikelnummer::
BOSSBS-13536R-CY7
Beschreibung:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
VE:
1 * 100 µl
Artikel-Nr:
(113-2801)
Lieferant:
Thermo Fisher Scientific
Hersteller-Artikelnummer::
6356-0001
Lokale Artikelnummer::
NALG6356-0001
Beschreibung:
PC/Acetat mit Magnetfuß, transparent, Stärke: 3 mm. Das Schutzschild mit flexiblem Arm lässt sich einfach an Arbeitsflächen, Regalen, Maschinen oder anderen magnetischen Oberflächen befestigen und bietet praktischen Schutz vor Spritzern, Aerosolen und herumfliegenden Teilen
VE:
1 * 1 ST
Lieferant:
MP Biomedicals
Beschreibung:
Forskolin is the major diterpene isolated from the Indian plant Coleus forskohlii. At low doses, forskolin is a positive inotropic agent in dogs, cats, spontaneously hypertensive and normal rats and in an isolated guinea pig heart (Langendorf) preparation. At higher doses, forskolin is a hypotensive and vasodilatory agent because of its function as a smooth muscle relaxant. No major side effects are observed at effective doses.
Artikel-Nr:
(HONC15527H-25KG)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
15527H-25KG
Lokale Artikelnummer::
HONC15527H-25KG
Beschreibung:
Glycin (H-Gly-OH), erfüllt analytische Spezifikationen von BP, Ph. Eur., USP, Fluka™
VE:
1 * 25 kg
Artikel-Nr:
(BOSSBS-13536R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13536R-A680
Lokale Artikelnummer::
BOSSBS-13536R-A680
Beschreibung:
G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, PubMed:12711604, PubMed:23589301). Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. May play a role in glucose homeostasis by regulating the secretion of GLP-1, in response to short-chain fatty acids accumulating in the intestine. May also regulate the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake. Finally, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. In parallel to its role in energy homeostasis, may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, regulating the rapid production of chemokines and cytokines. May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils. In addition to SCFAs, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097).
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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