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Beschreibung:   Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
Artikel-Nr: BOSSBS-13140R-A350
VE: 1 * 100 µl
Hersteller-Artikelnummer:: BS-13140R-A350
Lokale Artikelnummer:: BOSSBS-13140R-A350
Lieferant: Bioss



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Beschreibung:   Pouring rings, made of polypropylene.
Artikel-Nr: LENZ07105400
VE: 1 * 10 ST
Hersteller-Artikelnummer:: 07105400
Lokale Artikelnummer:: LENZ07105400
Lieferant: Lenz Laborglas GmbH & CO.KG



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Beschreibung:   VWR®, Chromatographieampullen-Verschlüsse, PP, Ø: 8 mm, Typ: Schwarz, mit zentralem Loch (5,5 mm), Härte: 45° shore A, Septum: Silikon weiß/PTFE rot, Stärke: 1,3 mm
Artikel-Nr: 548-3076
VE: 1 * 100 ST
Hersteller-Artikelnummer:: 08151449
Lokale Artikelnummer:: LAPH08151449
Lieferant: LA PHA PACK



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Beschreibung:   DURAN®, borosilicate glass 3.3, clear.
Artikel-Nr: SCOT244505707
VE: 1 * 1 ST
Hersteller-Artikelnummer:: 244505707
Lokale Artikelnummer:: SCOT244505707
Lieferant: DWK Life Sciences



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Beschreibung:   4'-tert-Butylacetanilid
Artikel-Nr: MAYBRF01502.10
VE: 1 * 10 g
Hersteller-Artikelnummer:: RF01502.10
Lokale Artikelnummer:: MAYBRF01502.10
Lieferant: Thermo Scientific



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Beschreibung:   IV catheter material available in PU and FEP for low-pain and gentle insertion. Medication can be quickly administered without having to repuncture the area.
Artikel-Nr: 720-2548
VE: 1 * 50 ST
Hersteller-Artikelnummer:: 4268130B
Lokale Artikelnummer:: BRAU4268130B
Lieferant: B. Braun



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Beschreibung:   2-Chlor-6-fluorbenzaldehyd
Artikel-Nr: FLUO001426-100G
VE: 1 * 100 g
Hersteller-Artikelnummer:: 001426-100G
Lokale Artikelnummer:: FLUO001426-100G
Lieferant: FLUOROCHEM



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Beschreibung:   Anti-DFFA Mouse Monoclonal Antibody [clone: 3A11]
Artikel-Nr: USBI125785
VE: 1 * 100 µG
Hersteller-Artikelnummer:: 125785
Lokale Artikelnummer:: USBI125785
Lieferant: US Biological



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Beschreibung:   Diese Rotoren können mit Savant™ SpeedVac™-Konzentratoren mittlerer und großer Kapazität kombiniert werden.
Artikel-Nr: THSARH192-15
VE: 1 * 1 ST
Hersteller-Artikelnummer:: RH192-15
Lokale Artikelnummer:: THSARH192-15
Lieferant: THERMO SAVANT



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Beschreibung:   For the CHROMABOND® vacuum manifolds for upto 12, 16 or 24 samples the following accessories are available.
Artikel-Nr: MANA730386
VE: 1 * 4 ST
Hersteller-Artikelnummer:: 730386
Lokale Artikelnummer:: MANA730386
Lieferant: MACHEREY-NAGEL



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Beschreibung:   Flasche und Stopfen aus Borosilikatglas.
Artikel-Nr: WHEA216019
VE: 1 * 10 ST
Hersteller-Artikelnummer:: 216019
Lokale Artikelnummer:: WHEA216019
Lieferant: DWK Life Sciences



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Beschreibung:   FlaskScrubber glassware washers are designed to wash and dry narrow-neck and general purpose labware. They have a lower spindle rack that holds up to 36 pieces of primarily narrow-neck glassware such as volumetric flasks. Water and detergent are pumped through the spindles to reach the innermost areas of your glassware. Forced air drying through the spindles ensures thorough drying inside and out. Specialized inserts for pipets, BOD bottles, petri dishes, culture tubes and small utensils enhance the FlaskScrubber's versatility. The washer may be outfitted with an upper standard or spindle rack to increase capacity. FlaskScrubber is a viable option for cleaning and reuse of glassware used for trace metal, volatile organic and semi-volatile organic compounds.
Artikel-Nr: LBCP4420431
VE: 1 * 1 ST
Hersteller-Artikelnummer:: 4420431
Lokale Artikelnummer:: LBCP4420431
Lieferant: LABCONCO



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Beschreibung:   Get accurate spectroscopic readings.
Artikel-Nr: JENW99610-33
VE: 1 * 100 ST
Hersteller-Artikelnummer:: 99610-33
Lokale Artikelnummer:: JENW99610-33
Lieferant: Cole-Parmer



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Beschreibung:   PP, PE, weiß
Artikel-Nr: 216-5258
VE: 1 * 1 ST
Hersteller-Artikelnummer:: 1664
Lokale Artikelnummer:: TOUR1664
Lieferant: TOURNAIRE-EMBALLAGE



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Beschreibung:   Weißes glasiertes Porzellan.
Artikel-Nr: 511-2503
VE: 1 * 1 ST
Hersteller-Artikelnummer:: L127C/0A
Lokale Artikelnummer:: HALDL127C/0A
Lieferant: MORGAN ADVANCED MATERIALS HALD



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Beschreibung:   Diese wiederverwendbaren Kittel für Damen bestehen entweder aus 100% Baumwolle oder 65% Polyester/35% Baumwolle. Beide Stoffe sind robust, reißfest und langlebig. Die Mäntel sind mit maßgeschneidertem oder stehendem Kragen erhältlich.
Artikel-Nr: 113-1693
VE: 1 * 1 ST
Lokale Artikelnummer:: VWRI113-1693
Lieferant: VWR Collection



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